CH673655A5 - - Google Patents

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Publication number
CH673655A5
CH673655A5 CH2936/87A CH293687A CH673655A5 CH 673655 A5 CH673655 A5 CH 673655A5 CH 2936/87 A CH2936/87 A CH 2936/87A CH 293687 A CH293687 A CH 293687A CH 673655 A5 CH673655 A5 CH 673655A5
Authority
CH
Switzerland
Prior art keywords
phe
boc
isobutyl
tetrafluoro
trifluoro
Prior art date
Application number
CH2936/87A
Other languages
German (de)
English (en)
Inventor
Emil Dr Pfenninger
Beat Dr Weidmann
Andre Dr Stoll
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of CH673655A5 publication Critical patent/CH673655A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
CH2936/87A 1986-08-06 1987-07-31 CH673655A5 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868619182A GB8619182D0 (en) 1986-08-06 1986-08-06 Peptides & derivatives

Publications (1)

Publication Number Publication Date
CH673655A5 true CH673655A5 (ja) 1990-03-30

Family

ID=10602311

Family Applications (1)

Application Number Title Priority Date Filing Date
CH2936/87A CH673655A5 (ja) 1986-08-06 1987-07-31

Country Status (7)

Country Link
JP (1) JPS6348295A (ja)
BE (1) BE1001618A4 (ja)
CH (1) CH673655A5 (ja)
DE (1) DE3725137A1 (ja)
FR (1) FR2602511A1 (ja)
GB (2) GB8619182D0 (ja)
IT (1) IT1211681B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071837A (en) * 1990-11-28 1991-12-10 Warner-Lambert Company Novel renin inhibiting peptides
CA2098020C (en) * 1991-01-02 2003-10-21 Daniel Schirlin Anti-viral compounds
DE69425971T2 (de) * 1993-07-08 2001-05-23 Merrell Dow Pharma Analoge von difluoro-staton
KR100308839B1 (ko) * 1993-09-09 2002-10-04 메렐 파마슈티칼스 인크. 디플루오로 스타톤 항바이러스성 유사체
US6114380A (en) * 1995-12-18 2000-09-05 Merrell Pharmaceuticals Inc. Difluoro statone analogs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0486478A3 (en) * 1984-08-06 1992-08-12 The Upjohn Company Renin-inhibiting peptides
ZA86746B (en) * 1985-02-04 1986-09-24 Merrell Dow Pharma Novel peptidase inhibitors
CH672792A5 (ja) * 1985-02-19 1989-12-29 Sandoz Ag
WO1986006379A1 (en) * 1985-04-19 1986-11-06 The Upjohn Company Dihalo-statine substituted renin inhibitors
WO1987002675A1 (en) * 1985-11-01 1987-05-07 Pfizer Inc. Difluorocyclostatine containing polypeptides
EP0297815B1 (en) * 1987-07-01 1994-07-27 Pfizer Inc. Fluorine containing renin inhibitors
JPH10183253A (ja) * 1996-12-24 1998-07-14 Nisshin Steel Co Ltd 表面性状及び加工性に優れた冷延鋼板又は溶融めっき鋼板の製造方法

Also Published As

Publication number Publication date
DE3725137A1 (de) 1988-02-11
GB2196958A (en) 1988-05-11
GB8619182D0 (en) 1986-09-17
BE1001618A4 (fr) 1989-12-19
IT1211681B (it) 1989-11-03
GB2196958B (en) 1990-07-04
IT8748235A0 (it) 1987-07-28
GB8718325D0 (en) 1987-09-09
FR2602511A1 (fr) 1988-02-12
JPS6348295A (ja) 1988-02-29

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Legal Events

Date Code Title Description
PL Patent ceased