CH602582A5 - - Google Patents
Info
- Publication number
- CH602582A5 CH602582A5 CH1380076A CH1380076A CH602582A5 CH 602582 A5 CH602582 A5 CH 602582A5 CH 1380076 A CH1380076 A CH 1380076A CH 1380076 A CH1380076 A CH 1380076A CH 602582 A5 CH602582 A5 CH 602582A5
- Authority
- CH
- Switzerland
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7533899A FR2330383A1 (fr) | 1975-11-06 | 1975-11-06 | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH602582A5 true CH602582A5 (it) | 1978-07-31 |
Family
ID=9162099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1380076A CH602582A5 (it) | 1975-11-06 | 1976-11-02 |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US4252984A (it) |
| JP (1) | JPS5848543B2 (it) |
| AR (1) | AR214303A1 (it) |
| AT (1) | AT344683B (it) |
| AU (1) | AU501581B2 (it) |
| BE (1) | BE847801A (it) |
| CA (1) | CA1072981A (it) |
| CH (1) | CH602582A5 (it) |
| DE (1) | DE2649605C3 (it) |
| DK (1) | DK145119C (it) |
| ES (1) | ES452920A1 (it) |
| FI (1) | FI62829C (it) |
| FR (1) | FR2330383A1 (it) |
| GB (1) | GB1515978A (it) |
| GR (1) | GR61363B (it) |
| IE (1) | IE43645B1 (it) |
| IL (1) | IL50814A (it) |
| LU (1) | LU76117A1 (it) |
| NL (1) | NL179051C (it) |
| NO (1) | NO142034C (it) |
| NZ (1) | NZ182498A (it) |
| PT (1) | PT65780B (it) |
| SE (1) | SE433208B (it) |
| ZA (1) | ZA766338B (it) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2409980A1 (fr) * | 1977-11-24 | 1979-06-22 | Synthelabo | Ethers de phenols et leur application en therapeutique |
| IT1147311B (it) * | 1980-02-13 | 1986-11-19 | Stabil Bioterapico Farmachim | Eteri basici di 4-idrossi-benzofenoni con attivita' quali agenti betabloccanti e relativi procedimento di preparazione |
| ZW9881A1 (en) * | 1980-06-02 | 1981-12-23 | Hoffmann La Roche | Substituted phenoxyaminopropanol derivatives |
| DE3125870C2 (de) * | 1980-07-09 | 1994-09-15 | William John Louis | 3-Aminopropoxyphenyl Derivate, ihre Herstellung und sie enthaltende Arzneimittel |
| CH643527A5 (en) * | 1980-10-24 | 1984-06-15 | Ciba Geigy Ag | Process for the preparation of 1-alkylamino-3-(4-(2-lower alkoxy-ethyl)phenoxy)-2-propanols |
| US5347050A (en) * | 1980-11-06 | 1994-09-13 | Richard Berthold | 3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them |
| JPS57108047A (en) * | 1980-11-06 | 1982-07-05 | Sandoz Ag | 3-aminopropoxyphenyl derivative, manufacture and pharmaceutical composition containing same |
| FI76551C (fi) | 1980-11-06 | 1988-11-10 | Sandoz Ag | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-aminopropoxifenylderivat. |
| DE3125636A1 (de) * | 1981-06-30 | 1983-01-13 | Merck Patent Gmbh, 6100 Darmstadt | 1-(p-2-isopropoxyethoxymethyl-phenoxy)-3-isopropylamino-propan-2-ol zur senkung des augeninnendrucks und ophtalmikum, enthalten diese verbindung |
| FR2512443A1 (fr) * | 1981-09-10 | 1983-03-11 | Synthelabo | Derives de phenoxy-3 propanol-2, leur preparation et leur application en therapeutique |
| DE3151201A1 (de) * | 1981-12-23 | 1983-07-28 | Beiersdorf Ag, 2000 Hamburg | Substituierte phenoxyalkanolamine und phenoxyalkanol-cycloalkylamine, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische zubereitungen und zwischenprodukte |
| US4450172A (en) * | 1982-03-10 | 1984-05-22 | E. I. Du Pont De Nemours And Company | Antihypertensive polyhalohydroxyisopropyl phenylalka(e)noic acid esters of alkylaminohydroxypropyloxyphenylalkyl alcohols |
| FR2536390B1 (fr) * | 1982-11-22 | 1986-03-21 | Synthelabo | Isomere s du betaxolol, sa preparation et son application en therapeutique |
| CA1262729A (en) * | 1983-10-19 | 1989-11-07 | Leo Alig | Phenoxypropanolamines |
| US5166218A (en) * | 1983-10-19 | 1992-11-24 | Hoffmann-La Roche Inc. | Phenoxypropanolamines and pharmaceutical compositions thereof |
| ZA852843B (en) * | 1984-05-15 | 1985-11-27 | Warner Lambert Co | Bevantolol preparation |
