US4780409A
(en)
*
|
1985-05-02 |
1988-10-25 |
Genetic Systems Corporation |
Thermally induced phase separation immunoassay
|
US5206344A
(en)
*
|
1985-06-26 |
1993-04-27 |
Cetus Oncology Corporation |
Interleukin-2 muteins and polymer conjugation thereof
|
US4766106A
(en)
*
|
1985-06-26 |
1988-08-23 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polymer conjugation
|
JPH0433452Y2
(es)
*
|
1986-02-12 |
1992-08-11 |
|
|
US4959305A
(en)
*
|
1986-06-18 |
1990-09-25 |
Miles Inc. |
Reversible immobilization of assay reagents in a multizone test device
|
EP0261836B1
(en)
*
|
1986-09-17 |
1993-07-14 |
Beecham Group Plc |
Immobilised enzyme preparation and its use
|
US4894226A
(en)
*
|
1986-11-14 |
1990-01-16 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polyproline conjugation
|
US4847325A
(en)
*
|
1988-01-20 |
1989-07-11 |
Cetus Corporation |
Conjugation of polymer to colony stimulating factor-1
|
US5306500A
(en)
*
|
1988-11-21 |
1994-04-26 |
Collagen Corporation |
Method of augmenting tissue with collagen-polymer conjugates
|
US5162430A
(en)
*
|
1988-11-21 |
1992-11-10 |
Collagen Corporation |
Collagen-polymer conjugates
|
US5565519A
(en)
*
|
1988-11-21 |
1996-10-15 |
Collagen Corporation |
Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
|
US5510418A
(en)
*
|
1988-11-21 |
1996-04-23 |
Collagen Corporation |
Glycosaminoglycan-synthetic polymer conjugates
|
US5166322A
(en)
*
|
1989-04-21 |
1992-11-24 |
Genetics Institute |
Cysteine added variants of interleukin-3 and chemical modifications thereof
|
AU4104093A
(en)
*
|
1992-04-20 |
1993-11-18 |
Rufeld, Inc. |
Method and compositions for treatment of pyonecrotic processes
|
US5545553A
(en)
*
|
1994-09-26 |
1996-08-13 |
The Rockefeller University |
Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
|
US6833408B2
(en)
*
|
1995-12-18 |
2004-12-21 |
Cohesion Technologies, Inc. |
Methods for tissue repair using adhesive materials
|
US6458889B1
(en)
|
1995-12-18 |
2002-10-01 |
Cohesion Technologies, Inc. |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
|
EP1704878B1
(en)
*
|
1995-12-18 |
2013-04-10 |
AngioDevice International GmbH |
Crosslinked polymer compositions and methods for their use
|
US7883693B2
(en)
*
|
1995-12-18 |
2011-02-08 |
Angiodevice International Gmbh |
Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
|
EP0874893A2
(en)
*
|
1995-12-29 |
1998-11-04 |
The Procter & Gamble Company |
Detergent compositions comprising immobilized enzymes
|
US6008037A
(en)
*
|
1996-11-14 |
1999-12-28 |
Polymer Technology Corporation |
Use of water soluble enzyme-polymer conjugates for cleaning contact lenses
|
CN1329082C
(zh)
*
|
1998-10-16 |
2007-08-01 |
拜奥根Idec马萨诸塞公司 |
干扰素-β-1a的聚合物缀合物及其使用
|
DK1578771T3
(da)
*
|
2001-10-10 |
2013-06-10 |
Novo Nordisk As |
Remodellering og glycokonjugering af peptider
|
EP2322229B1
(en)
|
2001-10-10 |
2016-12-21 |
Novo Nordisk A/S |
Remodeling and glycoconjugation of Factor IX
|
US7179617B2
(en)
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
US7696163B2
(en)
|
2001-10-10 |
2010-04-13 |
Novo Nordisk A/S |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7265085B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycoconjugation methods and proteins/peptides produced by the methods
|
US7399613B2
(en)
*
|
2001-10-10 |
2008-07-15 |
Neose Technologies, Inc. |
Sialic acid nucleotide sugars
|
US7265084B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7297511B2
(en)
*
|
2001-10-10 |
2007-11-20 |
Neose Technologies, Inc. |
Interferon alpha: remodeling and glycoconjugation of interferon alpha
|
US7125843B2
(en)
*
|
2001-10-19 |
2006-10-24 |
Neose Technologies, Inc. |
Glycoconjugates including more than one peptide
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
US7157277B2
(en)
*
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US7226903B2
(en)
*
|
2001-10-10 |
2007-06-05 |
Neose Technologies, Inc. |
Interferon beta: remodeling and glycoconjugation of interferon beta
|
US7795210B2
(en)
*
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
US7214660B2
(en)
*
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US8008252B2
(en)
*
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
US7439043B2
(en)
*
|
2001-10-10 |
2008-10-21 |
Neose Technologies, Inc. |
Galactosyl nucleotide sugars
|
US7473680B2
(en)
*
|
2001-11-28 |
2009-01-06 |
Neose Technologies, Inc. |
Remodeling and glycoconjugation of peptides
|
MXPA04012496A
(es)
*
|
2002-06-21 |
2005-09-12 |
Novo Nordisk Healthcare Ag |
Glicoformos del factor vii pegilados.
