CH475258A - Verfahren zur Herstellung einer Cytosinverbindung - Google Patents
Verfahren zur Herstellung einer CytosinverbindungInfo
- Publication number
- CH475258A CH475258A CH1376966A CH1376966A CH475258A CH 475258 A CH475258 A CH 475258A CH 1376966 A CH1376966 A CH 1376966A CH 1376966 A CH1376966 A CH 1376966A CH 475258 A CH475258 A CH 475258A
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- cytosine compound
- cytosine
- compound
- Prior art date
Links
- 229940104302 cytosine Drugs 0.000 title 1
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Natural products NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 title 1
- -1 cytosine compound Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US502586A US3309359A (en) | 1965-10-22 | 1965-10-22 | N-mono-acyl-5-fluorocytosine derivatives and process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH475258A true CH475258A (de) | 1969-07-15 |
Family
ID=23998481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1376966A CH475258A (de) | 1965-10-22 | 1966-09-23 | Verfahren zur Herstellung einer Cytosinverbindung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3309359A (de) |
| BE (1) | BE688539A (de) |
| BR (1) | BR6683864D0 (de) |
| CH (1) | CH475258A (de) |
| DE (1) | DE1695160A1 (de) |
| DK (1) | DK115474B (de) |
| FR (1) | FR5908M (de) |
| GB (1) | GB1110357A (de) |
| IL (1) | IL26726A (de) |
| NL (1) | NL6614240A (de) |
| SE (1) | SE330176B (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3894000A (en) * | 1971-01-27 | 1975-07-08 | Upjohn Co | Ara-cytidine derivatives and process of preparation |
| US3975367A (en) * | 1971-06-08 | 1976-08-17 | The Upjohn Company | Arabinofuranosyl N4 -aminoacyl cytosine containing compounds |
| US4022963A (en) * | 1972-06-08 | 1977-05-10 | Deutsch Daniel Harold | Acetylation process for nucleoside compounds |
| US3991045A (en) * | 1973-05-30 | 1976-11-09 | Asahi Kasei Kogyo Kabushiki Kaisha | N4 -acylarabinonucleosides |
| JPS5159880A (en) * | 1974-11-22 | 1976-05-25 | Asahi Chemical Ind | N44 ashirunukureoshidojikarubonsanesuteruno seiho |
| JPS5924999B2 (ja) * | 1978-06-10 | 1984-06-13 | 富山化学工業株式会社 | 新規な5−フルオロ−2′−デオキシ−β−ウリジン誘導体の製造法 |
| JPS5535057A (en) * | 1978-09-05 | 1980-03-11 | Funai Corp | 2'-deoxy-5-fluorouridine derivative, its preparation, and antitumor agent comprising it |
| JPS59167600A (ja) * | 1983-03-14 | 1984-09-21 | Microbial Chem Res Found | 2′−デオキシオキザノシンおよびその製造法 |
| CN100560073C (zh) | 2001-12-14 | 2009-11-18 | 法玛塞特公司 | 用于治疗病毒感染的n4-酰基胞嘧啶核苷 |
| EP2562175A1 (de) | 2008-01-22 | 2013-02-27 | Dow AgroSciences LLC | 5-fluor-pyrimidinderivate als fungizide |
| EP2647287A1 (de) | 2008-08-01 | 2013-10-09 | Dow AgroSciences LLC | Verwendung von 5-Fluorcytosin und dessen Derivate als Fungizide |
| UA106889C2 (uk) * | 2009-08-07 | 2014-10-27 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Похідні n1-ацил-5-фторпіримідинону |
| UA112284C2 (uk) * | 2009-08-07 | 2016-08-25 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Похідні 5-фторпіримідинону |
| JP5784603B2 (ja) | 2009-08-07 | 2015-09-24 | ダウ アグロサイエンシィズ エルエルシー | N1−スルホニル−5−フルオロピリミジノン誘導体 |
