CH522407A - Procédé pour la préparation de solutions pour usages parentéral, oral et topique de la doxycycline - Google Patents

Procédé pour la préparation de solutions pour usages parentéral, oral et topique de la doxycycline

Info

Publication number
CH522407A
CH522407A CH933769A CH933769A CH522407A CH 522407 A CH522407 A CH 522407A CH 933769 A CH933769 A CH 933769A CH 933769 A CH933769 A CH 933769A CH 522407 A CH522407 A CH 522407A
Authority
CH
Switzerland
Prior art keywords
doxycycline
parenteral
oral
solutions
preparation
Prior art date
Application number
CH933769A
Other languages
English (en)
French (fr)
Inventor
Ernst Beutel Rolf
Christel Lohlbach Kathe
Wilhelm Raaf Helmut
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5699525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH522407(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of CH522407A publication Critical patent/CH522407A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CH933769A 1968-06-28 1969-06-18 Procédé pour la préparation de solutions pour usages parentéral, oral et topique de la doxycycline CH522407A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1767891A DE1767891C3 (de) 1968-06-28 1968-06-28 Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat

Publications (1)

Publication Number Publication Date
CH522407A true CH522407A (fr) 1972-06-30

Family

ID=5699525

Family Applications (1)

Application Number Title Priority Date Filing Date
CH933769A CH522407A (fr) 1968-06-28 1969-06-18 Procédé pour la préparation de solutions pour usages parentéral, oral et topique de la doxycycline

Country Status (18)