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
CA2511486A1
(en)
*
|
2002-12-30 |
2004-07-22 |
Angiotech International Ag |
Tissue reactive compounds and compositions and uses thereof
|
JP2006516548A
(ja)
*
|
2002-12-30 |
2006-07-06 |
アンジオテック インターナショナル アクツィエン ゲゼルシャフト |
迅速ゲル化ポリマー組成物からの薬物送達法
|
NZ542094A
(en)
*
|
2003-03-14 |
2008-12-24 |
Neose Technologies Inc |
Branched polymer conjugates comprising a peptide and water-soluble polymer chains
|
WO2007022512A2
(en)
*
|
2005-08-19 |
2007-02-22 |
Neose Technologies, Inc. |
Glycopegylated factor vii and factor viia
|
SG155777A1
(en)
|
2003-04-09 |
2009-10-29 |
Neose Technologies Inc |
Glycopegylation methods and proteins/peptides produced by the methods
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
US7691603B2
(en)
*
|
2003-04-09 |
2010-04-06 |
Novo Nordisk A/S |
Intracellular formation of peptide conjugates
|
WO2006127896A2
(en)
*
|
2005-05-25 |
2006-11-30 |
Neose Technologies, Inc. |
Glycopegylated factor ix
|
EP1624847B1
(en)
|
2003-05-09 |
2012-01-04 |
BioGeneriX AG |
Compositions and methods for the preparation of human growth hormone glycosylation mutants
|
WO2005012484A2
(en)
|
2003-07-25 |
2005-02-10 |
Neose Technologies, Inc. |
Antibody-toxin conjugates
|
US7842661B2
(en)
*
|
2003-11-24 |
2010-11-30 |
Novo Nordisk A/S |
Glycopegylated erythropoietin formulations
|
US8633157B2
(en)
*
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
US7405198B2
(en)
*
|
2003-11-24 |
2008-07-29 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US20080305992A1
(en)
*
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US20080318850A1
(en)
*
|
2003-12-03 |
2008-12-25 |
Neose Technologies, Inc. |
Glycopegylated Factor Ix
|
US20060040856A1
(en)
*
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
US7956032B2
(en)
*
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
ES2422187T3
(es)
*
|
2003-12-03 |
2013-09-09 |
Biogenerix Ag |
Factor estimulante de colonias de granulocitos glicopegilados
|
EP1765853B1
(en)
*
|
2004-01-08 |
2015-10-28 |
ratiopharm GmbH |
O-linked glycosylation of G-CSF peptides
|
JP4124361B2
(ja)
*
|
2004-02-16 |
2008-07-23 |
農工大ティー・エル・オー株式会社 |
化学物質の分離方法
|
NZ550964A
(en)
|
2004-04-28 |
2011-05-27 |
Angiodevice Internat Gmbh |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
|
RU2006138181A
(ru)
*
|
2004-05-04 |
2008-06-10 |
Ново Нордиск Хелс Кеа Аг (Ch) |
О-связанные гликоформы полипептидов и способ их изготовления
|
WO2006010143A2
(en)
|
2004-07-13 |
2006-01-26 |
Neose Technologies, Inc. |
Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
|
WO2006031811A2
(en)
*
|
2004-09-10 |
2006-03-23 |
Neose Technologies, Inc. |
Glycopegylated interferon alpha
|
EP1796602A4
(en)
|
2004-09-17 |
2016-10-19 |
Angiotech Pharm Inc |
MULTIFUNCTIONAL COMPOUNDS FOR PRODUCING NETWORKED BIOMATERIALS AND MANUFACTURING AND USE METHOD THEREFOR
|
