CA994242A - Compositions containing substituted benzoylpropionic acids and method of use - Google Patents

Compositions containing substituted benzoylpropionic acids and method of use

Info

Publication number
CA994242A
CA994242A CA120,550A CA120550A CA994242A CA 994242 A CA994242 A CA 994242A CA 120550 A CA120550 A CA 120550A CA 994242 A CA994242 A CA 994242A
Authority
CA
Canada
Prior art keywords
compositions containing
containing substituted
benzoylpropionic acids
substituted benzoylpropionic
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA120,550A
Other languages
English (en)
Other versions
CA120550S (en
Inventor
Andrew S. Tomcufcik
Ralph G. Child
Adolph E. Sloboda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22117783&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA994242(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of CA994242A publication Critical patent/CA994242A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA120,550A 1970-09-21 1971-08-13 Compositions containing substituted benzoylpropionic acids and method of use Expired CA994242A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7410870A 1970-09-21 1970-09-21

Publications (1)

Publication Number Publication Date
CA994242A true CA994242A (en) 1976-08-03

Family

ID=22117783

Family Applications (1)

Application Number Title Priority Date Filing Date
CA120,550A Expired CA994242A (en) 1970-09-21 1971-08-13 Compositions containing substituted benzoylpropionic acids and method of use

Country Status (11)

Country Link
US (1) US3784701A (fr)
BE (1) BE772804A (fr)
CA (1) CA994242A (fr)
DE (1) DE2147111C3 (fr)
ES (1) ES395257A0 (fr)
FR (1) FR2107848B1 (fr)
GB (1) GB1320076A (fr)
IL (1) IL37637A (fr)
MY (1) MY7500135A (fr)
NL (1) NL175788C (fr)
ZA (1) ZA714252B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1498903A (en) * 1974-03-25 1978-01-25 Fabre Sa Pierre Aromatic keto-acids and their derivatives
US3966960A (en) * 1975-04-25 1976-06-29 American Cyanamid Company 3-(4-Biphenylcarbonyl)propionic acid as an inhibitor of platelet aggregation
US4247466A (en) * 1979-07-05 1981-01-27 American Cyanamid Company Lactone metabolites of 3-(4-biphenylylcarbonyl)propionic acid
US4782089A (en) * 1986-08-26 1988-11-01 A. H. Robins Company, Incorporated 2-amino-3-aroyl-gamma-oxobenzenebutanoic acids and esters
US5280045A (en) * 1991-10-16 1994-01-18 The Procter & Gamble Company 4(3,5-bis(1,1-dimethylethyl-4-hydroxyphenyl)-4-oxobutanamide compound useful as an anti-inflammatory agent
US5789434A (en) * 1994-11-15 1998-08-04 Bayer Corporation Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
AR002945A1 (es) * 1994-11-15 1998-05-27 Bayer Corp Acidos 4-biarilbutirico o 5-biarilpentanoico sustituidos y sus derivados como inhibidores de las metaloproteasas de matriz, composicion que los contiene, y metodos para la preparacion de dichos compuestos
US5886022A (en) * 1995-06-05 1999-03-23 Bayer Corporation Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors
US5684204A (en) * 1995-11-15 1997-11-04 The Procter & Gamble Company Sulfur containing di-tert-butylphenol compounds useful as anti-inflammatory agents
CZ298814B6 (cs) 1996-01-23 2008-02-13 Shionogi & Co., Ltd. Sulfonované deriváty aminokyselin a metaloproteasové inhibitory obsahující tyto deriváty
US6919375B1 (en) * 1996-01-23 2005-07-19 Shionogi & Co., Ltd. Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same
US5968795A (en) * 1996-05-15 1999-10-19 Bayer Corporation Biaryl acetylenes as inhibitors of matrix metalloproteases
HRP970243B1 (en) * 1996-05-15 2002-06-30 Bayer Ag Inhibition of matrix metalloproteases by substituted phenethyl compounds
CO5080759A1 (es) * 1996-05-15 2001-09-25 Bayer Corp Biarilacetilenos como inhibidores de la metaloproteasa de matriz
IT1288123B1 (it) * 1996-09-04 1998-09-10 Nicox Sa Uso di nitroderivati per l'incontinenza urinaria
SI0946166T1 (en) * 1996-12-17 2004-06-30 Warner-Lambert Company Llc Use of matrix metalloproteinase inhibitors for promoting wound healing
PT946166E (pt) * 1996-12-17 2004-06-30 Warner Lambert Co Utilizacao de inibidores das metaloproteinases da matriz para tratar disturbios neurologicos e promover a cicatrizacao de feridas
US5756545A (en) * 1997-04-21 1998-05-26 Warner-Lambert Company Biphenysulfonamide matrix metal alloproteinase inhibitors
IT1308633B1 (it) 1999-03-02 2002-01-09 Nicox Sa Nitrossiderivati.
IT1318674B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Faramaci per l'incontinenza.
IT1318673B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Farmaci per le disfunzioni sessuali.
FR2832925B1 (fr) * 2001-12-03 2006-07-14 Lipha Utilisation de derives de l'acide 4-oxobutanoique dans le traitement de l'inflammation
ITMI20020773A1 (it) * 2002-04-11 2003-10-13 Nicox Sa Farmaci per il trattamento dell'artrite
US20040234701A1 (en) * 2003-02-19 2004-11-25 Caton Gregory James Lower alkyl carboxylic acid moieties as organoleptic stabilizers and preservatives of food and beverages and for preventing oxidative corrosion of metals
AU2005249410A1 (en) * 2004-05-14 2005-12-15 Emisphere Technologies, Inc. Aryl ketone compounds and compositions for delivering active agents
AU2010233089B2 (en) 2009-04-10 2016-05-26 Tufts Medical Center, Inc. Par-1 activation by metalloproteinase-1 (MMP-1)

Also Published As

Publication number Publication date
MY7500135A (en) 1975-12-31
GB1320076A (en) 1973-06-13
ZA714252B (en) 1972-03-29
IL37637A0 (en) 1971-11-29
FR2107848A1 (fr) 1972-05-12
DE2147111A1 (de) 1972-03-23
ES9000032A1 (es) 1975-01-01
DE2147111B2 (de) 1979-05-10
NL7110996A (fr) 1972-03-23
ES395257A0 (es) 1975-01-01
IL37637A (en) 1974-06-30
FR2107848B1 (fr) 1975-08-01
NL175788C (nl) 1985-01-02
DE2147111C3 (de) 1980-01-31
US3784701A (en) 1974-01-08
NL175788B (nl) 1984-08-01
BE772804A (fr) 1972-03-20

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