| GB8412864D0 (en) * | 1984-05-19 | 1984-06-27 | Smith Kline French Lab | Chemical compounds |
| US5554367A (en) * | 1984-10-31 | 1996-09-10 | Alcon Laboratories, Inc. | Compositions for treatment of glaucoma |
| ES8609190A1 (es) * | 1985-02-07 | 1986-07-16 | Pharma Investi S A | Un procedimiento para preparar eteres fenolicos |
| US5095151A (en) * | 1985-05-21 | 1992-03-10 | American Home Products Corporation | Preparation of propranolol hydrochloride macrocrystals |
| EP0252007A3 (en) * | 1986-06-28 | 1989-07-05 | Ciba-Geigy Ag | 2-propanol derivatives as corrosion inhibitors |
| US4694022A (en) * | 1986-12-24 | 1987-09-15 | Alcon Laboratories, Inc. | Fatty acid salts of betaxolol useful in the treatment of glaucoma |
| EP0300290B1 (de) * | 1987-07-21 | 1991-12-18 | F. Hoffmann-La Roche Ag | Phenoxypropanolamine |
| FR2672594B1 (fr) * | 1991-02-08 | 1994-07-01 | Synthelabo | Derives d'ethers de phenols, leur preparation et leur application en therapeutique. |
| EP0937030B1 (en) * | 1995-10-10 | 2004-03-31 | William John Louis | 3-amino-propoxyphenyl derivatives (i) |
| CA2193149C (en) * | 1995-12-22 | 2002-04-23 | David H. Donabedian | Cationic therapuetic agents and delivery systems |
| US5942633A (en) * | 1996-06-19 | 1999-08-24 | Abbott Laboratories | Process for the selective alkylation of betaxolol intermediates |
| US5731463A (en) * | 1996-09-23 | 1998-03-24 | Abbott Laboratories | Selective alkylation of an alcohol substituted phenol compound |
| DE69942578D1 (de) | 1998-05-22 | 2010-08-26 | Univ R | Bifunktionelle moleküle sowie darauf basierende therapien. |
| US6258350B1 (en) | 1999-01-20 | 2001-07-10 | Alcon Manufacturing, Ltd. | Sustained release ophthalmic formulation |
| US7081482B2 (en) * | 1999-11-30 | 2006-07-25 | Alcon, Inc. | Use of β-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina |
| AU2001279050B2 (en) * | 2000-07-27 | 2006-10-19 | Pharmacia Corporation | Epoxy-steroidal aldosterone antagonist and beta-adrenergic antagonist combination therapy for treatment of congestive heart failure |
| EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| US7001615B1 (en) | 2001-12-07 | 2006-02-21 | Alcon, Inc. | Sustained release ophthalmic, otic and nasal suspension |
| OA12905A (en) | 2002-08-19 | 2006-10-13 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
| OA13174A (en) * | 2003-05-30 | 2006-12-13 | Ranbaxy Lab Ltd | Substituted pyrrole derivatives and their use as HMG-Co inhibitors. |
| CN1300079C (zh) * | 2004-12-03 | 2007-02-14 | 南京大学 | 合成4－[2－(环丙基甲氧基)乙基]苯酚的新工艺 |
| EP2671508B1 (en) | 2005-04-28 | 2020-09-16 | Proteus Digital Health, Inc. | Pharma-informatics system |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| CA2627599A1 (en) * | 2005-11-08 | 2007-05-18 | Ranbaxy Laboratories Limited | Process for (3r,5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxy methyl phenyl amino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid hemi calcium salt |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| WO2008020314A2 (en) * | 2006-03-14 | 2008-02-21 | Ranbaxy Laboratories Limited | Statin stabilizing dosage formulations |
| JP2009543773A (ja) * | 2006-07-14 | 2009-12-10 | ランバクシー ラボラトリーズ リミテッド | ＨＭＧ−ＣｏＡレダクターゼ阻害剤の多形体及びその使用 |
| WO2008033466A2 (en) * | 2006-09-14 | 2008-03-20 | Combinatorx (Singapore) Pre. Ltd. | Compositions and methods for treatment of viral diseases |
| EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| ES2382009T3 (es) | 2006-12-01 | 2012-06-04 | Bristol-Myers Squibb Company | Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares |
| AU2008220104B2 (en) | 2007-02-28 | 2012-09-27 | Asahi Kasei Pharma Corporation | Sulfonamide derivative |
| WO2008112287A1 (en) | 2007-03-12 | 2008-09-18 | Nektar Therapeutics | Oligomer-beta blocker conjugates |
| US8987262B2 (en) | 2007-10-19 | 2015-03-24 | Universite de Bordeaux | Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
