CH175920A - Process for the preparation of an aqueous solution of 3,6-diamino-10-methylacridinium palmitate. - Google Patents

Process for the preparation of an aqueous solution of 3,6-diamino-10-methylacridinium palmitate.

Info

Publication number
CH175920A
CH175920A CH175920DA CH175920A CH 175920 A CH175920 A CH 175920A CH 175920D A CH175920D A CH 175920DA CH 175920 A CH175920 A CH 175920A
Authority
CH
Switzerland
Prior art keywords
diamino
palmitate
aqueous solution
preparation
methylacridinium
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH175920A publication Critical patent/CH175920A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)

Description

  

  Verfahren zur Herstellung einer wässerigen Lösung von  3 .     6-Diamino-10-methylaeridiniumpalmitat.       Gegenstand der Erfindung ist ein Ver  fahren zur Herstellung einer wässerigen Lö  sung des     palmitinsauren    Salzes von     3.6-          Diamino-10-methylacridiniumehlorid,    welches  dadurch gekennzeichnet ist, dass man 3.6  Diamino-10-methylacridiniumpalmitat in Ge  genwart der durch Umsetzung von Ölsäure  ohlorid mit     oxyäthansulfonsaurem    Natrium  gewonnenen Verbindung in Wasser löst, wo  bei durch doppelte Umsetzung ein Gleich  gewicht zwischen beiden Verbindungen ein  tritt.  



  Die so erhaltene klare Lösung besitzt  wertvolle therapeutische     Eigenschaften    und  ist insbesondere zu Injektionszwecken ge  eignet.  



  <I>Beispiel:</I>  50     gr        3.6-Diaminomethylacridiniumpal-          mitat    werden in 1000     eins    3     o/oiger    Lösung  der nach dem französischen Patent<B>705,081</B>  durch Umsetzung von     Ölsäurechlorid    mit oxy-         äthansulfonsaurem        Natrium    gewonnenen Ver  bindung durch allmähliches Erwärmen gelöst.  Die Lösung lässt sich filtrieren und bleibt klar.



  Process for preparing an aqueous solution of 3. 6-diamino-10-methylaeridinium palmitate. The invention relates to a process for the production of an aqueous solution of the palmitic acid salt of 3.6-diamino-10-methylacridinium chloride, which is characterized in that one 3.6 diamino-10-methylacridinium palmitate in the presence of the by reaction of oleic acid with sodium oxyethanesulfonic acid The compound obtained dissolves in water, where an equilibrium between the two compounds occurs through double conversion.



  The clear solution thus obtained has valuable therapeutic properties and is particularly suitable for injection purposes.



  <I> Example: </I> 50 grams of 3.6-diaminomethylacridinium palmitate are added to 1000 liters of 3% solution of the compound obtained according to French patent <B> 705,081 </B> by reacting oleic acid chloride with sodium oxyethanesulfonic acid solved by gradually heating. The solution can be filtered and remains clear.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung einer wässeri gen Lösung von 3.6-Diamino-10-methylacri- diniumpalmitat, dadurch gekennzeichnet, dass man 3.6-Diamino-10-methylaeridiniumpalmi- tat in Gegenwart der durch Umsetzung von Ölsäurechlorid mit oxyäthansulfonsaurem Na trium gewonnenen Verbindung in Wasser löst, wobei durch doppelte Umsetzung ein Gleichgewicht zwischen beiden Verbindungen eintritt. Die so erhaltene klare Lösung besitzt wertvolle therapeutische Eigenschaften und ist insbesondere zu Injektionszwecken geeignet. PATENT CLAIM: Process for the preparation of an aqueous solution of 3.6-diamino-10-methylaeridinium palmitate, characterized in that 3.6-diamino-10-methylaeridinium palmitate is dissolved in water in the presence of the compound obtained by reacting oleic acid chloride with sodium oxyethanesulfonic acid , whereby an equilibrium occurs between the two compounds through double conversion. The clear solution obtained in this way has valuable therapeutic properties and is particularly suitable for injection purposes.
CH175920D 1931-12-16 1932-12-14 Process for the preparation of an aqueous solution of 3,6-diamino-10-methylacridinium palmitate. CH175920A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE175920X 1931-12-16
CH167954T 1932-12-14

Publications (1)

Publication Number Publication Date
CH175920A true CH175920A (en) 1935-03-15

Family

ID=25718489

Family Applications (1)

Application Number Title Priority Date Filing Date
CH175920D CH175920A (en) 1931-12-16 1932-12-14 Process for the preparation of an aqueous solution of 3,6-diamino-10-methylacridinium palmitate.

Country Status (1)

Country Link
CH (1) CH175920A (en)

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