CL2011003191A1 - Uso de (6r)-2-amino-4,5,6,7- tetrahidro-6- (propilamino)benzotiazol (dexpramipexol) o sus sales para preparar un medicamento util para tratar la esclerosis lateral amiotrofica. - Google Patents

Uso de (6r)-2-amino-4,5,6,7- tetrahidro-6- (propilamino)benzotiazol (dexpramipexol) o sus sales para preparar un medicamento util para tratar la esclerosis lateral amiotrofica.

Info

Publication number
CL2011003191A1
CL2011003191A1 CL2011003191A CL2011003191A CL2011003191A1 CL 2011003191 A1 CL2011003191 A1 CL 2011003191A1 CL 2011003191 A CL2011003191 A CL 2011003191A CL 2011003191 A CL2011003191 A CL 2011003191A CL 2011003191 A1 CL2011003191 A1 CL 2011003191A1
Authority
CL
Chile
Prior art keywords
propylamino
benzothiazole
tetrahydro
salts
amino
Prior art date
Application number
CL2011003191A
Other languages
English (en)
Spanish (es)
Inventor
Valentin Bozik Michael E Gribkoff
Original Assignee
Knopp Neurosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43356795&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2011003191(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Knopp Neurosciences Inc filed Critical Knopp Neurosciences Inc
Publication of CL2011003191A1 publication Critical patent/CL2011003191A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CL2011003191A 2009-06-19 2011-12-16 Uso de (6r)-2-amino-4,5,6,7- tetrahidro-6- (propilamino)benzotiazol (dexpramipexol) o sus sales para preparar un medicamento util para tratar la esclerosis lateral amiotrofica. CL2011003191A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21865909P 2009-06-19 2009-06-19
US26794509P 2009-12-09 2009-12-09
US31711810P 2010-03-24 2010-03-24
US35643910P 2010-06-18 2010-06-18

Publications (1)

Publication Number Publication Date
CL2011003191A1 true CL2011003191A1 (es) 2012-07-20

Family

ID=43356795

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2011003191A CL2011003191A1 (es) 2009-06-19 2011-12-16 Uso de (6r)-2-amino-4,5,6,7- tetrahidro-6- (propilamino)benzotiazol (dexpramipexol) o sus sales para preparar un medicamento util para tratar la esclerosis lateral amiotrofica.

Country Status (12)

Country Link
US (2) US20110009460A1 (enExample)
EP (1) EP2442655A4 (enExample)
JP (1) JP2012530723A (enExample)
CN (1) CN102802418A (enExample)
AU (1) AU2010262970A1 (enExample)
BR (1) BRPI1010084A2 (enExample)
CA (1) CA2765876A1 (enExample)
CL (1) CL2011003191A1 (enExample)
CO (1) CO6480953A2 (enExample)
MX (1) MX2011013577A (enExample)
RU (1) RU2012101792A (enExample)
WO (1) WO2010148409A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
ES2379117T3 (es) 2006-05-16 2012-04-20 Knopp Neurosciences, Inc. Composiciones de R(+) y S(-) pramipexol y métodos de utilización de las mismas
US8524695B2 (en) 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
JP2010521496A (ja) 2007-03-14 2010-06-24 ノップ ニューロサイエンシーズ、インク． キラル精製置換ベンゾチアゾールジアミンの合成
CA2734491A1 (en) 2008-08-19 2010-02-25 Knopp Neurosciences, Inc. Compositions and methods of using (r)-pramipexole
US10272082B2 (en) 2011-07-13 2019-04-30 Cytokinetics, Inc. Combination ALS therapy
WO2013096870A1 (en) * 2011-12-22 2013-06-27 Knopp Neurosciences Inc Compositions and methods for treating amyotrophic lateral sclerosis
WO2013096816A1 (en) 2011-12-22 2013-06-27 Biogen Idec Ma Inc. Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
WO2014134569A1 (en) * 2013-02-28 2014-09-04 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
CN105764507B (zh) 2013-07-12 2019-07-19 诺普生物科学有限责任公司 治疗升高的嗜酸性粒细胞和/或嗜碱性粒细胞的水平
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
WO2015023786A1 (en) 2013-08-13 2015-02-19 Knopp Biosciences Llc Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders
EP3033081B1 (en) 2013-08-13 2021-05-12 Knopp Biosciences LLC Compositions and methods for treating chronic urticaria
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WO2016207924A1 (en) * 2015-06-25 2016-12-29 Chiarugi Alberto Dexpramipexole for the treatment of pain
WO2017103224A1 (en) * 2015-12-16 2017-06-22 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method of treatment of amyotrophic lateral sclerosis
AU2021230370A1 (en) * 2020-03-05 2022-10-20 Biohaven Therapeutics Ltd. Method of treating amyotrophic lateral sclerosis with myeloperoxidase inhibitor

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Also Published As

Publication number Publication date
CN102802418A (zh) 2012-11-28
RU2012101792A (ru) 2013-07-27
EP2442655A4 (en) 2013-04-03
US20110009460A1 (en) 2011-01-13
JP2012530723A (ja) 2012-12-06
CO6480953A2 (es) 2012-07-16
EP2442655A1 (en) 2012-04-25
WO2010148409A1 (en) 2010-12-23
CA2765876A1 (en) 2010-12-23
AU2010262970A1 (en) 2012-01-12
BRPI1010084A2 (pt) 2015-08-25
US20130245081A1 (en) 2013-09-19
MX2011013577A (es) 2012-04-10

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