CH620216A5 - - Google Patents

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Publication number
CH620216A5
CH620216A5 CH1616275A CH1616275A CH620216A5 CH 620216 A5 CH620216 A5 CH 620216A5 CH 1616275 A CH1616275 A CH 1616275A CH 1616275 A CH1616275 A CH 1616275A CH 620216 A5 CH620216 A5 CH 620216A5
Authority
CH
Switzerland
Prior art keywords
cephem
formula
group
thienyl
carboxylate
Prior art date
Application number
CH1616275A
Other languages
German (de)
English (en)
Inventor
Robert Raymond Chauvette
Gary Allen Koppel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CH620216A5 publication Critical patent/CH620216A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CH1616275A 1974-12-13 1975-12-12 CH620216A5 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/532,431 US3992377A (en) 1974-12-13 1974-12-13 3-Thio-substituted cephalosporin antibiotics

Publications (1)

Publication Number Publication Date
CH620216A5 true CH620216A5 (ko) 1980-11-14

Family

ID=24121771

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1616275A CH620216A5 (ko) 1974-12-13 1975-12-12

Country Status (11)

Country Link
US (1) US3992377A (ko)
JP (1) JPS5182292A (ko)
BE (1) BE836565A (ko)
CA (1) CA1039270A (ko)
CH (1) CH620216A5 (ko)
DE (1) DE2555858A1 (ko)
FR (1) FR2293935A1 (ko)
GB (1) GB1526978A (ko)
IE (1) IE41918B1 (ko)
IL (1) IL48341A (ko)
NL (1) NL7514557A (ko)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605997A5 (ko) * 1974-08-30 1978-10-13 Ciba Geigy Ag
ZA766941B (en) * 1975-11-21 1978-06-28 Merck & Co Inc 3-(substituted thio)cephalosporins,derivatives and nuclear analogues thereof
US4150156A (en) * 1975-11-21 1979-04-17 Merck & Co., Inc. 7-(Substituted methyl)-3-(substituted thio)-cephalosporins, derivatives and pharmaceutical compositions containing them
US4197402A (en) * 1976-08-09 1980-04-08 Shionogi & Co., Ltd. Cephalosporin analogues
JPS53103493A (en) * 1977-02-18 1978-09-08 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
FR2418233A2 (fr) * 1978-02-22 1979-09-21 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkylthio ou 3-acylamino 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4739048A (en) * 1980-05-29 1988-04-19 Merck & Co., Inc. Process for the preparation of thienamycin and intermediates
US4745188A (en) * 1980-11-21 1988-05-17 Merck & Co., Inc. Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
GR76342B (ko) * 1981-02-02 1984-08-06 Fujisawa Pharmaceutical Co
JPS5984890A (ja) 1982-11-05 1984-05-16 Hisayasu Ishimaru 経口用セフアロスポリン化合物
FR2550200B1 (fr) * 1983-08-01 1988-04-08 Fujisawa Pharmaceutical Co Procede de preparation de composes de cephem a activite antimicrobienne et nouveaux produits ainsi obtenus
JPH0686459B2 (ja) * 1989-12-07 1994-11-02 明治製菓株式会社 ３―置換チオ―３―セフエム化合物の製造法
JP2857532B2 (ja) * 1992-03-12 1999-02-17 明治製菓株式会社 新規セファロスポリン誘導体
LT4193B (en) 1994-04-01 1997-07-25 Microcide Pharmaceuticals Inc Cephalosporin antibiotics
JPH09511738A (ja) * 1994-04-01 1997-11-25 マイクロサイド・ファーマシューティカルズ・インコーポレーテッド セファロスポリン抗生物質
US5688786A (en) * 1994-04-01 1997-11-18 Microcide Pharmaceuticals, Inc. β-lactam antibiotics
US5698547A (en) * 1994-04-01 1997-12-16 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US5551306A (en) * 1994-12-06 1996-09-03 Hersey Measurement Company Magnetic flowmeter
JPH10510258A (ja) * 1994-12-09 1998-10-06 藤沢薬品工業株式会社 セフェム化合物およびその医薬用途
WO1996038450A1 (en) * 1995-05-31 1996-12-05 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
MY127641A (en) * 1995-10-12 2006-12-29 Essential Therapeutics Inc Cephalosporin antibiotics
AUPN801196A0 (en) * 1996-02-12 1996-03-07 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and pharmaceutical use thereof
US6025352A (en) * 1997-09-29 2000-02-15 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US6030965A (en) * 1997-09-30 2000-02-29 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
AR035728A1 (es) * 2001-01-16 2004-07-07 Merck & Co Inc Proceso perfeccionado para la sintesis de carbapenem

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds

Also Published As

Publication number Publication date
IL48341A (en) 1980-05-30
FR2293935A1 (fr) 1976-07-09
JPS5182292A (en) 1976-07-19
DE2555858A1 (de) 1976-06-16
FR2293935B1 (ko) 1979-09-21
US3992377A (en) 1976-11-16
CA1039270A (en) 1978-09-26
IE41918L (en) 1976-06-13
BE836565A (fr) 1976-06-11
IL48341A0 (en) 1975-12-31
NL7514557A (nl) 1976-06-15
GB1526978A (en) 1978-10-04
IE41918B1 (en) 1980-04-23

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Legal Events

Date Code Title Description
PL Patent ceased