CH221823A - Process for the preparation of a new benzimidazole derivative. - Google Patents

Process for the preparation of a new benzimidazole derivative.

Info

Publication number
CH221823A
CH221823A CH221823DA CH221823A CH 221823 A CH221823 A CH 221823A CH 221823D A CH221823D A CH 221823DA CH 221823 A CH221823 A CH 221823A
Authority
CH
Switzerland
Prior art keywords
benzimidazole derivative
new benzimidazole
preparation
acid
new
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH221823A publication Critical patent/CH221823A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Detergent Compositions (AREA)

Description

  

  Verfahren     zur        Herstellunb    eines neuen     Benzimidazolderivates.       Es wurde gefunden, dass man zu einem  neuen     Benzimidazolderivat    gelangt, wenn  man     ,u    -     heptad@ecylbenzimidazolsulfon@sa..ures     Natrium in wässeriger Lösung mit     Chloramei-          sensäuremethylester    umsetzt.  



  Die Umsetzung wird zweckmässig in der  Wärme, z. B. bei     50-6,0',    vorteilhaft in  Gegenwart     eines    säurebindenden Mittels, wie       Natriumbicarbonat,    ausgeführt.  



  Das so erhältliche neue     Benzimidazol-          derivat    ist ein weisses Pulver, das von Was  ser zu einer klaren, gegen Ameisensäure be  ständigen Lösung aufgenommen wird. Es  kann als     Textilhilfsmittel,    z. B. als Wasch  mittel, Anwendung finden.  



  <I>Beispiel:</I>  46 Teile     ,u-heptadecylbenzimidazolsulfon-          saures    Natrium werden mit 8,5 Teilen Na  triumbicarbonat in 900 Teilen Wasser bei  54-57   gelöst und unter Rühren innerhalb    40 Minuten mit 9,5 Teilen Chlorameisen  säuremethylester versetzt. Darauf wird wäh  rend einer halben .Stunde bei der gleichen  Temperatur     weiter    gerührt. Die so erhaltene  Lösung reagiert ganz schwach alkalisch.  Nach dem Eindampfen im Vakuum bei 100    erhält man ein weisses Pulver, das sich in  Wasser klar löst. Die Säurebeständigkeit ist  gegenüber dem Ausgangsmaterial sehr stark  verbessert.

   Eine     wässerige    Lösung des     Um-          setzungsproJuktes        wird    beim Ansäuern mit  Ameisensäure viskos, bleibt jedoch     vollstän-          dig    klar. Das Ausgangsmaterial wird aus  einer neutralen     wässerigen    Lösung beim An  säuern     mit    Ameisensäure     quantitativ    ge  fällt.



  Process for the production of a new benzimidazole derivative. It has been found that a new benzimidazole derivative is obtained if u - heptad @ ecylbenzimidazolesulfon @ acidic sodium is reacted in an aqueous solution with methyl chloroformate.



  The implementation is expediently in the heat, for. B. at 50-6.0 ', advantageously carried out in the presence of an acid-binding agent such as sodium bicarbonate.



  The new benzimidazole derivative available in this way is a white powder that is absorbed by water to form a clear solution that is resistant to formic acid. It can be used as a textile auxiliary, e.g. B. as detergent, find application.



  <I> Example: </I> 46 parts of u-heptadecylbenzimidazolesulphonic acid sodium are dissolved with 8.5 parts of sodium bicarbonate in 900 parts of water at 54-57 and, while stirring, 9.5 parts of methyl chloroformate are added over the course of 40 minutes. It is then stirred for half an hour at the same temperature. The solution obtained in this way has a very weak alkaline reaction. After evaporation in vacuo at 100, a white powder is obtained which dissolves clearly in water. The acid resistance is very much improved compared to the starting material.

   An aqueous solution of the reaction product becomes viscous on acidification with formic acid, but remains completely clear. The starting material is quantitatively precipitated from a neutral aqueous solution when acidified with formic acid.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung eines neuen Benzimidazolderivates, dadurch gekennzeich net, dass man ,u-heptadecylbenzimidazolsul- fonsaures Natrium in wässeriger Lösung mit Chlorameisensäuremethylester umsetzt. Das so erhältliche neue Benzimidazol- derivat ist ein weisses Pulver, das von Was ser zu einer klaren, gegen Ameisensäure be ständigen Lösung aufgenommen wird. Es kann als Textilhilfsmittel, z. B. als Wasch- mittel, Anwendung finden. PATENT CLAIM: Process for the production of a new benzimidazole derivative, characterized in that u-heptadecylbenzimidazole sulphonic acid is reacted in an aqueous solution with methyl chloroformate. The new benzimidazole derivative available in this way is a white powder that is absorbed by water to form a clear solution that is resistant to formic acid. It can be used as a textile auxiliary, e.g. B. as a detergent, use. U'-\-TERA:#-SPRUCFI Verfahren nach Patentanspruch, dadurch 0ehennzeiehnet, dass man in Gegenwart eines säurebindenden Mittels arbeitet. U '- \ - TERA: # - SPRUCFI Process according to patent claim, characterized in that one works in the presence of an acid-binding agent.
CH221823D 1940-10-24 1940-10-24 Process for the preparation of a new benzimidazole derivative. CH221823A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH218363T 1940-10-24
CH221823T 1940-10-24

Publications (1)

Publication Number Publication Date
CH221823A true CH221823A (en) 1942-06-15

Family

ID=25726135

Family Applications (1)

Application Number Title Priority Date Filing Date
CH221823D CH221823A (en) 1940-10-24 1940-10-24 Process for the preparation of a new benzimidazole derivative.

Country Status (1)

Country Link
CH (1) CH221823A (en)

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