CL2007000876A1 - Uso de un antagonista del factor de crecimiento endotelial vascular (vegf) en combinacion con un segundo agente que comprende un agente reductor de celula mieloide para tratar un tumor resistente en un sujeto; y metodo de diagnostico del tumor. - Google Patents
Uso de un antagonista del factor de crecimiento endotelial vascular (vegf) en combinacion con un segundo agente que comprende un agente reductor de celula mieloide para tratar un tumor resistente en un sujeto; y metodo de diagnostico del tumor.Info
- Publication number
- CL2007000876A1 CL2007000876A1 CL200700876A CL2007000876A CL2007000876A1 CL 2007000876 A1 CL2007000876 A1 CL 2007000876A1 CL 200700876 A CL200700876 A CL 200700876A CL 2007000876 A CL2007000876 A CL 2007000876A CL 2007000876 A1 CL2007000876 A1 CL 2007000876A1
- Authority
- CL
- Chile
- Prior art keywords
- tumor
- agent
- mieloid
- vegf
- antagonist
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 2
- 239000005557 antagonist Substances 0.000 title 1
- 239000003638 chemical reducing agent Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 239000003102 growth factor Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000002792 vascular Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78772006P | 2006-03-29 | 2006-03-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007000876A1 true CL2007000876A1 (es) | 2008-02-08 |
Family
ID=38564192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200700876A CL2007000876A1 (es) | 2006-03-29 | 2007-03-29 | Uso de un antagonista del factor de crecimiento endotelial vascular (vegf) en combinacion con un segundo agente que comprende un agente reductor de celula mieloide para tratar un tumor resistente en un sujeto; y metodo de diagnostico del tumor. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20070264193A1 (enExample) |
| EP (1) | EP1999151A2 (enExample) |
| JP (1) | JP2009531463A (enExample) |
| KR (1) | KR20080106946A (enExample) |
| CN (1) | CN101448856A (enExample) |
| AR (1) | AR060228A1 (enExample) |
| AU (1) | AU2007233237A1 (enExample) |
| BR (1) | BRPI0709425A2 (enExample) |
| CA (1) | CA2647430A1 (enExample) |
| CL (1) | CL2007000876A1 (enExample) |
| CR (1) | CR10325A (enExample) |
| IL (1) | IL193842A0 (enExample) |
| MA (1) | MA30348B1 (enExample) |
| MX (1) | MX2008012279A (enExample) |
| NO (1) | NO20084546L (enExample) |
| RU (1) | RU2008142775A (enExample) |
| TW (1) | TW200806322A (enExample) |
| WO (1) | WO2007115045A2 (enExample) |
| ZA (1) | ZA200807590B (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10254601A1 (de) | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| DE102004024617A1 (de) | 2004-05-18 | 2005-12-29 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| WO2006094014A2 (en) | 2005-02-28 | 2006-09-08 | The Regents Of The University Of California | Methods for diagnosis and treatment of endometrial cancer |
| US8318906B2 (en) | 2005-04-15 | 2012-11-27 | The Regents Of The University Of California | EMP2 antibodies and their therapeutic uses |
| EP1790664A1 (en) | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoclonal antibodies against claudin-18 for treatment of cancer |
| US20110118185A9 (en) * | 2007-02-21 | 2011-05-19 | Ablynx N.V. | Amino acid sequences directed against vascular endothelial growth factor and polypeptides comprising the same for the treatment of conditions and diseases characterized by excessive and/or pathological angiogenesis or neovascularization |
| CA2705486C (en) * | 2007-11-19 | 2019-04-02 | Celera Corporation | Lung cancer markers and uses thereof |
| WO2009075768A2 (en) * | 2007-12-07 | 2009-06-18 | Children's Hospital Of Orange County | Optical device and method for real-time chemosensitivity testing |