| UA107671C2 (en) * | 2009-08-07 | 2015-02-10 | Dow Agrosciences Llc | N1-substityted-5-fluoro-2-oxopyrimidinone-1(2h)-carboxamide derivatives |
| CA2786250A1 (en) * | 2010-01-07 | 2011-07-14 | Dow Agrosciences Llc | Thiazolo[5,4-d] pyrimidines and their use as agrochemicals |
| ES2646725T3 (es) | 2011-08-17 | 2017-12-15 | Adama Makhteshim Ltd. | Derivados 1-sustituidos de 5-fluoro-3,6-dihidro-6-imino-2(1H)-pirimidinona como agentes fungicidas para uso en protección de plantas |
| KR20150103096A (ko) | 2012-12-28 | 2015-09-09 | 다우 아그로사이언시즈 엘엘씨 | N-(치환된)-5-플루오로-4-이미노-3-메틸-2-옥소-3,4-디히드로피리미딘-1(2h)-카르복실레이트 유도체 |
| MX2015008444A (es) | 2012-12-28 | 2015-09-23 | Dow Agrosciences Llc | Derivados de n-(sustituido)-5-flouro-4-imino-3-metil-2-oxo-3,4-dih idropirimidin-1 (2h)-carboximida. |
| EP2945635A4 (de) | 2012-12-28 | 2016-05-25 | Dow Agrosciences Llc | 1-(substituierte-benzoyl) -5-fluor-4-imino-3-methyl-3,4-dihydropyrimidin-2 (1h)-on-derivate |
| CA2894553C (en) | 2012-12-31 | 2021-03-02 | Dow Agrosciences Llc | 3-alkyl-5-fluoro-4-substituted-imino-3,4-dihydropyrimidin-2(1h)-one derivatives as fungicides |
| EA030056B1 (ru) | 2013-12-31 | 2018-06-29 | Адама Мактешим Лтд. | Синергетические фунгицидные смеси и синергетические фунгицидные композиции для борьбы с грибами |
| SG11201605377VA (en) | 2013-12-31 | 2016-08-30 | Adama Makhteshim Ltd | 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation |
| IL309708B1 (en) | 2017-07-17 | 2025-10-01 | Adama Makhteshim Ltd | Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-4,3-dihydropyrimidin-2-one |
| CN109651467A (zh) * | 2019-01-15 | 2019-04-19 | 齐鲁天和惠世制药有限公司 | 一种卡培他滨杂质及其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2949451A (en) * | 1959-04-21 | 1960-08-16 | Hoffmann La Roche | Preparation of thymidine and deoxyfluorouridine, and intermediates therefor |
| NL299755A (de) * | 1959-06-03 | |||
| US3208997A (en) * | 1962-11-15 | 1965-09-28 | Sankyo Co | Process for preparing purine and pyrimidine nucleosides |
-
1965
- 1965-10-22 US US502586A patent/US3309359A/en not_active Expired - Lifetime
-
1966
- 1966-09-23 CH CH1376966A patent/CH475258A/de not_active IP Right Cessation
- 1966-09-26 DE DE19661695160 patent/DE1695160A1/de active Pending
- 1966-10-10 NL NL6614240A patent/NL6614240A/xx unknown
- 1966-10-20 FR FR80695A patent/FR5908M/fr not_active Expired
- 1966-10-20 SE SE14339/66A patent/SE330176B/xx unknown
- 1966-10-20 IL IL26726A patent/IL26726A/xx unknown
- 1966-10-20 BE BE688539D patent/BE688539A/xx unknown
- 1966-10-21 GB GB47304/66A patent/GB1110357A/en not_active Expired
- 1966-10-21 DK DK547566AA patent/DK115474B/da unknown
- 1966-10-21 BR BR183864/66A patent/BR6683864D0/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL26726A (en) | 1970-06-17 |
| BE688539A (de) | 1967-04-20 |
| BR6683864D0 (pt) | 1973-12-26 |
| GB1110357A (en) | 1968-04-18 |
| SE330176B (de) | 1970-11-09 |
| US3309359A (en) | 1967-03-14 |
| FR5908M (de) | 1968-03-25 |
| DK115474B (da) | 1969-10-13 |
| DE1695160A1 (de) | 1970-12-17 |
| NL6614240A (de) | 1967-04-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |