CL2009001010A1 - Uso de una composicion que comprende un antagonista de progesterona para el tratamiento de una condicion dependiente de estrogenos y uso una composicion que comprende un compuesto derivado de progesterona para el tratamiento del dolor asociado con endiometrosis, hemoragia uterina disfuncional, fibroides uterinos y dismenorrea. - Google Patents

Uso de una composicion que comprende un antagonista de progesterona para el tratamiento de una condicion dependiente de estrogenos y uso una composicion que comprende un compuesto derivado de progesterona para el tratamiento del dolor asociado con endiometrosis, hemoragia uterina disfuncional, fibroides uterinos y dismenorrea.

Info

Publication number
CL2009001010A1
CL2009001010A1 CL2009001010A CL2009001010A CL2009001010A1 CL 2009001010 A1 CL2009001010 A1 CL 2009001010A1 CL 2009001010 A CL2009001010 A CL 2009001010A CL 2009001010 A CL2009001010 A CL 2009001010A CL 2009001010 A1 CL2009001010 A1 CL 2009001010A1
Authority
CL
Chile
Prior art keywords
composition
treatment
progesterone
estrogen
endiometrosis
Prior art date
Application number
CL2009001010A
Other languages
English (en)
Spanish (es)
Inventor
Joseph S Podolski
Original Assignee
Repros Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Repros Therapeutics Inc filed Critical Repros Therapeutics Inc
Publication of CL2009001010A1 publication Critical patent/CL2009001010A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36Antigestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
CL2009001010A 2008-04-28 2009-04-28 Uso de una composicion que comprende un antagonista de progesterona para el tratamiento de una condicion dependiente de estrogenos y uso una composicion que comprende un compuesto derivado de progesterona para el tratamiento del dolor asociado con endiometrosis, hemoragia uterina disfuncional, fibroides uterinos y dismenorrea. CL2009001010A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4847208P 2008-04-28 2008-04-28

Publications (1)

Publication Number Publication Date
CL2009001010A1 true CL2009001010A1 (es) 2009-06-19

Family

ID=40751037

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009001010A CL2009001010A1 (es) 2008-04-28 2009-04-28 Uso de una composicion que comprende un antagonista de progesterona para el tratamiento de una condicion dependiente de estrogenos y uso una composicion que comprende un compuesto derivado de progesterona para el tratamiento del dolor asociado con endiometrosis, hemoragia uterina disfuncional, fibroides uterinos y dismenorrea.

Country Status (24)

Country Link
US (2) US8426394B2 (https=)
EP (1) EP2293797B1 (https=)
JP (1) JP5791499B2 (https=)
KR (2) KR20110014162A (https=)
CN (2) CN102014923A (https=)
AR (1) AR071516A1 (https=)
AU (1) AU2009241355B2 (https=)
BR (1) BRPI0911563A2 (https=)
CA (1) CA2722753C (https=)
CL (1) CL2009001010A1 (https=)
DK (1) DK2293797T3 (https=)
EA (3) EA201071249A1 (https=)
ES (1) ES2561810T3 (https=)
IL (1) IL208844A0 (https=)
ME (1) ME01123B (https=)
MX (1) MX2010011272A (https=)
MY (1) MY161059A (https=)
NI (1) NI201000183A (https=)
NZ (1) NZ589533A (https=)
SG (1) SG10201408483QA (https=)
TW (1) TWI477276B (https=)
UA (1) UA102849C2 (https=)
WO (1) WO2009134718A1 (https=)
ZA (1) ZA201007529B (https=)

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UA113283C2 (xx) * 2010-12-23 2017-01-10 19-норстероїди і їх застосування для лікування прогестеронзалежних станів
EP2471537A1 (en) 2010-12-30 2012-07-04 PregLem S.A. Treatment of pain associated with dislocation of basal endometrium
US8633178B2 (en) 2011-11-23 2014-01-21 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
CA2872644A1 (en) * 2012-05-31 2013-12-05 Allergan Pharmaceuticals International Limited Formulations and methods for vaginal delivery of antiprogestins
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US9545411B2 (en) * 2012-11-02 2017-01-17 Repros Therapeutics Inc. Methods and compositions for treating progesterone-dependent conditions
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
HU230381B1 (hu) * 2014-02-17 2016-03-29 Richter Gedeon Nyrt Ipari eljárás szteroid intermedier előállítására
EP3145489A1 (en) 2014-05-22 2017-03-29 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
RU2016141135A (ru) 2014-07-29 2018-08-28 Терапьютиксмд, Инк. Трансдермальный крем
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

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Also Published As

Publication number Publication date
UA102849C2 (ru) 2013-08-27
BRPI0911563A2 (pt) 2016-07-12
AU2009241355B2 (en) 2013-11-14
SG10201408483QA (en) 2015-02-27
ES2561810T3 (es) 2016-03-01
EA201990835A3 (ru) 2019-12-30
EP2293797B1 (en) 2015-11-11
IL208844A0 (en) 2011-01-31
TW200950786A (en) 2009-12-16
US8735381B2 (en) 2014-05-27
EA032646B1 (ru) 2019-06-28
WO2009134718A8 (en) 2010-09-23
JP2011518845A (ja) 2011-06-30
MY161059A (en) 2017-04-14
EP2293797A1 (en) 2011-03-16
AR071516A1 (es) 2010-06-23
EA201990835A2 (ru) 2019-08-30
EA201401347A1 (ru) 2015-07-30
US20130289008A1 (en) 2013-10-31
NZ589533A (en) 2012-06-29
ZA201007529B (en) 2011-07-27
KR20110014162A (ko) 2011-02-10
CN105616427A (zh) 2016-06-01
AU2009241355A1 (en) 2009-11-05
KR20130059442A (ko) 2013-06-05
CA2722753C (en) 2018-07-03
DK2293797T3 (en) 2016-01-11
JP5791499B2 (ja) 2015-10-07
CA2722753A1 (en) 2009-11-05
ME01123B (me) 2013-03-20
US8426394B2 (en) 2013-04-23
US20110046098A1 (en) 2011-02-24
NI201000183A (es) 2012-06-06
WO2009134718A1 (en) 2009-11-05
MX2010011272A (es) 2010-12-21
EA201071249A1 (ru) 2011-08-30
TWI477276B (zh) 2015-03-21
CN102014923A (zh) 2011-04-13

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