| EP2649995A3 (en) * | 2008-02-29 | 2014-05-21 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of post-radiation tumor growth |
| WO2010017083A1 (en) * | 2008-08-04 | 2010-02-11 | Wayne State University | Methods of treating cancer with cd11b antibodies |
| WO2010025414A2 (en) * | 2008-08-29 | 2010-03-04 | Genentech, Inc. | Diagnostics and treatments for vegf-independent tumors |
| US20110190380A1 (en) * | 2008-10-23 | 2011-08-04 | Elena Feinstein | Methods for delivery of sirna to bone marrow cells and uses thereof |
| US9498431B2 (en) | 2008-12-10 | 2016-11-22 | Jianjian Xu | Controlled releasing composition |
| WO2010075420A1 (en) * | 2008-12-23 | 2010-07-01 | Genentech, Inc. | Methods and compositions for diagnostic use in cancer patients |
| US7615353B1 (en) | 2009-07-06 | 2009-11-10 | Aveo Pharmaceuticals, Inc. | Tivozanib response prediction |
| AU2010278844A1 (en) * | 2009-07-31 | 2012-02-09 | Genentech, Inc. | Inhibition of tumor metastasis using Bv8- or G-CSF-antagonists |
| KR20120059553A (ko) * | 2009-08-14 | 2012-06-08 | 제넨테크, 인크. | Vegf 길항제에 대한 환자 반응을 모니터링하기 위한 생물학적 마커 |
| US7736861B1 (en) | 2009-10-19 | 2010-06-15 | Aveo Pharmaceuticals, Inc. | Tivozanib response prediction |
| JP5911805B2 (ja) | 2009-11-20 | 2016-04-27 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 上皮膜タンパク質−2(emp2)および増殖性硝子体網膜症(pvr) |
| CA2790500A1 (en) * | 2010-02-19 | 2011-08-25 | Lynn K. Gordon | Epithelial membrane protein 2 (emp2) binding reagents and their therapeutic uses in ocular diseases |
| US9375473B2 (en) | 2010-02-19 | 2016-06-28 | Cornell Research Foundation, Inc. | Method to treat autoimmune demyelinating diseases and other autoimmune or inflammatory diseases |
| KR101313184B1 (ko) * | 2010-06-24 | 2013-09-30 | 한국표준과학연구원 | 질병 지표 검출 키트 및 질병 지표 검출 방법 |
| RU2014109985A (ru) * | 2011-08-17 | 2015-09-27 | Дженентек, Инк. | Ингибирование ангиогенеза в рефрактерных опухолях |
| WO2013167153A1 (en) | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis |
| RU2502471C9 (ru) * | 2012-08-21 | 2015-04-20 | Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью населения") | Способ оценки соответствия размеров селезенки норме или отклонению от нее у детей методом ультразвуковой диагностики |
| EP2741086A1 (en) * | 2012-12-06 | 2014-06-11 | Ludwig Boltzmann Gesellschaft | Method for measuring coagulation of blood samples using viscoelastic tests (VET) |
| WO2014127785A1 (en) * | 2013-02-20 | 2014-08-28 | Ganymed Pharmaceuticals Ag | Combination therapy involving antibodies against claudin 18.2 for treatment of cancer |
| WO2014159923A1 (en) * | 2013-03-13 | 2014-10-02 | Health Research, Inc. | Enhancement of vaccines |
| RU2546105C1 (ru) * | 2014-04-29 | 2015-04-10 | Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью населения") | Способ оценки методом ультразвуковой диагностики соответствия размеров селезенки норме или отклонению от нее у детей от 3 до 15 лет |
| WO2018078158A1 (en) * | 2016-10-31 | 2018-05-03 | Hexal Ag | Antibody preparation |
| WO2020023183A1 (en) * | 2018-07-24 | 2020-01-30 | So Young Life Sciences Corporation | Use of liposomes to deliver a protein and a gene encoding the protein to a live cell |
| US20200347449A1 (en) * | 2019-05-01 | 2020-11-05 | The Broad Institute, Inc. | Methods for determining spatial and temporal gene expression dynamics during adult neurogenesis in single cells |
| CN112946291A (zh) * | 2019-12-10 | 2021-06-11 | 上海交通大学医学院附属仁济医院 | Fgf18在制备诊断和预测卵巢癌试剂中的应用及fgf18化学发光检测试剂盒 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4840793A (en) * | 1987-06-11 | 1989-06-20 | Dana-Farber Cancer Institute | Method of reducing tissue damage at an inflammatory site using a monoclonal antibody |
| US20020032313A1 (en) * | 1991-03-29 | 2002-03-14 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
| US20030206899A1 (en) * | 1991-03-29 | 2003-11-06 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
