CH599215A5 - - Google Patents

Info

Publication number
CH599215A5
CH599215A5 CH958777A CH958777A CH599215A5 CH 599215 A5 CH599215 A5 CH 599215A5 CH 958777 A CH958777 A CH 958777A CH 958777 A CH958777 A CH 958777A CH 599215 A5 CH599215 A5 CH 599215A5
Authority
CH
Switzerland
Application number
CH958777A
Inventor
Adolf Dr Langbein
Herbert Dr Merz
Gerhard Dr Walther
Klaus Dr Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of CH599215A5 publication Critical patent/CH599215A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/09Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
    • C07D489/10Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
    • C07D489/12Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH958777A 1972-06-19 1973-06-14 CH599215A5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2229770A DE2229770A1 (de) 1972-06-19 1972-06-19 N-(heteroarylmethyl)-7alpha-acyl6,14-endoaethenotetrahydro-nororipavine und -thebaine, deren hydrierungsprodukte und saeureadditionssalze sowie verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
CH599215A5 true CH599215A5 (es) 1978-05-12

Family

ID=5848095

Family Applications (6)

Application Number Title Priority Date Filing Date
CH958677A CH597234A5 (es) 1972-06-19 1973-06-14
CH958777A CH599215A5 (es) 1972-06-19 1973-06-14
CH958377A CH599214A5 (es) 1972-06-19 1973-06-14
CH958477A CH597233A5 (es) 1972-06-19 1973-06-14
CH958577A CH596212A5 (es) 1972-06-19 1973-06-14
CH864473A CH598260A5 (es) 1972-06-19 1973-06-14

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH958677A CH597234A5 (es) 1972-06-19 1973-06-14

Family Applications After (4)

Application Number Title Priority Date Filing Date
CH958377A CH599214A5 (es) 1972-06-19 1973-06-14
CH958477A CH597233A5 (es) 1972-06-19 1973-06-14
CH958577A CH596212A5 (es) 1972-06-19 1973-06-14
CH864473A CH598260A5 (es) 1972-06-19 1973-06-14

Country Status (14)

Country Link
US (1) US3931187A (es)
JP (1) JPS5732073B2 (es)
AT (6) AT328095B (es)
BE (1) BE801083A (es)
CH (6) CH597234A5 (es)
DE (1) DE2229770A1 (es)
DK (1) DK140408C (es)
ES (5) ES416038A1 (es)
FI (1) FI56180C (es)
FR (1) FR2189054B1 (es)
GB (1) GB1430958A (es)
NL (1) NL7308482A (es)
NO (1) NO137998C (es)
SE (1) SE409035B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62298530A (ja) * 1986-06-16 1987-12-25 Otsuka Pharmaceut Co Ltd 坐薬用医薬組成物
NZ333101A (en) * 1997-03-27 2000-05-26 Toray Industries Morphinane derivatives useful for the treatment of pain
WO2011154826A1 (en) 2010-06-11 2011-12-15 Rhodes Technologies Process for n-dealkylation of tertiary amines
AU2011263417B2 (en) 2010-06-11 2014-03-27 Rhodes Technologies Transition metal-catalyzed processes for the preparation of N-allyl compounds and use thereof
US9315514B2 (en) 2012-08-27 2016-04-19 Rhodes Technologies 1,3-dioxanomorphides and 1,3-dioxanocodides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3474101A (en) * 1960-09-05 1969-10-21 Reckitt & Sons Ltd Thebaine and oripavine derivatives
GB1223445A (en) * 1968-07-18 1971-02-24 Reckitt & Colmann Prod Ltd Improvements in or relating to derivatives of morphine, their salts, and processes for their preparation
US3560505A (en) * 1969-05-15 1971-02-02 American Cyanamid Co Substituted 7-(1-alkoxy - 1 - alken-1-yl)-7,8-dihydro-6-methoxy-6,14-endo- (etheno or ethano) codides and morphides
US3562279A (en) * 1969-05-15 1971-02-09 American Cyanamid Co Substituted 7,8-dihydro - 6 - methoxy-6,14-endo(etheno or ethano)morphide - 7-ketones and n-cycloalkylmethyl - 7,8-dihydro - 6 - methoxy-6,14-endo(etheno or ethano) norcodide-7-ketones
DE2107989A1 (de) * 1971-02-19 1972-09-07 Boehringer Sohn Ingelheim N-(Furyl-methy])-morphinane, deren Säureadditionssalze sowie Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
AU5704773A (en) 1974-12-19
ES424309A1 (es) 1976-06-16
ATA265974A (de) 1975-05-15
CH599214A5 (es) 1978-05-12
FI56180B (fi) 1979-08-31
US3931187A (en) 1976-01-06
SE409035B (sv) 1979-07-23
AT325217B (de) 1975-10-10
AT328625B (de) 1976-03-25
CH596212A5 (es) 1978-03-15
BE801083A (fr) 1973-12-18
CH597234A5 (es) 1978-03-31
AT328095B (de) 1976-03-10
AT328626B (de) 1976-03-25
FI56180C (fi) 1979-12-10
AT328096B (de) 1976-03-10
FR2189054A1 (es) 1974-01-25
ES416038A1 (es) 1976-06-16
CH597233A5 (es) 1978-03-31
JPS5732073B2 (es) 1982-07-08
ATA265674A (de) 1975-05-15
ES424308A1 (es) 1976-06-16
JPS4961188A (es) 1974-06-13
NO137998C (no) 1978-06-07
AT328097B (de) 1976-03-10
ES424307A1 (es) 1976-07-01
GB1430958A (en) 1976-04-07
NL7308482A (es) 1973-12-21
ES424310A1 (es) 1976-06-16
DK140408C (da) 1980-01-21
ATA265874A (de) 1975-05-15
ATA265774A (de) 1975-06-15
DE2229770A1 (de) 1974-01-10
FR2189054B1 (es) 1976-12-31
NO137998B (no) 1978-02-27
CH598260A5 (es) 1978-04-28
DK140408B (da) 1979-08-20

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Legal Events

Date Code Title Description
PL Patent ceased