CH149009A - Process for the preparation of an N-substituted compound of the pyridone series. - Google Patents

Process for the preparation of an N-substituted compound of the pyridone series.

Info

Publication number
CH149009A
CH149009A CH149009DA CH149009A CH 149009 A CH149009 A CH 149009A CH 149009D A CH149009D A CH 149009DA CH 149009 A CH149009 A CH 149009A
Authority
CH
Switzerland
Prior art keywords
preparation
substituted compound
pyridone series
pyridone
series
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH149009A publication Critical patent/CH149009A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

  Verfahren zur Darstellung einer     N-substituierten    Verbindung der     Pyridonreihe.       Es wurde gefunden, dass man zu einer       N-substituierten    Verbindung der     Pyridonreihe     gelangen kann, wenn man     2-Diäthylamino-          äthoxylepidin    durch Erwärmen umlagert.  



  Das entstandene     N-Diäthylaminoäthyl-          lepidon    siedet bei 183   unter 2 mm Druck;  es ist in organischen Lösungsmitteln, sowie  in Säuren löslich. Sein     Monochlorhydrat     schmilzt bei 115   und löst sich leicht in  Wasser.  



  Die neue Base soll für therapeutische  Zwecke Verwendung finden.  



  <I>Beispiel:</I>       2-Diäthylamiiioäthoxylepidin    wird     durch     Erhitzen auf 220<B>0</B> bis 270<B>0</B> umgelagert.



  Process for the preparation of an N-substituted compound of the pyridone series. It has been found that an N-substituted compound of the pyridone series can be obtained if 2-diethylamino ethoxylepidine is rearranged by heating.



  The resulting N-diethylaminoethyl lepidone boils at 183 under 2 mm pressure; it is soluble in organic solvents as well as acids. Its monochlorohydrate melts at 115 and easily dissolves in water.



  The new base will be used for therapeutic purposes.



  <I> Example: </I> 2-diethylamiiioethoxylepidine is rearranged by heating to 220 <B> 0 </B> to 270 <B> 0 </B>.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung einer N-sub- stituierten Verbindung der Pyridonreihe, da durch gekennzeichnet, dass man 2-Diäthyl- aminoäthoxylepidin durch Erwärmen um lagert. PATENT CLAIM: Process for the preparation of an N-substituted compound of the pyridone series, characterized in that 2-diethylaminoethoxylepidine is rearranged by heating. Das entstandene N-Diäthylaminoäthyl- lepidon siedet bei<B>1830</B> unter 2 min Druck es ist in organischen Lösungsmitteln, sowie in Säuren löslich. Sein Monochlorhydrat schmilzt bei 115 und löst sich leicht in Wasser. Die neue Base soll für therapeutische Zwecke Verwendung finden. The resulting N-diethylaminoethyl lepidone boils at <B> 1830 </B> under 2 minutes of pressure and is soluble in organic solvents and acids. Its monochlorohydrate melts at 115 and easily dissolves in water. The new base will be used for therapeutic purposes.
CH149009D 1929-08-10 1929-08-10 Process for the preparation of an N-substituted compound of the pyridone series. CH149009A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH146709T 1929-08-10
CH149009T 1929-08-10

Publications (1)

Publication Number Publication Date
CH149009A true CH149009A (en) 1931-08-15

Family

ID=25714912

Family Applications (1)

Application Number Title Priority Date Filing Date
CH149009D CH149009A (en) 1929-08-10 1929-08-10 Process for the preparation of an N-substituted compound of the pyridone series.

Country Status (1)

Country Link
CH (1) CH149009A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2372810A1 (en) * 1976-03-09 1978-06-30 Boehringer Sohn Ingelheim NEW AMINOALCOYLIMIDAZOLIDINONES, METHODS FOR THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2372810A1 (en) * 1976-03-09 1978-06-30 Boehringer Sohn Ingelheim NEW AMINOALCOYLIMIDAZOLIDINONES, METHODS FOR THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS

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