US20080108557A1
(en)
*
|
2004-09-29 |
2008-05-08 |
Novo Nordisk Healthcare A/G |
Modified Proteins
|
EP3061461A1
(en)
*
|
2004-10-29 |
2016-08-31 |
ratiopharm GmbH |
Remodeling and glycopegylation of fibroblast growth factor (fgf)
|
EP1838332A1
(en)
*
|
2005-01-06 |
2007-10-03 |
Neose Technologies, Inc. |
Glycoconjugation using saccharyl fragments
|
ES2449195T3
(es)
|
2005-01-10 |
2014-03-18 |
Ratiopharm Gmbh |
Factor estimulante de colonias de granulocitos glicopegilado
|
WO2006105426A2
(en)
*
|
2005-03-30 |
2006-10-05 |
Neose Technologies, Inc. |
Manufacturing process for the production of peptides grown in insect cell lines
|
WO2006121569A2
(en)
*
|
2005-04-08 |
2006-11-16 |
Neose Technologies, Inc. |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
US20070105755A1
(en)
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
WO2007056191A2
(en)
*
|
2005-11-03 |
2007-05-18 |
Neose Technologies, Inc. |
Nucleotide sugar purification using membranes
|
WO2009140373A2
(en)
|
2008-05-13 |
2009-11-19 |
Advanced Liquid Logic, Inc. |
Droplet actuator devices, systems, and methods
|
US20080274958A1
(en)
*
|
2006-07-21 |
2008-11-06 |
Neose Technologies, Inc. |
Glycosylation of peptides via o-linked glycosylation sequences
|
US8969532B2
(en)
*
|
2006-10-03 |
2015-03-03 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
|
MX2009003470A
(es)
*
|
2006-10-04 |
2009-04-14 |
Novo Nordisk As |
Azucares y glicopeptidos pegilados enlazados a glicerol.
|
WO2008073620A2
(en)
*
|
2006-11-02 |
2008-06-19 |
Neose Technologies, Inc. |
Manufacturing process for the production of polypeptides expressed in insect cell-lines
|
NZ580030A
(en)
|
2007-04-03 |
2012-06-29 |
Biogenerix Ag |
Methods of treatment using glycopegylated g-csf
|
US20090053167A1
(en)
*
|
2007-05-14 |
2009-02-26 |
Neose Technologies, Inc. |
C-, S- and N-glycosylation of peptides
|
US20110177029A1
(en)
*
|
2007-06-04 |
2011-07-21 |
Novo Nordisk A/S |
O-linked glycosylation using n-acetylglucosaminyl transferases
|
WO2008154639A2
(en)
*
|
2007-06-12 |
2008-12-18 |
Neose Technologies, Inc. |
Improved process for the production of nucleotide sugars
|
CN104689333B
(zh)
|
2007-08-27 |
2018-05-29 |
拉蒂奥法姆有限责任公司 |
G-csf 缀合物的液体制剂
|
US8207112B2
(en)
*
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
SG185263A1
(en)
*
|
2007-09-28 |
2012-11-29 |
Portola Pharm Inc |
Antidotes for factor xa inhibitors and methods of using the same
|
KR20190085187A
(ko)
|
2008-01-22 |
2019-07-17 |
아라임 파마슈티칼즈, 인크. |
조직 손상 관련 질환 및 장애를 예방 및 치료하기 위한 조직 보호 펩티드 및 펩티드 유사체
|
KR101582841B1
(ko)
|
2008-02-27 |
2016-01-11 |
노보 노르디스크 에이/에스 |
콘쥬게이트된 인자 viii 분자
|
SG11201406492YA
(en)
|
2012-04-16 |
2014-11-27 |
Cantab Biopharmaceuticals Patents Ltd |
Optimised subcutaneous therapeutic agents
|
JP2019523633A
(ja)
|
2016-04-29 |
2019-08-29 |
アライム ファーマシューティカルズ,インコーポレーテッド |
組織の損傷に関連した疾患及び障害を予防及び治療する組織保護ペプチド
|