CH156930A - Process for the preparation of a double compound of the pyridine series. - Google Patents

Process for the preparation of a double compound of the pyridine series.

Info

Publication number
CH156930A
CH156930A CH156930DA CH156930A CH 156930 A CH156930 A CH 156930A CH 156930D A CH156930D A CH 156930DA CH 156930 A CH156930 A CH 156930A
Authority
CH
Switzerland
Prior art keywords
preparation
double compound
pyridine
pyridine series
compound
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH156930A publication Critical patent/CH156930A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

  Verfahren zur Darstellung einer Doppelverbindung der     Pyridinreihe.       Es wurde gefunden, dass man zu einer  Doppelverbindung der     Pyridinreihe    gelangen  kann, wenn man 1     Mol        Nicotinsäureamid    auf  1     Mol        Calciumchlorid    einwirken lässt. Die  Reaktion kann in An- oder in Abwesenheit  eines Lösungsmittels ausgeführt werden.  



  Die neue Doppelverbindung bildet weisse  Kristalle. Sie ist in Wasser leicht löslich,  schwer löslich in Alkohol und unlöslich in  Aceton.  



  Das neue Produkt soll sowohl zur Ab  scheidung und Reinigung der zu Grunde  liegenden     Pyridinverbindung,    wie auch zu  therapeutischen Zwecken Verwendung finden.  <I>Beispiel:</I>  Eine alkoholische Lösung von 111 Teilen       Calciumchlorid    wird mit einer alkoholischen  Lösung von 122 Teilen     Nicotinsäureamid    ver  setzt. Nach kurzem Kochen am     Rückfluss     kristallisiert die neue Doppelverbindung aus.



  Process for the preparation of a double compound of the pyridine series. It has been found that a double compound of the pyridine series can be obtained if 1 mol of nicotinic acid amide is allowed to act on 1 mol of calcium chloride. The reaction can be carried out in the presence or in the absence of a solvent.



  The new double compound forms white crystals. It is easily soluble in water, sparingly soluble in alcohol and insoluble in acetone.



  The new product is intended to be used for separating and purifying the underlying pyridine compound as well as for therapeutic purposes. <I> Example: </I> An alcoholic solution of 111 parts of calcium chloride is combined with an alcoholic solution of 122 parts of nicotinic acid amide. After brief refluxing, the new double compound crystallizes out.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung einer Doppel verbindung der Pyridinreihe, dadurch gekenn zeichnet, dass man 111Io1 Nicotinsäureamid auf 1 Mol Caleiumchlorid einwirken lässt. Die neue Doppelverbindung bildet weisse Kristalle. Sie ist in Wasser leicht löslich, schwer löslich in Alkohol und unlöslich in Aceton. Das neue .Produkt soll sowohl zur Ab scheidung und Reinigung der zu Grunde lie genden Pyridinverbindung, wie auch zu the- rapeutischeii Zwecken Verwendung finden. PATENT CLAIM: Process for the preparation of a double compound of the pyridine series, characterized in that 111Io1 nicotinic acid amide is allowed to act on 1 mole of calcium chloride. The new double compound forms white crystals. It is easily soluble in water, sparingly soluble in alcohol and insoluble in acetone. The new .Product is intended to be used both for separating and purifying the underlying pyridine compound, as well as for therapeutic purposes. UNTERANSPRUCH: Verfahren nach Patentanspruch, dadurch gekennzeichnet, dass man die Reaktion in Gegenwart eines Lösungsmittels ausführt. SUBCLAIM: Process according to claim, characterized in that the reaction is carried out in the presence of a solvent.
CH156930D 1931-03-07 1931-03-07 Process for the preparation of a double compound of the pyridine series. CH156930A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH156930T 1931-03-07
CH154815T 1931-03-07

Publications (1)

Publication Number Publication Date
CH156930A true CH156930A (en) 1932-08-31

Family

ID=25716500

Family Applications (1)

Application Number Title Priority Date Filing Date
CH156930D CH156930A (en) 1931-03-07 1931-03-07 Process for the preparation of a double compound of the pyridine series.

Country Status (1)

Country Link
CH (1) CH156930A (en)

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