CH388332A - Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten - Google Patents

Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Info

Publication number
CH388332A
CH388332A CH462764A CH462764A CH388332A CH 388332 A CH388332 A CH 388332A CH 462764 A CH462764 A CH 462764A CH 462764 A CH462764 A CH 462764A CH 388332 A CH388332 A CH 388332A
Authority
CH
Switzerland
Prior art keywords
preparation
basic substituted
diphenylalkane
derivatives
diphenylalkane derivatives
Prior art date
Application number
CH462764A
Other languages
German (de)
English (en)
Inventor
Ehrhart Gustav Dr Prof
Ott Heinrich
Ernst Dr Lindner
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CH388332A publication Critical patent/CH388332A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH462764A 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten CH388332A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF25702A DE1111642B (de) 1958-05-07 1958-05-07 Verfahren zur Herstellung von basisch substituierten Diphenylmethan-Derivaten mit Herz- und Kreislaufwirksamkeit

Publications (1)

Publication Number Publication Date
CH388332A true CH388332A (de) 1965-02-28

Family

ID=7091732

Family Applications (8)

Application Number Title Priority Date Filing Date
CH708765A CH397710A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH7291559A CH385878A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463264A CH388329A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463064A CH396931A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462864A CH388333A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462964A CH388334A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462764A CH388332A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463164A CH388328A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Family Applications Before (6)

Application Number Title Priority Date Filing Date
CH708765A CH397710A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH7291559A CH385878A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463264A CH388329A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463064A CH396931A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462864A CH388333A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462964A CH388334A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH463164A CH388328A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Country Status (10)

Country Link
US (1) US3152173A (US20060009399A1-20060112-C00060.png)
BE (1) BE578515A (US20060009399A1-20060112-C00060.png)
CH (8) CH397710A (US20060009399A1-20060112-C00060.png)
CY (1) CY277A (US20060009399A1-20060112-C00060.png)
DE (1) DE1111642B (US20060009399A1-20060112-C00060.png)
FR (1) FR553M (US20060009399A1-20060112-C00060.png)
GB (1) GB916644A (US20060009399A1-20060112-C00060.png)
MY (1) MY6400049A (US20060009399A1-20060112-C00060.png)
NL (2) NL238796A (US20060009399A1-20060112-C00060.png)
OA (1) OA01363A (US20060009399A1-20060112-C00060.png)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3262977A (en) * 1962-03-10 1966-07-26 Chinoin Gyogyszer Es Vegyeszet N-aralkyl-1, 1-diphenyl-propylamine derivatives
NL296693A (US20060009399A1-20060112-C00060.png) * 1962-08-16
FR95908E (fr) * 1963-11-09 1972-01-31 Degussa Procédé de préparation de nouvelles aminocétones et des alcools secondaires correspondants.
US3457354A (en) * 1965-09-21 1969-07-22 Merck & Co Inc Treatment of hypertension with 2-hydroxy (or amino) - 4,5 - dihydroxyphenethylamine derivatives
US3895057A (en) * 1967-10-13 1975-07-15 Dainippon Pharmaceutical Co Aminoalkanols and their pharmaceutically acceptable acid-addition salts, and production thereof
US4329367A (en) * 1974-08-05 1982-05-11 Ciba-Geigy Corporation 1-(Aralkoxyphenyl)-2-(bis-arylalkylamino)-alkanes
DE2902172C2 (de) * 1979-01-20 1984-05-10 UOP Inc., 60016 Des Plaines, Ill. Verfahren zur Herstellung eines N,N'-Dialkylphenylendiamins
WO1983003755A1 (en) * 1982-04-23 1983-11-10 Caola Kozmetikai És Háztartäsvegyipari Vállalat Novel cosmetic compositions containing prenylamine and a process for their preparation
NZ215753A (en) * 1985-04-16 1989-10-27 Hoffmann La Roche Phenethanolamine derivatives and pharmaceutical compositions
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
CN1658903A (zh) * 2001-01-26 2005-08-24 先灵公司 用于治疗血管性疾病的固醇吸收抑制剂与血液调节剂的组合
ATE369851T1 (de) * 2001-01-26 2007-09-15 Schering Corp Kombinationen von gallensäuresequestriermitteln und hemmern der sterolabsorption zur behandlung von kardiovaskulären indikationen
BR0206644A (pt) * 2001-01-26 2004-02-25 Schering Corp Combinações de inibidor(es) de absorção de esteróis com agente(s) cardiovascular(es) para o tratamento de condições vasculares
US20020183305A1 (en) * 2001-01-26 2002-12-05 Schering Corporation Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
KR100596257B1 (ko) * 2001-01-26 2006-07-03 쉐링 코포레이션 스테롤 흡수 억제제를 포함하는 조성물, 및 페록시솜 증식인자-활성화 수용체 활성화제와 스테롤 흡수 억제제를 포함하는 조성물 및 조합물
KR100820983B1 (ko) * 2001-01-26 2008-04-10 쉐링 코포레이션 치환된 아제티딘온 화합물을 포함하는 약제학적 조성물
AR038956A1 (es) * 2001-05-25 2005-02-02 Schering Corp Uso de un compuesto que regula la produccion o niveles de peptidos beta amiloides para la manufactura de un medicamento para tratar la enfermedad de alzheimer y/o para regular dichos niveles de peptidos amiloides beta en un sujeto
CA2460340C (en) * 2001-09-21 2011-02-15 Schering Corporation Methods and therapeutic combinations for the treatment of xanthoma using sterol absorption inhibitors
MXPA04002572A (es) * 2001-09-21 2004-05-31 Schering Corp Metodos para el tratamiento o prevencion de inflamacion vascular usando inhibidores de absorcion de esterol.
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
AU2003250483A1 (en) 2002-08-19 2004-03-11 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
AU2003291719A1 (en) * 2002-11-06 2004-06-03 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
DE602004016123D1 (de) 2003-03-07 2008-10-09 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
CA2517573C (en) * 2003-03-07 2011-12-06 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
ATE418551T1 (de) 2003-03-07 2009-01-15 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
US20050096307A1 (en) * 2003-11-05 2005-05-05 Schering Corporation Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
EP1796653A2 (en) * 2004-07-26 2007-06-20 Actelion Pharmaceuticals Ltd. Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
EP2351569B1 (en) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
ATE551059T1 (de) * 2005-10-26 2012-04-15 Asahi Kasei Pharma Corp Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EA020466B1 (ru) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012037665A1 (en) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体
CN113388007A (zh) 2013-06-05 2021-09-14 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
JOP20210193A1 (ar) 2019-01-18 2023-01-30 Astrazeneca Ab مثبطات pcsk9 وطرق استخدامها