| US6582959B2 (en) * | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
| WO1994004679A1 (en) * | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| DE4422551C1 (de) * | 1994-06-28 | 1995-07-27 | Daimler Benz Ag | Durch Servomotor unterstützte Zahnstangenlenkung |
| US5871697A (en) * | 1995-10-24 | 1999-02-16 | Curagen Corporation | Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing |
| US20020032315A1 (en) * | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| WO1998045331A2 (en) * | 1997-04-07 | 1998-10-15 | Genentech, Inc. | Anti-vegf antibodies |
| US6884879B1 (en) * | 1997-04-07 | 2005-04-26 | Genentech, Inc. | Anti-VEGF antibodies |
| AU4972900A (en) * | 1999-04-08 | 2000-11-14 | Arch Development Corporation | Use of anti-vegf antibody to enhance radiation in cancer therapy |
| US6703020B1 (en) * | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
| ATE363291T1 (de) * | 2000-06-23 | 2007-06-15 | Bayer Schering Pharma Ag | Zusammensetzungen, die mit vegf/vegf und angiopoietin/tie rezeptor-funktionen interferieren |
| WO2003068155A2 (en) * | 2002-02-12 | 2003-08-21 | Vanderbilt University | Inhibition of vegf receptor signaling reverses tumor resistance to radiotherapy |
| RS20050885A (sr) * | 2003-05-30 | 2008-04-04 | Genentech | Lečenje sa anti-vegf antitelima |
| WO2005044853A2 (en) * | 2003-11-01 | 2005-05-19 | Genentech, Inc. | Anti-vegf antibodies |
| US20060009360A1 (en) * | 2004-06-25 | 2006-01-12 | Robert Pifer | New adjuvant composition |
-
2007
- 2007-03-28 MX MX2008012279A patent/MX2008012279A/es active IP Right Grant
- 2007-03-28 ZA ZA200807590A patent/ZA200807590B/xx unknown
- 2007-03-28 US US11/692,681 patent/US20070264193A1/en not_active Abandoned
- 2007-03-28 JP JP2009503253A patent/JP2009531463A/ja active Pending
- 2007-03-28 CA CA002647430A patent/CA2647430A1/en not_active Abandoned
- 2007-03-28 WO PCT/US2007/065377 patent/WO2007115045A2/en not_active Ceased
- 2007-03-28 CN CNA2007800184412A patent/CN101448856A/zh active Pending
- 2007-03-28 EP EP07759590A patent/EP1999151A2/en not_active Withdrawn
- 2007-03-28 AU AU2007233237A patent/AU2007233237A1/en not_active Abandoned
- 2007-03-28 KR KR1020087023600A patent/KR20080106946A/ko not_active Withdrawn
- 2007-03-28 BR BRPI0709425-6A patent/BRPI0709425A2/pt not_active IP Right Cessation
- 2007-03-28 RU RU2008142775/14A patent/RU2008142775A/ru not_active Application Discontinuation
- 2007-03-29 TW TW096111126A patent/TW200806322A/zh unknown
- 2007-03-29 AR ARP070101340A patent/AR060228A1/es not_active Application Discontinuation
- 2007-03-29 CL CL200700876A patent/CL2007000876A1/es unknown
-
2008
- 2008-09-02 IL IL193842A patent/IL193842A0/en unknown
- 2008-09-29 CR CR10325A patent/CR10325A/es not_active Application Discontinuation
- 2008-10-20 MA MA31315A patent/MA30348B1/fr unknown
- 2008-10-28 NO NO20084546A patent/NO20084546L/no not_active Application Discontinuation
-
2010
- 2010-04-28 US US12/769,004 patent/US20100239568A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2008012279A (es) | 2008-10-08 |
| KR20080106946A (ko) | 2008-12-09 |
| AU2007233237A1 (en) | 2007-10-11 |
| MA30348B1 (fr) | 2009-04-01 |
| JP2009531463A (ja) | 2009-09-03 |
| BRPI0709425A2 (pt) | 2011-07-12 |
| US20100239568A1 (en) | 2010-09-23 |
| ZA200807590B (en) | 2009-11-25 |
| TW200806322A (en) | 2008-02-01 |
| WO2007115045A3 (en) | 2008-04-03 |
| EP1999151A2 (en) | 2008-12-10 |
| CN101448856A (zh) | 2009-06-03 |
| WO2007115045A2 (en) | 2007-10-11 |
| US20070264193A1 (en) | 2007-11-15 |
| AR060228A1 (es) | 2008-06-04 |
| CA2647430A1 (en) | 2007-10-11 |
| RU2008142775A (ru) | 2010-05-10 |
| IL193842A0 (en) | 2011-08-01 |
| NO20084546L (no) | 2008-12-23 |
| CR10325A (es) | 2008-12-03 |
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