CH599247A5 - - Google Patents

Info

Publication number
CH599247A5
CH599247A5 CH1292274A CH1292274A CH599247A5 CH 599247 A5 CH599247 A5 CH 599247A5 CH 1292274 A CH1292274 A CH 1292274A CH 1292274 A CH1292274 A CH 1292274A CH 599247 A5 CH599247 A5 CH 599247A5
Authority
CH
Switzerland
Application number
CH1292274A
Inventor
Jerome Anthony Iacobelli
Thomas Albert Narwid
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH599247A5 publication Critical patent/CH599247A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
CH1292274A 1973-11-12 1974-09-24 CH599247A5 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US415186A US3887545A (en) 1973-11-12 1973-11-12 Synthesis of 1{60 -hydroxylated cholesterol derivatives

Publications (1)

Publication Number Publication Date
CH599247A5 true CH599247A5 (cs) 1978-05-31

Family

ID=23644712

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1292274A CH599247A5 (cs) 1973-11-12 1974-09-24

Country Status (9)

Country Link
US (1) US3887545A (cs)
JP (1) JPS5438098B2 (cs)
AT (1) AT342793B (cs)
BE (1) BE821983A (cs)
CH (1) CH599247A5 (cs)
DE (1) DE2453648C3 (cs)
FR (1) FR2250764B1 (cs)
GB (1) GB1443680A (cs)
NL (1) NL7414675A (cs)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4264512A (en) * 1975-09-29 1981-04-28 The Regents Of The University Of California 3-Deoxy-1α-hydroxy- and 3-deoxy-1α,25-dihydroxycholecalciferol and processes for the preparation thereof
JPS603045B2 (ja) * 1976-04-19 1985-01-25 中外製薬株式会社 1α―ヒドロキシビタミンD類軟カプセルの製造方法
US4098801A (en) * 1977-01-26 1978-07-04 Hoffmann-La Roche Inc. Synthesis of 1α-hydroxylated derivatives of cholesterol
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
LU80545A1 (de) * 1978-11-17 1980-06-05 Hoffmann La Roche Verfahren zur herstellung von 1a,3s-dihydroxy->5-steroiden
US4217279A (en) * 1978-12-18 1980-08-12 Kaiser Emil T Synthesis of steroids
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
ATE238339T1 (de) 1996-12-20 2003-05-15 Novo Nordisk As Verbindungen zur regulierung der meiose
JP2002543216A (ja) * 1999-04-30 2002-12-17 アーチ ディベロップメント コーポレイション ステロイド誘導体
EP1385868A4 (en) * 2001-02-08 2004-12-08 Univ Chicago STEROID DERIVATIVE
US20070197484A1 (en) * 2001-05-03 2007-08-23 Ching Song Method of treating disorder related to high cholesterol concentration
US7078396B2 (en) * 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
EP1494533A2 (en) * 2002-04-12 2005-01-12 The University of Chicago Farnesoid x-activated receptor agonists
AU2003268260B2 (en) * 2002-08-29 2008-04-10 The Regents Of The University Of California Agents and methods for enhancing bone formation
WO2005020928A2 (en) * 2003-08-29 2005-03-10 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
US20070032464A1 (en) * 2004-10-08 2007-02-08 Shutsung Liao Methods of treating cancers
DE112006001754A5 (de) * 2005-04-23 2008-04-10 Ixetic Bad Homburg Gmbh Axialkolbenmaschine
JP2009512422A (ja) * 2005-09-02 2009-03-26 ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 骨形成及び抗脂肪細胞形成オキシステロール類
WO2007098281A2 (en) * 2006-02-27 2007-08-30 Regents Of The University Of California Oxysterol compounds and the hedgehog pathway
WO2008011071A2 (en) * 2006-07-19 2008-01-24 The Regents Of The University Of California Interactions of hedgehog and liver x receptor signaling pathways
US8022052B2 (en) 2006-12-19 2011-09-20 The Regents Of The University Of California Inhibition of PPAR gamma expression by specific osteogenic oxysterols
US20100112030A1 (en) * 2007-03-16 2010-05-06 The Regents Of The University Of California Role of hedgehog signaling in atherosclerosis and cardiovascular disease
US9526737B2 (en) * 2007-12-03 2016-12-27 The Regents Of The University Of California Oxysterols for activation of hedgehog signaling, osteoinduction, antiadipogenesis, and Wnt signaling
CA2769203A1 (en) * 2009-07-29 2011-02-03 University Of Chicago Liver x receptor agonists
US9717742B2 (en) 2012-05-07 2017-08-01 The Regents Of The University Of California Oxysterol analogue OXY133 induces osteogenesis and hedgehog signaling and inhibits adipogenesis
CA2911205A1 (en) 2013-05-02 2014-11-06 The Regents Of The University Of California Bone-selective osteogenic oxysterol-bone targeting agents
CN114315947B (zh) * 2021-11-17 2023-10-03 王涛 一种由22-甾醇作为原料合成胆固醇和25-羟基胆固醇的新方法
CN116514892B (zh) * 2022-01-28 2025-07-18 珂阑(上海)医药科技有限公司 甾类化合物、其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080937A (en) * 1960-11-07 1963-03-12 Garbell Res Foundation Combined acoustic wall and exhaust gas deflector in operation of jet engines
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol

Also Published As

Publication number Publication date
NL7414675A (nl) 1975-05-14
FR2250764A1 (cs) 1975-06-06
GB1443680A (en) 1976-07-21
AT342793B (de) 1978-04-25
ATA899274A (de) 1977-08-15
JPS5438098B2 (cs) 1979-11-19
FR2250764B1 (cs) 1979-08-03
DE2453648A1 (de) 1975-05-15
JPS5077360A (cs) 1975-06-24
US3887545A (en) 1975-06-03
DE2453648B2 (de) 1980-06-26
DE2453648C3 (de) 1981-08-06
BE821983A (fr) 1975-05-09

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Legal Events

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