CH182589A - Process for the preparation of a heterocyclic amino compound. - Google Patents
Process for the preparation of a heterocyclic amino compound.Info
- Publication number
- CH182589A CH182589A CH182589DA CH182589A CH 182589 A CH182589 A CH 182589A CH 182589D A CH182589D A CH 182589DA CH 182589 A CH182589 A CH 182589A
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- amino compound
- heterocyclic amino
- anilidobenzoxazole
- aniline
- Prior art date
Links
Description
Verfahren zur Herstellung einer heterocyclisghen Aminoverbindung. Vorliegendes Patent bezieht sich auf ein Verfahren zur Darstellung einer heterocy- clischen Aminoverbindung, dadurch gekenn zeichnet, dass man die Benzoxazol-2-sulfosäui#e mit Anilin umsetzt.
Das so gebildete 2-Anilidobenzoxazol zeigt di e in derLiteratur angegebenen Eigenschaften. Es soll als Zwischenprodukt zur Herstellung von Farbstoffen und pharmazeutischen Pro dukten Verwendung finden.
<I>Beispiel:</I> 3 kg 2-benzoxazolsulfosaures Natrium werden mit 1,5 kg Anilin in etwa 15 kg Wasser bei Zimmertemperatur gerührt. Es findet bereits bei 1#z-20 0 urfiter Temperatur steigerung die Umsetzung zum 2-Anilido- benzoxazol statt. Man rührt noch einige Stunden bei 40-50' nach. Der gebildete weisse Niederschlag wird abgesaugt, alkalisch gut gewaschen und gegebenenfalls durch Dampfdestillation oder Umkristallisieren von anhaftendem Anilin befreit.
Man erhält auf diese Weise in guter Ausbeute das 2-Anilido- benzoxazol, das nach dem Umkristallisieren aus z. B. Methanol in weissen Kristallen vom Schmelzpunkt 173-174' erhalten wird.
Process for the preparation of a heterocyclic amino compound. The present patent relates to a process for the preparation of a heterocyclic amino compound, characterized in that the benzoxazole-2-sulfo acid is reacted with aniline.
The 2-anilidobenzoxazole thus formed shows the properties reported in the literature. It is intended to be used as an intermediate in the manufacture of dyes and pharmaceutical products.
<I> Example: </I> 3 kg of 2-benzoxazolesulfonic acid are stirred with 1.5 kg of aniline in about 15 kg of water at room temperature. The conversion to 2-anilidobenzoxazole already takes place at a 1 ° z-20 ° increase in temperature. The mixture is stirred for a few hours at 40-50 '. The white precipitate formed is filtered off with suction, washed thoroughly under alkaline conditions and, if necessary, freed from adhering aniline by steam distillation or recrystallization.
In this way, 2-anilidobenzoxazole is obtained in good yield, which after recrystallization from z. B. methanol is obtained in white crystals of melting point 173-174 '.
Claims (1)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE182589X | 1933-10-07 | ||
| CH178536T | 1934-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH182589A true CH182589A (en) | 1936-02-15 |
Family
ID=25720140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH182589D CH182589A (en) | 1933-10-07 | 1934-04-26 | Process for the preparation of a heterocyclic amino compound. |
Country Status (1)
| Country | Link |
|---|---|
| CH (1) | CH182589A (en) |
-
1934
- 1934-04-26 CH CH182589D patent/CH182589A/en unknown
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