CH620680A5 - - Google Patents

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Publication number
CH620680A5
CH620680A5 CH114876A CH114876A CH620680A5 CH 620680 A5 CH620680 A5 CH 620680A5 CH 114876 A CH114876 A CH 114876A CH 114876 A CH114876 A CH 114876A CH 620680 A5 CH620680 A5 CH 620680A5
Authority
CH
Switzerland
Prior art keywords
chloroacetyl
formula
methyl
compound
general formula
Prior art date
Application number
CH114876A
Other languages
German (de)
English (en)
Inventor
Juergen Dr Seubert
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Priority to JP8003977A priority Critical patent/JPS536600A/ja
Publication of CH620680A5 publication Critical patent/CH620680A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CH114876A 1975-02-01 1976-01-30 CH620680A5 (sv)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8003977A JPS536600A (en) 1976-01-30 1977-07-06 Banana holder

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752504250 DE2504250A1 (de) 1975-02-01 1975-02-01 Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
CH620680A5 true CH620680A5 (sv) 1980-12-15

Family

ID=5937889

Family Applications (1)

Application Number Title Priority Date Filing Date
CH114876A CH620680A5 (sv) 1975-02-01 1976-01-30

Country Status (19)

Country Link
US (1) US4362875A (sv)
JP (1) JPS6113472B2 (sv)
AT (1) AT361927B (sv)
BE (1) BE838079A (sv)
CA (1) CA1085401A (sv)
CH (1) CH620680A5 (sv)
CS (1) CS188267B2 (sv)
DE (1) DE2504250A1 (sv)
DK (1) DK37376A (sv)
ES (1) ES444804A1 (sv)
FI (1) FI62832C (sv)
FR (1) FR2299032A1 (sv)
GB (1) GB1511463A (sv)
HU (1) HU171491B (sv)
IE (1) IE42945B1 (sv)
LU (1) LU74272A1 (sv)
NL (1) NL7600985A (sv)
SE (1) SE433745B (sv)
YU (1) YU24176A (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
GB8531615D0 (en) * 1985-12-23 1986-02-05 Zambeletti Spa L Compounds
JPH055652Y2 (sv) * 1987-12-26 1993-02-15
JPH01103171U (sv) * 1987-12-26 1989-07-12
ATE97893T1 (de) * 1988-02-19 1993-12-15 Smithkline Beecham Farma 1,2,3,4-tetrahydroisoquinoline, verfharen zu ihrer herstellung und ihre verwendung als kappa- rezeptor agonisten.
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
CN100503582C (zh) * 2005-03-01 2009-06-24 江苏工业学院 吡喹酮合成工艺
EP2408771B1 (en) 2009-03-17 2016-11-16 Concert Pharmaceuticals, Inc. Pyrazinoisoquinoline compounds
CN102093346B (zh) * 2010-03-16 2012-09-05 浙江金伯士药业有限公司 一种吡喹酮的制备方法
US20140256767A1 (en) 2011-10-31 2014-09-11 The Broad Institute, Inc. Direct inhibitors of keap1-nrf2 interaction as antioxidant inflammation modulators
CN103160562B (zh) * 2013-02-28 2014-04-23 苏州同力生物医药有限公司 一种合成左旋吡喹酮的方法
US10035798B2 (en) 2015-02-12 2018-07-31 Zhejiang Hisun Pharmaceutical Co., Ltd. Preparation method for praziquantel and intermediate compounds thereof
CA2996813C (en) 2015-09-01 2023-09-26 Merck Patent Gmbh Method for the production of praziquantel and precursors thereof
WO2018063472A1 (en) 2016-09-27 2018-04-05 Reyoung Corporation Compositions for treating parasitic diseases and methods thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2361390A1 (de) * 1973-12-10 1975-06-19 Merck Patent Gmbh Isochinolinderivate und verfahren zu ihrer herstellung
US4118494A (en) * 1974-08-14 1978-10-03 Hoechst Aktiengesellschaft Substituted 3,4-dihydro-2H-isoquinolin-1-thiones

Also Published As

Publication number Publication date
ES444804A1 (es) 1977-12-01
CA1085401A (en) 1980-09-09
FI62832B (fi) 1982-11-30
ATA66576A (de) 1980-09-15
BE838079A (fr) 1976-07-30
DE2504250A1 (de) 1976-08-05
JPS6113472B2 (sv) 1986-04-14
FR2299032A1 (fr) 1976-08-27
GB1511463A (en) 1978-05-17
CS188267B2 (en) 1979-02-28
NL7600985A (nl) 1976-08-03
LU74272A1 (sv) 1977-08-03
FI760230A (sv) 1976-08-02
FR2299032B1 (sv) 1981-12-31
IE42945L (en) 1976-08-01
SE433745B (sv) 1984-06-12
DK37376A (da) 1976-08-02
JPS51101986A (sv) 1976-09-08
YU24176A (en) 1982-05-31
HU171491B (hu) 1978-01-28
SE7600954L (sv) 1976-08-02
AT361927B (de) 1981-04-10
US4362875A (en) 1982-12-07
IE42945B1 (en) 1980-11-19
FI62832C (fi) 1983-03-10

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PL Patent ceased