CH681920A5 - - Google Patents

Download PDF

Info

Publication number
CH681920A5
CH681920A5 CH1954/91A CH195491A CH681920A5 CH 681920 A5 CH681920 A5 CH 681920A5 CH 1954/91 A CH1954/91 A CH 1954/91A CH 195491 A CH195491 A CH 195491A CH 681920 A5 CH681920 A5 CH 681920A5
Authority
CH
Switzerland
Prior art keywords
grating
light
diffraction
sensitive
field
Prior art date
Application number
CH1954/91A
Other languages
German (de)
English (en)
Inventor
Kurt Dr Tiefenthaler
Original Assignee
Artificial Sensing Instr Asi A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Artificial Sensing Instr Asi A filed Critical Artificial Sensing Instr Asi A
Priority to CH1954/91A priority Critical patent/CH681920A5/de
Priority to JP4511206A priority patent/JPH06500636A/ja
Priority to EP92912252A priority patent/EP0551456A1/de
Priority to PCT/CH1992/000117 priority patent/WO1993001487A1/de
Publication of CH681920A5 publication Critical patent/CH681920A5/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0385Diffusing membrane; Semipermeable membrane

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CH1954/91A 1991-07-02 1991-07-02 CH681920A5 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CH1954/91A CH681920A5 (ja) 1991-07-02 1991-07-02
JP4511206A JPH06500636A (ja) 1991-07-02 1992-06-19 化学、生化学および生物学的な測定試料の特異物質を選択的に検出する光学的な方法
EP92912252A EP0551456A1 (de) 1991-07-02 1992-06-19 Optisches verfahren zum selektiven nachweis von spezifischen substanzen in chemischen, biochemischen und biologischen messproben
PCT/CH1992/000117 WO1993001487A1 (de) 1991-07-02 1992-06-19 Optisches verfahren zum selektiven nachweis von spezifischen substanzen in chemischen, biochemischen und biologischen messproben

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1954/91A CH681920A5 (ja) 1991-07-02 1991-07-02

Publications (1)

Publication Number Publication Date
CH681920A5 true CH681920A5 (ja) 1993-06-15

Family

ID=4222477

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1954/91A CH681920A5 (ja) 1991-07-02 1991-07-02

Country Status (4)

Country Link
EP (1) EP0551456A1 (ja)
JP (1) JPH06500636A (ja)
CH (1) CH681920A5 (ja)
WO (1) WO1993001487A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4424628A1 (de) * 1994-07-13 1996-01-18 Matthias Dipl Ing Lau Verfahren und Anordnung zur Brechzahlmessung verschiedener Medien

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0617273B1 (de) * 1993-03-26 2002-10-16 F. Hoffmann-La Roche Ag Optisches Verfahren und Vorrichtung zur Analyse von Substanzen an Sensoroberflächen
GB9314991D0 (en) * 1993-07-20 1993-09-01 Sandoz Ltd Mechanical device
US5712705A (en) * 1993-11-15 1998-01-27 Carl Zeiss Jena Gmbh Arrangement for analysis of substances at the surface of an optical sensor
DE4345225A1 (de) * 1993-11-15 1995-05-18 Hoffmann La Roche Anordnung zur Analyse von Substanzen an der Oberfläche eines optischen Sensors
GB9602542D0 (en) * 1996-02-08 1996-04-10 Fisons Plc Analytical device
JP3872817B2 (ja) 1996-03-30 2007-01-24 ノバルティス アクチエンゲゼルシャフト 集積化された光学的ルミネセンスセンサ
DE19615366B4 (de) * 1996-04-19 2006-02-09 Carl Zeiss Jena Gmbh Verfahren und Einrichtung zum Nachweis physikalischer, chemischer, biologischer oder biochemischer Reaktionen und Wechselwirkungen
CN1235673A (zh) * 1996-09-30 1999-11-17 阿温提斯研究技术两合公司 探测溶解或分散在水中的化学物质的光传感器
US8111401B2 (en) * 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
WO2004067162A2 (en) 2003-01-30 2004-08-12 Ciphergen Biosystems Inc. Apparatus for microfluidic processing and reading of biochip arrays
JP5365594B2 (ja) * 2010-09-13 2013-12-11 株式会社島津製作所 導波モード共鳴格子を用いた屈折率測定装置及び屈折率測定方法
EP2824446A1 (en) * 2013-07-12 2015-01-14 F. Hoffmann-La Roche AG Device for use in the detection of binding affinities