Country Link
US (1) US3674859A (OSRAM)
AT (1) AT291441B (OSRAM)
BE (1) BE734723A (OSRAM)
BR (1) BR6909929D0 (OSRAM)
CH (1) CH522407A (OSRAM)
DE (1) DE1767891C3 (OSRAM)
DK (1) DK127168B (OSRAM)
ES (1) ES368496A1 (OSRAM)
FI (1) FI44395B (OSRAM)
FR (1) FR2011764B1 (OSRAM)
GB (1) GB1228629A (OSRAM)
IE (1) IE33167B1 (OSRAM)
IL (1) IL32350A (OSRAM)
MX (1) MX3351E (OSRAM)
MY (1) MY7300015A (OSRAM)
NL (1) NL6908919A (OSRAM)
NO (1) NO130624C (OSRAM)
SE (1) SE373036B (OSRAM)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
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US3957980A (en) * 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
GB1350196A (en) * 1972-10-26 1974-04-18 Pfizer Doxycyline parenteral composition
US3928592A (en) * 1974-02-22 1975-12-23 Lilly Co Eli Antibiotic pharmaceutical compositions
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
EP1666453A1 (en) 1999-09-14 2006-06-07 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
CA2397863A1 (en) * 2000-01-24 2001-07-26 Trustees Of Tufts College Tetracycline compounds for treatment of cryptosporidium parvum related disorders
ES2288945T3 (es) * 2000-03-31 2008-02-01 Trustees Of Tufts College Compuestos de tetraciclina 7 y 9-carbamato, urea, tiourea, tiocarbamato y heteroaril-amino sustituidos.
DE60102815D1 (de) * 2000-05-15 2004-05-19 Paratek Pharm Innc 7-substituierte kondensierte ring-tetrazyclin- verbindungen
US20040224927A1 (en) * 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
AU2001268475A1 (en) * 2000-06-16 2002-01-02 Trustees Of Tufts College 7-phenyl-substituted tetracycline compounds
US7094806B2 (en) 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
DE60144375D1 (de) 2000-07-07 2011-05-19 Trustees Of Tufts College Medford 7-, 8- und 9-substitutierte tetracyclinverbindungen
SI1301467T1 (sl) 2000-07-07 2007-02-28 Tufts College 9-substituirane minociklinske spojine
EP1301465A2 (en) 2000-07-07 2003-04-16 Trustees Of Tufts College 13-substituted methacycline compounds
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
EA006170B1 (ru) * 2000-07-07 2005-10-27 Трастис Оф Тафтс Коллидж Замещенные соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния субъекта
US6683068B2 (en) * 2001-03-13 2004-01-27 Paratek Pharmaceuticals, Inc. 7, 9-substituted tetracycline compounds
CA2440757A1 (en) 2001-03-14 2002-09-19 Michael Draper Substituted tetracycline compounds as synergistic antifungal agents
US6841546B2 (en) 2001-03-14 2005-01-11 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as antifungal agents
DE60235083D1 (de) 2001-04-24 2010-03-04 Paratek Pharm Innc Substituierte tetracyclin-verbindungen zur behandlung von malaria
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
JP2005514410A (ja) 2002-01-08 2005-05-19 パラテック ファーマシューティカルズ インコーポレイテッド ４−デジメチルアミノテトラサイクリン化合物
JP2005516032A (ja) 2002-01-23 2005-06-02 デンツプライ インターナショナル インコーポレーテッド 洗浄液とその使用法
JP2005526754A (ja) 2002-03-08 2005-09-08 パラテック ファーマシューティカルズ インコーポレイテッド アミノメチル置換されたテトラサイクリン化合物
JP2005520846A (ja) 2002-03-21 2005-07-14 パラテック ファーマシューティカルズ インコーポレイテッド 置換されたテトラサイクリン化合物。
EP1534300A4 (en) 2002-07-12 2008-04-23 Paratek Pharm Innc TETRACYCLINE COMPOUNDS SUBSTITUTED IN 3, 10, AND 12A
AU2003287218C1 (en) 2002-10-24 2010-07-15 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
CA2531732C (en) 2003-07-09 2012-04-10 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
EP2319828A3 (en) 2003-07-09 2011-07-06 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
AU2004261143B2 (en) * 2003-07-25 2009-11-05 Allergan Pharmaceuticals International Limited A doxycycline metal complex in a solid dosage form
EP2332904A3 (en) 2004-01-15 2012-04-11 Paratek Pharmaceuticals, Inc. Derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP2287148A3 (en) 2004-10-25 2011-10-26 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
EP1805134B1 (en) * 2004-10-25 2012-06-20 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
NZ556582A (en) * 2005-01-21 2010-12-24 Warner Chilcott Co Llc A tetracycline metal complex in a solid dosage form
JP2008530023A (ja) * 2005-02-04 2008-08-07 パラテック ファーマシューティカルズ インコーポレイテッド テトラサイクリン化合物の１１ａ，１２−誘導体
WO2007014154A2 (en) * 2005-07-21 2007-02-01 Paratek Pharmaceuticals, Inc. 10-substituted tetracyclines and methods of use thereof
EP1991236A2 (en) 2006-01-24 2008-11-19 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
JP4205731B2 (ja) * 2006-04-05 2009-01-07 株式会社日本触媒 ポリビニルピロリドン粉体組成物およびその製造方法
WO2007120913A2 (en) * 2006-04-17 2007-10-25 Teva Pharmaceutical Industries Ltd. Isolation of tetracycline derivatives
CN101479235B (zh) * 2006-04-24 2013-09-18 特瓦制药工业有限公司 替加环素晶形及其制备方法
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
AU2007249695A1 (en) * 2006-05-15 2007-11-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
WO2008045507A2 (en) 2006-10-11 2008-04-17 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of bacillus anthracis infections
PT2109602E (pt) 2006-12-21 2014-05-23 Paratek Pharm Innc Derivados de tetraciclina para o tratamento de infecções bacterianas, virais e parasitárias
SI2120963T1 (sl) 2006-12-21 2019-02-28 Paratek Pharmaceuticals, Inc. Substituirane spojine tetraciklina za zdravljenje vnetnih kožnih motenj
JP5121470B2 (ja) * 2007-01-26 2013-01-16 株式会社日本触媒 ポリビニルピロリドン粉体組成物
US7935687B2 (en) * 2007-04-12 2011-05-03 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
CA2688662A1 (en) 2007-04-27 2008-11-06 Paratek Pharmaceuticals, Inc. Methods for synthesizing and purifying aminoalkyl tetracycline compounds
ATE555079T1 (de) 2007-07-06 2012-05-15 Paratek Pharm Innc Verfahren zur synthese von 9-substituiertem minocyclin
CN102015602A (zh) 2008-03-05 2011-04-13 帕拉特克药品公司 米诺环素化合物及其使用方法
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
US20100022483A1 (en) * 2008-04-14 2010-01-28 Paratek Pharmaceuticals, Inc. Substituted Tetracycline Compounds
TW202021946A (zh) 2008-05-19 2020-06-16 美商派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
AP2011005631A0 (en) * 2008-09-19 2011-04-30 Paratek Pharmaceuticals Ind Tetracycline compounds for the treatment of rheumatoid arthritis and related methods of treatment.
EP3061460A1 (en) 2009-04-10 2016-08-31 Tufts Medical Center, Inc. Par-1 activation by metalloproteinase-1 (mmp-1)
RU2647972C2 (ru) 2010-05-12 2018-03-21 Ремпекс Фармацеутикалс, Инк. Тетрациклиновая композиция
CN101862293B (zh) * 2010-06-22 2012-02-29 华南农业大学 盐酸多西环素的油混悬液及其制备方法和应用
WO2012155146A1 (en) 2011-05-12 2012-11-15 Paratek Pharmaceuticals, Inc. Crystalline salts of (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide and methods of using the same
PT108978B (pt) 2015-11-24 2020-03-09 Hovione Farm S A Sais de tetraciclinas
CN110087655A (zh) 2016-11-01 2019-08-02 帕拉特克药品公司 9-氨基甲基米诺环素化合物及其在治疗社区获得性细菌性肺炎(cabp)中的用途
WO2019016609A1 (en) 2017-07-21 2019-01-24 Allergan Pharmaceuticals International Limited TREATMENT OF NON-INFLAMMATORY LESIONS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (OSRAM) * 1960-05-23 1966-05-25

Also Published As

Publication number Publication date
BE734723A (OSRAM) 1969-12-18
US3674859A (en) 1972-07-04
DE1767891B2 (de) 1980-02-21
NO130624B (OSRAM) 1974-10-07
BR6909929D0 (pt) 1973-02-08
FR2011764A1 (OSRAM) 1970-03-06
MX3351E (es) 1980-10-08
AT291441B (de) 1971-07-12
SE373036B (OSRAM) 1975-01-27
IE33167L (en) 1969-12-28
IL32350A0 (en) 1969-08-27
IL32350A (en) 1972-05-30
DK127168B (da) 1973-10-01
GB1228629A (OSRAM) 1971-04-15
NO130624C (OSRAM) 1975-01-15
MY7300015A (en) 1973-12-31
FR2011764B1 (OSRAM) 1973-07-13
DE1767891A1 (de) 1971-07-08
IE33167B1 (en) 1974-04-03
NL6908919A (OSRAM) 1969-12-30
DE1767891C3 (de) 1980-10-30
ES368496A1 (es) 1971-05-01
FI44395B (OSRAM) 1971-08-02

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