| EP2050441A1 (en) | 2007-10-19 | 2009-04-22 | Université Victor Segalen Bordeaux 2 | Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
| JP2009040769A (ja) * | 2008-07-09 | 2009-02-26 | William John Louis | ３−アミノ−プロポキシフェニル誘導体（ｉ） |
| CA2969926C (en) | 2009-02-20 | 2018-05-15 | 2-Bbb Medicines B.V. | Glutathione-based drug delivery system |
| EP4218718A3 (en) | 2009-05-06 | 2024-04-24 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| RU2618628C1 (ru) | 2013-04-17 | 2017-05-05 | Пфайзер Инк. | Производные N-пиперидин-3-илбензамида для лечения сердечно-сосудистых заболеваний |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| EA202191892A1 (ru) | 2019-01-18 | 2022-02-24 | Астразенека Аб | Ингибиторы pcsk9 и способы их применения |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT326107B (de) * | 1935-11-15 | 1975-11-25 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von neuen racemischen oder optisch aktiven n,n'-bis- (3-subst. phenoxy-2-hydroxy-1-propyl) -alpha,omega- diaminoalkanen sowie deren säureadditionssalzen |
| GB1078852A (en) * | 1964-09-30 | 1967-08-09 | Ici Ltd | Alkanolamine derivatives |
| CA956632A (en) * | 1969-05-16 | 1974-10-22 | Yoshitomi Pharmaceutical Industries | Phenoxy-aminopropanol derivatives |
| SE372762B (it) * | 1969-05-21 | 1975-01-13 | Haessle Ab | |
| US3712890A (en) * | 1969-06-20 | 1973-01-23 | Ici Ltd | Process for making 2-aryloxymethyl morpholines |
| SE354851B (it) * | 1970-02-18 | 1973-03-26 | Haessle Ab | |
| GB1458392A (en) * | 1973-11-09 | 1976-12-15 | Ici Ltd | Optically-active 1-aryloxy-2,3-epoxypropane derivatives |
-
1975
- 1975-11-06 FR FR7533899A patent/FR2330383A1/fr active Granted
-
1976
- 1976-10-20 US US05/734,359 patent/US4252984A/en not_active Expired - Lifetime
- 1976-10-25 ZA ZA766338A patent/ZA766338B/xx unknown
- 1976-10-29 DE DE2649605A patent/DE2649605C3/de not_active Expired
- 1976-10-29 BE BE171927A patent/BE847801A/xx not_active IP Right Cessation
- 1976-11-02 NO NO763732A patent/NO142034C/no unknown
- 1976-11-02 CH CH1380076A patent/CH602582A5/xx not_active IP Right Cessation
- 1976-11-02 IL IL50814A patent/IL50814A/xx unknown
- 1976-11-02 AU AU19259/76A patent/AU501581B2/en not_active Expired
- 1976-11-02 IE IE2435/76A patent/IE43645B1/en not_active IP Right Cessation
- 1976-11-02 AR AR265315A patent/AR214303A1/es active
- 1976-11-02 NL NLAANVRAGE7612123,A patent/NL179051C/xx not_active IP Right Cessation
- 1976-11-02 DK DK495476A patent/DK145119C/da not_active IP Right Cessation
- 1976-11-02 PT PT65780A patent/PT65780B/pt unknown
- 1976-11-02 FI FI763132A patent/FI62829C/fi not_active IP Right Cessation
- 1976-11-02 NZ NZ182498A patent/NZ182498A/xx unknown
- 1976-11-02 CA CA264,650A patent/CA1072981A/en not_active Expired
- 1976-11-02 SE SE7612177A patent/SE433208B/xx active Protection Beyond IP Right Term
- 1976-11-02 GR GR52068A patent/GR61363B/el unknown
- 1976-11-02 GB GB45560/76A patent/GB1515978A/en not_active Expired
- 1976-11-02 ES ES452920A patent/ES452920A1/es not_active Expired
- 1976-11-02 AT AT812076A patent/AT344683B/de active
- 1976-11-02 JP JP51133144A patent/JPS5848543B2/ja not_active Expired
- 1976-11-03 LU LU76117A patent/LU76117A1/xx unknown
-
1979
- 1979-03-14 US US06/020,463 patent/US4311708A/en not_active Expired - Lifetime
Also Published As
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SPCF | Supplementary protection certificate filed |
Free format text: OIMC 45395, 950901 |
|
| PFA | Name/firm changed |
Owner name: SYNTHELABO,1 ET 1BIS, AVENUE DE VILLARS,PARIS 7E ( |
|
| SPCF | Supplementary protection certificate filed |
Free format text: OICM 45395/831215, 950901 |
|
| SPCG | Supplementary protection certificate granted |
Free format text: OICM 45395/831215, 950901, EXPIRES:19981215 |
|
| PL | Patent ceased |