CL2013003501A1 - Composición veterinaria para combatir parásitos en animales, que comprende una lactona macrocíclica (ej. doramectina), sal de levamisol y surfactante al menos 15% p/v; uso de dicha composición - Google Patents

Composición veterinaria para combatir parásitos en animales, que comprende una lactona macrocíclica (ej. doramectina), sal de levamisol y surfactante al menos 15% p/v; uso de dicha composición

Info

Publication number
CL2013003501A1
CL2013003501A1 CL2013003501A CL2013003501A CL2013003501A1 CL 2013003501 A1 CL2013003501 A1 CL 2013003501A1 CL 2013003501 A CL2013003501 A CL 2013003501A CL 2013003501 A CL2013003501 A CL 2013003501A CL 2013003501 A1 CL2013003501 A1 CL 2013003501A1
Authority
CL
Chile
Prior art keywords
composition
doramectin
surfactant
animals
macrocyclic lactone
Prior art date
Application number
CL2013003501A
Other languages
English (en)
Inventor
Nanjan Karthigeyan
Frederick Leech Wayne
Al Alawi Fadil
Original Assignee
Bayer New Zealand Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer New Zealand Ltd filed Critical Bayer New Zealand Ltd
Publication of CL2013003501A1 publication Critical patent/CL2013003501A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing heterocyclic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Esta solicitud de invención está relacionada a una composición veterinaria para combatir parásitos en animales. La composición comprende una lactona macrocíclica (ejemplificado con doramectina), una sal de levamisol y un surfactante (agente tensoactivo) a lo menos en 15% p/v, que permite solubilizar la doramectina y mantener bioactivos ambos antiparasitarios en la composición entre valores de pH de 2 a 4. Otros componentes de la composición son un estabilizador, un antioxidante, un agente quelante y un conservante. La bioactividad de la composición está ejemplificada al inyectar la composición en vacas para eliminar huevos de los parásitos Trichostrongylus sp. y Cooperia sp., en la materia fecal de animales faenados y no faenados, y se compara con el uso del antiparasitario comercial Dectomax. La composición de la presente invención posee mayor eficacia en la eliminación de huevos de dichos parásitos en comparación con el antiparasitario comercial.
CL2013003501A 2011-06-23 2013-12-05 Composición veterinaria para combatir parásitos en animales, que comprende una lactona macrocíclica (ej. doramectina), sal de levamisol y surfactante al menos 15% p/v; uso de dicha composición CL2013003501A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NZ59371311 2011-06-23

Publications (1)

Publication Number Publication Date
CL2013003501A1 true CL2013003501A1 (es) 2014-06-27

Family

ID=47422791

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013003501A CL2013003501A1 (es) 2011-06-23 2013-12-05 Composición veterinaria para combatir parásitos en animales, que comprende una lactona macrocíclica (ej. doramectina), sal de levamisol y surfactante al menos 15% p/v; uso de dicha composición

Country Status (19)

Country Link
US (1) US9198430B2 (es)
EP (1) EP2723335A4 (es)
JP (1) JP6120834B2 (es)
KR (1) KR20140047617A (es)
CN (1) CN103717218B (es)
AU (1) AU2012273538B2 (es)
BR (1) BR112013032567B1 (es)
CA (1) CA2839491A1 (es)
CL (1) CL2013003501A1 (es)
CO (1) CO6842017A2 (es)
CR (1) CR20130642A (es)
DO (1) DOP2013000289A (es)
IL (1) IL230074A (es)
MX (1) MX355769B (es)
NI (1) NI201300139A (es)
PE (1) PE20141179A1 (es)
RU (1) RU2591082C2 (es)
UA (1) UA113179C2 (es)
WO (1) WO2012177151A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013290826B2 (en) * 2012-07-17 2018-10-18 Elanco New Zealand Injectable antibiotic formulations and their methods of use
JP6499970B2 (ja) * 2013-10-30 2019-04-10 大蔵製薬株式会社 服用し易いゼリー状医薬組成物
BR112020010297A2 (pt) * 2017-11-23 2020-11-17 Ceva Sante Animale composição para tratar infestações de parasitas

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773422A (en) * 1996-01-29 1998-06-30 Komer; Gene Avermectin formulation
AU772988B2 (en) * 1999-06-04 2004-05-13 Elanco Tiergesundheit Ag Stable biocidal compositions
NZ336139A (en) 1999-06-04 2002-07-26 Nufarm Ltd Pesticidal emulsion composition containing levamisole in the aqueous phase and an anthelmintic in the organic phase
CN1375293A (zh) 2001-03-16 2002-10-23 王玉万 含碘醚柳胺的复方注射用驱虫药
NZ520295A (en) * 2002-07-19 2005-04-29 Ashmont Holdings Ltd Anthelmintic formulations comprising levamisole and either an avermectin or milbemycin
AU2003900505A0 (en) 2003-02-05 2003-02-20 Jurox Pty Ltd Anthelmintic composition
US7645459B2 (en) * 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of bisphosphonates
BRPI0506279B1 (pt) 2005-12-16 2018-01-09 Npa - Núcleo De Pesquisas Aplicadas Ltda Composição sinergística de antihelmínticos e endectocidas
NZ552040A (en) * 2006-12-13 2009-04-30 Bomac Research Ltd Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
NZ552293A (en) 2006-12-21 2009-03-31 Bomac Research Ltd Tablet formulation comprising a macrocyclic lactone and a levamisole compound having anthelmintic activity
EP2362774A1 (en) 2008-08-18 2011-09-07 Intervet International BV Anthelmintic compositions
NZ584629A (en) * 2009-04-15 2010-12-24 Jurox Pty Ltd Anthelmintic formulation
NZ570591A (en) * 2009-08-18 2012-01-12 Intervet Int Bv Anthelmintic compositions
EP2568980B1 (en) * 2010-05-12 2015-11-11 Merial, Inc. Injectable parasiticidal formulations of levamisole and macrocyclic lactones

Also Published As

Publication number Publication date
RU2014101995A (ru) 2015-07-27
UA113179C2 (xx) 2016-12-26
MX355769B (es) 2018-04-30
US9198430B2 (en) 2015-12-01
IL230074A (en) 2016-10-31
EP2723335A1 (en) 2014-04-30
DOP2013000289A (es) 2014-03-16
CN103717218B (zh) 2017-09-12
BR112013032567A2 (pt) 2017-01-24
US20140221299A1 (en) 2014-08-07
JP2014517066A (ja) 2014-07-17
CR20130642A (es) 2014-02-19
BR112013032567B1 (pt) 2020-04-28
AU2012273538A1 (en) 2013-05-02
PE20141179A1 (es) 2014-10-11
CO6842017A2 (es) 2014-01-20
MX2013014460A (es) 2014-04-14
EP2723335A4 (en) 2015-01-07
KR20140047617A (ko) 2014-04-22
JP6120834B2 (ja) 2017-04-26
CN103717218A (zh) 2014-04-09
RU2591082C2 (ru) 2016-07-10
AU2012273538B2 (en) 2015-11-19
NI201300139A (es) 2014-02-26
CA2839491A1 (en) 2012-12-27
WO2012177151A1 (en) 2012-12-27

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