CH652747A5 - Production d'hormone de stimulation de la thyroide humaine. - Google Patents
Production d'hormone de stimulation de la thyroide humaine. Download PDFInfo
- Publication number
- CH652747A5 CH652747A5 CH8155/81A CH815581A CH652747A5 CH 652747 A5 CH652747 A5 CH 652747A5 CH 8155/81 A CH8155/81 A CH 8155/81A CH 815581 A CH815581 A CH 815581A CH 652747 A5 CH652747 A5 CH 652747A5
- Authority
- CH
- Switzerland
- Prior art keywords
- human
- cells
- lymphoblastoids
- line
- hsth
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 34
- 229940088597 hormone Drugs 0.000 title claims description 13
- 239000005556 hormone Substances 0.000 title claims description 13
- 210000001685 thyroid gland Anatomy 0.000 title description 2
- 230000000638 stimulation Effects 0.000 title 1
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- 238000000034 method Methods 0.000 claims description 34
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- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 6
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- 102100032251 Pro-thyrotropin-releasing hormone Human genes 0.000 claims description 3
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- 239000004472 Lysine Substances 0.000 claims description 2
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
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- 238000001179 sorption measurement Methods 0.000 description 1
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- WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55187010A JPS5826317B2 (ja) | 1980-12-30 | 1980-12-30 | ヒト甲状腺刺激ホルモンの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH652747A5 true CH652747A5 (fr) | 1985-11-29 |
Family
ID=16198616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH8155/81A CH652747A5 (fr) | 1980-12-30 | 1981-12-21 | Production d'hormone de stimulation de la thyroide humaine. |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5826317B2 (OSRAM) |
| KR (1) | KR860001589B1 (OSRAM) |
| CH (1) | CH652747A5 (OSRAM) |
| FR (1) | FR2497101A1 (OSRAM) |
| GB (1) | GB2092156B (OSRAM) |
| IT (1) | IT1148019B (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS609795B2 (ja) * | 1980-12-11 | 1985-03-13 | 株式会社林原生物化学研究所 | ヒト上皮細胞成長因子の製造方法 |
| GB9015327D0 (en) * | 1990-07-12 | 1990-08-29 | Tan Kim S | Hybridomas |
| KR101789509B1 (ko) * | 2015-11-05 | 2017-10-26 | 주식회사 프로젠 | 재조합 인간 갑상선 자극 호르몬을 포함하는 조성물 및 상기 재조합 인간 갑상선 자극 호르몬의 생산 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2016015B (en) * | 1978-01-22 | 1982-05-06 | Hayashibara Co | Method of preparing interferon and preparations containing interferon |
| JPS5598118A (en) * | 1979-01-18 | 1980-07-25 | Hayashibara Takeshi | Preparation of type-2 interferon and drug containing the same |
-
1980
- 1980-12-30 JP JP55187010A patent/JPS5826317B2/ja not_active Expired
-
1981
- 1981-12-21 CH CH8155/81A patent/CH652747A5/fr not_active IP Right Cessation
- 1981-12-22 GB GB8138587A patent/GB2092156B/en not_active Expired
- 1981-12-22 IT IT49978/81A patent/IT1148019B/it active
- 1981-12-23 KR KR1019810005089A patent/KR860001589B1/ko not_active Expired
- 1981-12-28 FR FR8124269A patent/FR2497101A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GB2092156B (en) | 1984-05-10 |
| IT1148019B (it) | 1986-11-26 |
| KR860001589B1 (ko) | 1986-10-13 |
| FR2497101B1 (OSRAM) | 1984-11-09 |
| FR2497101A1 (fr) | 1982-07-02 |
| JPS57115180A (en) | 1982-07-17 |
| KR830007087A (ko) | 1983-10-14 |
| GB2092156A (en) | 1982-08-11 |
| JPS5826317B2 (ja) | 1983-06-02 |
| IT8149978A0 (it) | 1981-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |