CL2013003342A1 - Microorganismo oleaginoso recombinante que produce al menos 25% de su peso seco celular como aceite y que comprende un constructo genético que codifica caleosina; metodo para aumentar la cantidad de aceite en un microorganismo oleaginoso recombinante. - Google Patents

Microorganismo oleaginoso recombinante que produce al menos 25% de su peso seco celular como aceite y que comprende un constructo genético que codifica caleosina; metodo para aumentar la cantidad de aceite en un microorganismo oleaginoso recombinante.

Info

Publication number
CL2013003342A1
CL2013003342A1 CL2013003342A CL2013003342A CL2013003342A1 CL 2013003342 A1 CL2013003342 A1 CL 2013003342A1 CL 2013003342 A CL2013003342 A CL 2013003342A CL 2013003342 A CL2013003342 A CL 2013003342A CL 2013003342 A1 CL2013003342 A1 CL 2013003342A1
Authority
CL
Chile
Prior art keywords
oil
oleaginous microorganism
recombinant oleaginous
kosine
encodes
Prior art date
Application number
CL2013003342A
Other languages
English (en)
Inventor
Seung Pyo Hong
Quinn Qun Zhu
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of CL2013003342A1 publication Critical patent/CL2013003342A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6458—Glycerides by transesterification, e.g. interesterification, ester interchange, alcoholysis or acidolysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
CL2013003342A 2011-05-26 2013-11-21 Microorganismo oleaginoso recombinante que produce al menos 25% de su peso seco celular como aceite y que comprende un constructo genético que codifica caleosina; metodo para aumentar la cantidad de aceite en un microorganismo oleaginoso recombinante. CL2013003342A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161490337P 2011-05-26 2011-05-26

Publications (1)

Publication Number Publication Date
CL2013003342A1 true CL2013003342A1 (es) 2014-08-22

Family

ID=46201843

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013003342A CL2013003342A1 (es) 2011-05-26 2013-11-21 Microorganismo oleaginoso recombinante que produce al menos 25% de su peso seco celular como aceite y que comprende un constructo genético que codifica caleosina; metodo para aumentar la cantidad de aceite en un microorganismo oleaginoso recombinante.

Country Status (8)

Country Link
US (1) US8785164B2 (es)
EP (1) EP2714724A1 (es)
JP (1) JP2014516537A (es)
CN (1) CN103562217A (es)
AU (1) AU2012258820A1 (es)
CA (1) CA2833400A1 (es)
CL (1) CL2013003342A1 (es)
WO (1) WO2012162368A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016502851A (ja) 2012-12-21 2016-02-01 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 微生物細胞中における脂質生成を改変するためのｓｏｕ２ソルビトール利用タンパク質をコードするポリヌクレオチドの下方制御
CN106574257B (zh) 2014-02-24 2021-06-04 诺沃吉公司 二酰基甘油酰基转移酶(dga1)多核苷酸，和通过异源dga1的超量表达增加酵母细胞脂质生产的方法
CN104593362B (zh) * 2015-01-08 2017-05-03 上海海洋大学 一种编码缺刻缘绿藻油体钙蛋白的dna序列及其应用
WO2016172374A1 (en) * 2015-04-21 2016-10-27 Donaldson Janet R Utilization of oleaginous microorganisms as an oral supplement for animals
CA3069630A1 (en) * 2017-07-19 2019-01-24 Alcantara Research Group Inc. Recombinant polypeptide enriched algal chloroplasts, methods for producing the same and uses thereof
CN112980709B (zh) * 2019-12-13 2022-06-03 中国科学院大连化学物理研究所 一种工程菌株及其构建方法和应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880741A (en) 1983-10-06 1989-11-14 Pfizer Inc. Process for transformation of Yarrowia lipolytica
US5071764A (en) 1983-10-06 1991-12-10 Pfizer Inc. Process for integrative transformation of yarrowia lipolytica
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5107065A (en) 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
US6753167B2 (en) 1991-02-22 2004-06-22 Sembiosys Genetics Inc. Preparation of heterologous proteins on oil bodies
US5648564A (en) 1995-12-21 1997-07-15 Kemin Industries, Inc. Process for the formation, isolation and purification of comestible xanthophyll crystals from plants
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6797303B2 (en) 2001-09-04 2004-09-28 Lycored Natural Products Industries Ltd. Carotenoid extraction process
US7238482B2 (en) 2003-05-07 2007-07-03 E. I. Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US7125672B2 (en) 2003-05-07 2006-10-24 E. I. Du Pont De Nemours And Company Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
US8313911B2 (en) 2003-05-07 2012-11-20 E I Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US7259255B2 (en) 2003-06-25 2007-08-21 E. I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast
US7267976B2 (en) 2003-07-02 2007-09-11 E.I. Du Pont De Nemours And Company Acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous yeasts
WO2005049805A2 (en) 2003-11-14 2005-06-02 E.I. Dupont De Nemours And Company Fructose-bisphosphate aldolase regulatory sequences for gene expression in oleaginous yeast
EP1766023B1 (en) 2004-06-04 2010-09-01 Fluxome Sciences A/S Metabolically engineered cells for the production of polyunsaturated fatty acids
US7465564B2 (en) 2004-08-10 2008-12-16 E.I. Du Pont De Nemours And Company Production of γ-linolenic acid in oleaginous yeast
US7550286B2 (en) 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
US7273746B2 (en) 2004-11-04 2007-09-25 E.I. Dupont De Nemours And Company Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US7256014B2 (en) 2005-07-27 2007-08-14 E. I. Du Pont De Nemours And Company Method to increase hydrophobic compound titer in a recombinant microorganism
US8846374B2 (en) 2006-12-12 2014-09-30 E I Du Pont De Nemours And Company Carotenoid production in a recombinant oleaginous yeast
EP1952695A1 (en) 2007-01-31 2008-08-06 Unilever N.V. Oil bodies and method of producing such oil bodies
ES2559312T3 (es) 2007-04-03 2016-02-11 E. I. Du Pont De Nemours And Company Multienzimas y su uso en la fabricación de ácidos grasos poliinsaturados
US7943365B2 (en) 2007-05-03 2011-05-17 E.I. Du Pont De Nemours And Company Δ-5 desaturases and their use in making polyunsaturated fatty acids
EP2195415A1 (en) 2007-10-03 2010-06-16 E. I. du Pont de Nemours and Company Optimized strains of yarrowia lipolytica for high eicosapentaenoic acid production
AU2008333824A1 (en) * 2007-12-04 2009-06-11 The Ohio State University Research Foundation Molecular approaches for the optimization of biofuel production
US8524485B2 (en) 2009-06-16 2013-09-03 E I Du Pont De Nemours And Company Long chain omega-3 and omega-6 polyunsaturated fatty acid biosynthesis by expression of acyl-CoA lysophospholipid acyltransferases
ES2574082T3 (es) * 2009-10-30 2016-06-14 Agresearch Limited Proteínas que encapsulan aceites modificados y usos de los mismos
BR112013004351A2 (pt) 2010-08-26 2016-05-31 Du Pont célula hospedeira microbiana recombinante e método para a produção de um óleo microbiano compreendendo ácido eicosapentaenócio.

Also Published As

Publication number Publication date
AU2012258820A1 (en) 2013-10-10
EP2714724A1 (en) 2014-04-09
JP2014516537A (ja) 2014-07-17
CA2833400A1 (en) 2012-11-29
US8785164B2 (en) 2014-07-22
US20120301932A1 (en) 2012-11-29
WO2012162368A1 (en) 2012-11-29
CN103562217A (zh) 2014-02-05

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