CH149013A - Process for the preparation of an N-substituted compound of the pyridone series. - Google Patents

Process for the preparation of an N-substituted compound of the pyridone series.

Info

Publication number
CH149013A
CH149013A CH149013DA CH149013A CH 149013 A CH149013 A CH 149013A CH 149013D A CH149013D A CH 149013DA CH 149013 A CH149013 A CH 149013A
Authority
CH
Switzerland
Prior art keywords
preparation
substituted compound
pyridone
pyridone series
series
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH149013A publication Critical patent/CH149013A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Description

  

  Verfahren zur Darstellung einer     N-substituierten    Verbindung der     Pyridonreihe.       Es wurde gefunden, dass man zu einer       N-substituierten    Verbindung der     Pyridonreihe     gelangen kann, wenn man     2-Diäthylamino-          äthogypyridin-5-carbonsäLrreanilid_    durch Er  wärmen umlagert.  



  Das entstandene     N-Diäthylaminoäthyl-2-          pyridon-5-carbonsäureanilid    schmilzt bei 102  .  Es ist in organischen Lösungsmitteln, sowie  in     Säuren    löslich.  



  Die neue Base soll für therapeutische  Zwecke Verwendung finden.    <I>Beispiel:</I>  2 -     Diäthyläminoätlroxypyridin    - 5 -     carbon-          säureanilid    wird durch Erhitzen auf etwa  220-270<B>0</B> umgelagert.



  Process for the preparation of an N-substituted compound of the pyridone series. It has been found that an N-substituted compound of the pyridone series can be obtained if 2-diethylamino-äthogypyridin-5-carbonsäLrreanilid_ is rearranged by warming it.



  The resulting N-diethylaminoethyl-2-pyridone-5-carboxylic acid anilide melts at 102. It is soluble in organic solvents as well as acids.



  The new base will be used for therapeutic purposes. <I> Example: </I> 2 - diethylaminoethyloxypyridine - 5 - carboxylic acid anilide is rearranged by heating to around 220-270 <B> 0 </B>.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung einer N-substi- tuierten Verbindung der Pyridonreihe, da durch gekennzeichnet, dass man 2-Diäthyl- aminoäthoxypyridin-5-carbonsäureanilid durch Erwärmen umlagert. Das entstandene N-Diäthylaminoäthyl-2- pyridon-5-carbonsäureanilid schmilzt bei 1021. Es ist in organischen Lösungsmitteln, sowie in Säuren löslich. Die neue Base soll für therapeutische Zwecke Verwendung finden. PATENT CLAIM: Process for the preparation of an N-substituted compound of the pyridone series, characterized in that 2-diethylaminoethoxypyridine-5-carboxylic acid anilide is rearranged by heating. The resulting N-diethylaminoethyl-2-pyridone-5-carboxylic acid anilide melts at 1021. It is soluble in organic solvents and acids. The new base will be used for therapeutic purposes.
CH149013D 1929-08-10 1929-08-10 Process for the preparation of an N-substituted compound of the pyridone series. CH149013A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH146709T 1929-08-10
CH149013T 1929-08-10

Publications (1)

Publication Number Publication Date
CH149013A true CH149013A (en) 1931-08-15

Family

ID=25714916

Family Applications (1)

Application Number Title Priority Date Filing Date
CH149013D CH149013A (en) 1929-08-10 1929-08-10 Process for the preparation of an N-substituted compound of the pyridone series.

Country Status (1)

Country Link
CH (1) CH149013A (en)

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