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2601323A (en) * 1949-02-02 1952-06-24 Upjohn Co Process for preparing 4, 4-diphenyl-6-dimethylamino-heptanone-3
US2681934A (en) * 1950-01-06 1954-06-22 Commercial Solvents Corp Substituted diphenylalkylamines
US2797242A (en) * 1953-08-11 1957-06-25 Parke Davis & Co Substituted alpha-benzylphenethylamines and methods for producing the same
US2738347A (en) * 1954-12-13 1956-03-13 Olin Mathieson Penicillin salt of benzhydryl-phenethylamine
US2872374A (en) * 1955-02-02 1959-02-03 Nat Drug Co Muscle-relaxing tranquilizer compositions
US2894033A (en) * 1955-11-15 1959-07-07 Nl Combinatie Chem Ind Antispasmodic 1, 1-diphenyl-3-dialkylaminopropane, and its tertiary and quaternary salts
US2854379A (en) * 1956-06-06 1958-09-30 Miles Lab Tranquilizing composition comprising 2-ethyl-cis-crotonylurea
DE1058063B (de) * 1957-02-08 1959-05-27 Hoechst Ag Verfahren zur Herstellung von analgetisch wirksamen substituierten Phenylaethylaminen

Also Published As

Publication number Publication date
OA01363A (fr) 1969-07-04
CH396931A (de) 1965-08-15
CH388328A (de) 1965-02-28
NL108640C (US20060009399A1-20060112-C00060.png)
US3152173A (en) 1964-10-06
CH397710A (de) 1965-08-31
FR553M (US20060009399A1-20060112-C00060.png) 1961-05-29
CH385878A (de) 1964-12-31
CH388334A (de) 1965-02-28
DE1111642B (de) 1961-07-27
GB916644A (en) 1963-01-23
MY6400049A (en) 1964-12-31
CH388333A (de) 1965-02-28
BE578515A (US20060009399A1-20060112-C00060.png)
NL238796A (US20060009399A1-20060112-C00060.png)
CH388329A (de) 1965-02-28
CY277A (en) 1964-02-12

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