CH156939A - Process for the preparation of a double compound of the pyridine series. - Google Patents

Process for the preparation of a double compound of the pyridine series.

Info

Publication number
CH156939A
CH156939A CH156939DA CH156939A CH 156939 A CH156939 A CH 156939A CH 156939D A CH156939D A CH 156939DA CH 156939 A CH156939 A CH 156939A
Authority
CH
Switzerland
Prior art keywords
double compound
preparation
pyridine
pyridine series
compound
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH156939A publication Critical patent/CH156939A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)

Description

  

  Verfahren zur Darstellung einer Doppelverbindung der     Pyridinreihe.       Es wurde gefunden, dass man zu einer  Doppelverbindung der     Pyridinreihe    gelangen  kann, wenn man 2     Mol        a-Picolinsäurediäthyl-          amid    auf 1     Mol        Caleiumrhodanid    einwirken  lässt. Die Reaktion kann in An- oder Ab  wesenheit eines Lösungsmittels ausgeführt  werden.  



  Die neue Doppelverbindung bildet weisse  Kristalle. Sie ist in Wasser, Alkohol, Aceton  und Essigäther sehr leicht löslich.  



  Das neue Produkt soll sowohl zur Ab  scheidUng und Reinigung der zugrunde lie  genden     Pyridinverbindung,    wie auch zu thera  peutischen Zwecken Verwendung finden.  



  <I>Beispiel:</I>  23 Teile kristallwasserhaltiges     Calcium-          rhodanid,    entsprechend 15 Teilen wasserfreiem,  und 35 Teile     a-Picolinsäurediäthylamid    (was  serlösliches Öl, Kp. s 120      )    werden in Alko  hol gelöst. Nach kurzem Erhitzen auf dem  Wasserbad wird der Alkohol     abdestilliert,       wobei die gebildete Doppelverbindung als ein  fein kristallines, weisses Pulver zurückbleibt.



  Process for the preparation of a double compound of the pyridine series. It has been found that a double compound of the pyridine series can be obtained if 2 moles of a-picolinic acid diethyl amide are allowed to act on 1 mole of calcium rhodanide. The reaction can be carried out in the presence or absence of a solvent.



  The new double compound forms white crystals. It is very easily soluble in water, alcohol, acetone and vinegar ether.



  The new product is intended to be used for separating and purifying the underlying pyridine compound as well as for therapeutic purposes.



  <I> Example: </I> 23 parts of calcium rhodanide containing water of crystallization, corresponding to 15 parts of anhydrous, and 35 parts of a-picolinic acid diethylamide (soluble oil, b.p. s 120) are dissolved in alcohol. After brief heating on a water bath, the alcohol is distilled off, the double compound formed remaining as a finely crystalline, white powder.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung einer Doppel verbindung der Pyridinreihe, dadurch gekenn zeichnet, dass man 2 Mol a-Picolinsäurediäthyl- amid auf 1 Mol Calciumrhodanid einwirken lässt. Die neue Doppelverbindung bildet weisse Kristalle. Sie ist in Wasser, Alkohol, Aceton und Essigäther sehr leicht löslich. Das neue Produkt soll sowohl zur Ab scheidung und Reinigung der zugrunde lie genden Pyridinverbindung, wie auch zu thera peutischen Zwecken Verwendung finden. UNTERANSPRUCH: Verfahren nach Patentanspruch, dadurch gekennzeichnet, dass man die Reaktion in Gegenwart eines Lösungsmittels ausführt. PATENT CLAIM: Process for the preparation of a double compound of the pyridine series, characterized in that 2 moles of a-picolinic acid diethyl amide are allowed to act on 1 mole of calcium rhodanide. The new double compound forms white crystals. It is very easily soluble in water, alcohol, acetone and vinegar ether. The new product is intended to be used both for separating and purifying the underlying pyridine compound as well as for therapeutic purposes. SUBCLAIM: Process according to claim, characterized in that the reaction is carried out in the presence of a solvent.
CH156939D 1931-03-07 1931-03-07 Process for the preparation of a double compound of the pyridine series. CH156939A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH156939T 1931-03-07
CH154815T 1931-03-07

Publications (1)

Publication Number Publication Date
CH156939A true CH156939A (en) 1932-08-31

Family

ID=25716509

Family Applications (1)

Application Number Title Priority Date Filing Date
CH156939D CH156939A (en) 1931-03-07 1931-03-07 Process for the preparation of a double compound of the pyridine series.

Country Status (1)

Country Link
CH (1) CH156939A (en)

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