CH156929A - Process for the preparation of a double compound of the pyridine series. - Google Patents

Process for the preparation of a double compound of the pyridine series.

Info

Publication number
CH156929A
CH156929A CH156929DA CH156929A CH 156929 A CH156929 A CH 156929A CH 156929D A CH156929D A CH 156929DA CH 156929 A CH156929 A CH 156929A
Authority
CH
Switzerland
Prior art keywords
double compound
preparation
pyridine
pyridine series
compound
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH156929A publication Critical patent/CH156929A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

  Verfahren zur Darstellung einer Doppelverbindung der     Pyizdinreihe.       Es wurde gefunden, dass man zu einer  Doppelverbindung der     Pyridinreihe    gelangen  kann, wenn man 1     Mol        Nicotinsäureäthylester     auf 1     Mol        Calciumchlorid        einwirken    lässt. Die  Reaktion kann in An- oder in Abwesenheit  eines Lösungsmittels ausgeführt werden.  



  Die neue Doppelverbindung bildet weisse  Kristalle. Sie ist in Alkohol löslich, schwer  löslich in Essigäther und unlöslich in Aceton.  



  Das neue Produkt soll sowohl zur Ab  scheidung und Reinigung der zu Grunde lie  genden     Pyridinverbindung,    wie auch zu the  rapeutischen Zwecken Verwendung finden.  



  <I>Beispiel:</I>  151 Teile     Nicotinsäureäthylester    werden  zu einer Lösung von 111 Teilen     Calcium-          chlorid    in 500 Teilen Alkohol gegeben. Nach  kurzem Erwärmen kristallisiert die neue  Doppelverbindung aus.



  Process for the preparation of a double compound of the pyizdine series. It has been found that a double compound of the pyridine series can be obtained if 1 mol of ethyl nicotinate is allowed to act on 1 mol of calcium chloride. The reaction can be carried out in the presence or in the absence of a solvent.



  The new double compound forms white crystals. It is soluble in alcohol, sparingly soluble in vinegar and insoluble in acetone.



  The new product is intended to be used both for separating and cleaning the underlying pyridine compound, as well as for therapeutic purposes.



  <I> Example: </I> 151 parts of ethyl nicotinate are added to a solution of 111 parts of calcium chloride in 500 parts of alcohol. The new double compound crystallizes out after brief heating.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung einer Doppel verbindung der Pyridinreihe, dadurch gekenn zeichnet, dass man 1 Hol Nicotinsäureäthyl- ester auf 1 Mol Calciumchlorid einwirken lässt. Die neue Doppelverbindung bildet weisse Kristalle. Sie ist in Alkohol löslich, schwer löslich in Essigäther und unlöslich in Aceton. Das neue Produkt soll sowohl zur Ab scheidung und Reinigung der zu Grunde lie genden Pyridinverbinduug, wie auch zu the rapeutischen Zwecken Verwendung finden. PATENT CLAIM: Process for the production of a double compound of the pyridine series, characterized in that 1 hol of ethyl nicotinate is allowed to act on 1 mol of calcium chloride. The new double compound forms white crystals. It is soluble in alcohol, sparingly soluble in vinegar and insoluble in acetone. The new product is to be used both for separating and cleaning the underlying pyridine compound, as well as for therapeutic purposes. UNTERANSPRUCH: Verfahren nach Patentanspruch, dadurch gekennzeichnet, dass man die Reaktion in Gegenwart eines Lösungsmittels ausführt. SUBCLAIM: Process according to claim, characterized in that the reaction is carried out in the presence of a solvent.
CH156929D 1931-03-07 1931-03-07 Process for the preparation of a double compound of the pyridine series. CH156929A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH154815T 1931-03-07
CH156929T 1931-03-07

Publications (1)

Publication Number Publication Date
CH156929A true CH156929A (en) 1932-08-31

Family

ID=25716499

Family Applications (1)

Application Number Title Priority Date Filing Date
CH156929D CH156929A (en) 1931-03-07 1931-03-07 Process for the preparation of a double compound of the pyridine series.

Country Status (1)

Country Link
CH (1) CH156929A (en)

Similar Documents

Publication Publication Date Title
CH156929A (en) Process for the preparation of a double compound of the pyridine series.
CH156930A (en) Process for the preparation of a double compound of the pyridine series.
CH156933A (en) Process for the preparation of a double compound of the pyridine series.
CH154815A (en) Process for the preparation of a double compound of the pyridine series.
CH156938A (en) Process for the preparation of a double compound of the pyridine series.
CH156935A (en) Process for the preparation of a double compound of the pyridine series.
CH156937A (en) Process for the preparation of a double compound of the pyridine series.
CH156934A (en) Process for the preparation of a double compound of the pyridine series.
CH156936A (en) Process for the preparation of a double compound of the pyridine series.
CH156932A (en) Process for the preparation of a double compound of the pyridine series.
CH156939A (en) Process for the preparation of a double compound of the pyridine series.
CH156931A (en) Process for the preparation of a double compound of the pyridine series.
CH161482A (en) Process for the preparation of 2-methyl-B-naphthindole-5-sulfonic acid.
CH174910A (en) Process for the preparation of the salt of 2,3-dimethoxy-6-nitro-9- (ydiäthylamino-B-oxy-propylamino) -acridine with 2-methyl-4-glycolylaminobenzene-1-arsic acid.
CH139407A (en) Process for the preparation of 3,6-diamino-10-methylacridinium deoxycholate.
CH191341A (en) Process for the preparation of a theophylline derivative of a urethane series mercury compound.
CH192777A (en) Process for the preparation of a substituted pyridine-o-dicarboxamide.
CH192780A (en) Process for the preparation of a substituted pyridine-o-dicarboxamide.
CH192779A (en) Process for the preparation of a substituted pyridine-o-dicarboxamide.
CH174886A (en) Process for the preparation of an oxycarboxylic acid.
CH139448A (en) Process for the preparation of a basic derivative of a substituted quinoline carboxylic acid.
CH174911A (en) Process for the preparation of the salt of 2,3-dimethoxy-6-nitro-9- (γ-diethylamino-B-oxy-propylamino) -acridine with 3-acetylamino-4-oxybenzene-1-arsic acid.
CH297734A (en) Process for the preparation of a new quaternary salt.
CH195562A (en) Process for the preparation of a theophylline derivative of a urethane series mercury compound.
CH243013A (en) Process for the preparation of a p-amino-benzenesulfonacylamide.