CH546250A - Triazolobenzodiazepine derivs - with anticonvulsant, cns depressant and muscle-relaxant activity - Google Patents

Triazolobenzodiazepine derivs - with anticonvulsant, cns depressant and muscle-relaxant activity

Info

Publication number
CH546250A
CH546250A CH546250DA CH546250A CH 546250 A CH546250 A CH 546250A CH 546250D A CH546250D A CH 546250DA CH 546250 A CH546250 A CH 546250A
Authority
CH
Switzerland
Prior art keywords
muscle
triazolobenzodiazepine
derivs
anticonvulsant
oxides
Prior art date
Application number
Other languages
German (de)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of CH546250A publication Critical patent/CH546250A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Title cpds. of formula (I): (where R1 is H or 1-3C alkyl; R2 is 1-4C alkyl or R2--R2 is a satd. divalent 2-5C aliphatic hydrocarbon residue, and rings A and B can be substd. by F, Cl, Br, CF3, NO2 or 1-6C alkyl or alkoxy) and their 5-oxides and acid addn. salts, can be used as tranquillisers, sedatives, muscle relaxants and anti-epileptics; the 5-oxides are also of use as inters. for further pharmacologically active cpds. Cpds. (I) are e.g. prepd. by (a) reacting a 2-X-3-R1-5-phenyl-3H-1,4-benzodiazepine (where X is SH, lower alkoxy or alkylthio opt. activated by a substituent, or opt. mono- or disubstd. amino) with (R2O)2CHCONHNH2. The 5-oxides are obtd. by oxidn.
CH546250D 1971-04-08 1971-04-08 Triazolobenzodiazepine derivs - with anticonvulsant, cns depressant and muscle-relaxant activity CH546250A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1212873 1971-04-08

Publications (1)

Publication Number Publication Date
CH546250A true CH546250A (en) 1974-02-28

Family

ID=4380132

Family Applications (1)

Application Number Title Priority Date Filing Date
CH546250D CH546250A (en) 1971-04-08 1971-04-08 Triazolobenzodiazepine derivs - with anticonvulsant, cns depressant and muscle-relaxant activity

Country Status (1)

Country Link
CH (1) CH546250A (en)

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Legal Events

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PL Patent ceased