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007149A1 (de) * 1985-05-29 1986-12-04 Kurt Tiefenthaler Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahländerungen in messubstanzen
DE3723159A1 (de) * 1986-07-17 1988-01-21 Prosumus Ag Chemosensor sowie mit diesem durchfuehrbare verfahren
EP0455067A2 (de) * 1990-05-03 1991-11-06 F. Hoffmann-La Roche Ag Mikrooptischer Sensor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5082629A (en) * 1989-12-29 1992-01-21 The Board Of The University Of Washington Thin-film spectroscopic sensor
DE4033912C2 (de) * 1990-10-25 1995-05-24 Fraunhofer Ges Forschung Optischer Sensor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007149A1 (de) * 1985-05-29 1986-12-04 Kurt Tiefenthaler Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahländerungen in messubstanzen
DE3723159A1 (de) * 1986-07-17 1988-01-21 Prosumus Ag Chemosensor sowie mit diesem durchfuehrbare verfahren
EP0455067A2 (de) * 1990-05-03 1991-11-06 F. Hoffmann-La Roche Ag Mikrooptischer Sensor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SENSOR AND ACTUATORS. Bd. B, Nr. 1/6, 1990, LAUSANNE CH Seiten 585 - 588; W.LUKOSZ ET AL.: 'OUTPUT GRATING COUPLERS ON PLANAR WAVEGUIDES AS INTEGRATED OPTICAL SENSORS' *
SPIE, 5TH EUROPEAN CONFERENCE ON INTEGRATED OPTICS Bd. 1141, 1989, Seiten 192 - 200; W. LUKOSZ ET AL.: 'OUTPUT GRATING COUPLERS ON PLANAR WAVEGUIDES AS INTEGRATED OPTICAL SENSORS' *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4424628A1 (de) * 1994-07-13 1996-01-18 Matthias Dipl Ing Lau Verfahren und Anordnung zur Brechzahlmessung verschiedener Medien
US5812255A (en) * 1994-07-13 1998-09-22 Lau; Matthias Process and device for determining the refractive index of different mediums
DE4424628B4 (de) * 1994-07-13 2005-11-17 Lau, Matthias, Dipl.-Ing. Verfahren und Anordnung zur Brechzahlmessung verschiedener Medien

Also Published As

Publication number Publication date
WO1993001487A1 (de) 1993-01-21
EP0551456A1 (de) 1993-07-21
JPH06500636A (ja) 1994-01-20

Similar Documents

Publication Publication Date Title
EP0226604B1 (de) Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahländerungen in messubstanzen
DE3687543T2 (de) Messfuehler fuer biologische molekuele mit verwendung optischer wellenleiter.
US5455178A (en) Microoptical sensor and method
EP0617273B1 (de) Optisches Verfahren und Vorrichtung zur Analyse von Substanzen an Sensoroberflächen
DE69420375T2 (de) Matrix aus optischen biosensoren
EP1000342B1 (de) Optische detektoreinrichtung
DE69226572T2 (de) Sensorsystem mit mehreren Oberflächen für evaneszente Wellen
DE60218695T2 (de) Biosensoren und messverfahren
DE69909480T2 (de) Integriert-optischer Sensor
EP1443321A2 (de) Optischer Sensor und optisches Verfahren zur Charakterisierung einer chemischen und/oder biochemischen Substanz
DE69902023T2 (de) Nachweis einer substanz durch brechzahländerung
DE19725050C2 (de) Anordnung zur Detektion biochemischer oder chemischer Substanzen mittels Fluoreszenzlichtanregung und Verfahren zu deren Herstellung
EP2137514B1 (de) Integriert-optischer sensor
CH681920A5 (ja)
EP0938660A1 (de) Mikromechanische transmissionsmesszelle
DE3135196A1 (de) Verfahren, mittel und vorrichtung zur bestimmung biologischer komponenten
DE10002566A1 (de) Verfahren und Einrichtung zur Bestimmung des Schmelzpunktes und/oder der Bindungskonstante von Substanzen, wie z. B. DNA-Sequenzen, in einer Probe
EP0872733A1 (de) Methode zur gleichzeitigen Bestimmung von biomolekularen Wechselwirkungen mittels Plasmonenresonanz und Fluoreszenzdetektion
EP1057008A1 (de) Verfahren und vorrichtung zur lumineszenzmessung
Adrian et al. Waveguide interrogated optical immunosensor (WIOS) for detection of sulfonamide antibiotics in milk
DE4024476C1 (ja)
DE102004023402A1 (de) Verfahren zur Erhöhung des dynamischen Messbereichs von auf spezifischen Bindereaktionen basierenden, insbesondere immunologischen Testelementen
EP1079226A1 (de) Vorrichtung zur Durchführung von Immunoassays
DE3787332T2 (de) Immunassaysystem mit Verwendung von Licht-Streuung.
US5578499A (en) Homogeneous immunoassay system employing fourier transform infrared spectroscopy

Legal Events

Date Code Title Description
PL Patent ceased