CA994242A - Compositions containing substituted benzoylpropionic acids and method of use - Google Patents

Compositions containing substituted benzoylpropionic acids and method of use

Info

Publication number
CA994242A
CA994242A CA120,550A CA120550A CA994242A CA 994242 A CA994242 A CA 994242A CA 120550 A CA120550 A CA 120550A CA 994242 A CA994242 A CA 994242A
Authority
CA
Canada
Prior art keywords
compositions containing
containing substituted
benzoylpropionic acids
substituted benzoylpropionic
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA120,550A
Other languages
English (en)
Other versions
CA120550S (en
Inventor
Andrew S. Tomcufcik
Ralph G. Child
Adolph E. Sloboda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22117783&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA994242(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of CA994242A publication Critical patent/CA994242A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA120,550A 1970-09-21 1971-08-13 Compositions containing substituted benzoylpropionic acids and method of use Expired CA994242A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7410870A 1970-09-21 1970-09-21

Publications (1)

Publication Number Publication Date
CA994242A true CA994242A (en) 1976-08-03

Family

ID=22117783

Family Applications (1)

Application Number Title Priority Date Filing Date
CA120,550A Expired CA994242A (en) 1970-09-21 1971-08-13 Compositions containing substituted benzoylpropionic acids and method of use

Country Status (11)

Country Link
US (1) US3784701A (fr)
BE (1) BE772804A (fr)
CA (1) CA994242A (fr)
DE (1) DE2147111C3 (fr)
ES (1) ES9000032A1 (fr)
FR (1) FR2107848B1 (fr)
GB (1) GB1320076A (fr)
IL (1) IL37637A (fr)
MY (1) MY7500135A (fr)
NL (1) NL175788C (fr)
ZA (1) ZA714252B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4008323A (en) * 1974-03-25 1977-02-15 Pierre Fabre S.A. Method of reducing cholesterol using certain aromatic keto acids
US3966960A (en) * 1975-04-25 1976-06-29 American Cyanamid Company 3-(4-Biphenylcarbonyl)propionic acid as an inhibitor of platelet aggregation
US4247466A (en) * 1979-07-05 1981-01-27 American Cyanamid Company Lactone metabolites of 3-(4-biphenylylcarbonyl)propionic acid
US4782089A (en) * 1986-08-26 1988-11-01 A. H. Robins Company, Incorporated 2-amino-3-aroyl-gamma-oxobenzenebutanoic acids and esters
US5280045A (en) * 1991-10-16 1994-01-18 The Procter & Gamble Company 4(3,5-bis(1,1-dimethylethyl-4-hydroxyphenyl)-4-oxobutanamide compound useful as an anti-inflammatory agent
US5789434A (en) * 1994-11-15 1998-08-04 Bayer Corporation Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
AR002945A1 (es) * 1994-11-15 1998-05-27 Bayer Corp Acidos 4-biarilbutirico o 5-biarilpentanoico sustituidos y sus derivados como inhibidores de las metaloproteasas de matriz, composicion que los contiene, y metodos para la preparacion de dichos compuestos
US5886022A (en) * 1995-06-05 1999-03-23 Bayer Corporation Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors
US5684204A (en) * 1995-11-15 1997-11-04 The Procter & Gamble Company Sulfur containing di-tert-butylphenol compounds useful as anti-inflammatory agents
TR199801419T2 (xx) 1996-01-23 1998-10-21 Shionogi & Co.Ltd. S�lfone amino asit t�revleri ve ayn� i�erikte metaloproteinez �nleyicileri.
US6919375B1 (en) * 1996-01-23 2005-07-19 Shionogi & Co., Ltd. Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same
ZA974029B (en) * 1996-05-15 1998-02-19 Bayer Ag Inhibition of matrix metalloproteinases by substituted phenethyl compounds.
ZA974031B (en) * 1996-05-15 1998-02-19 Bayer Ag Biaryl acetylenes as inhibitors of matrix metalloproteases.
US5968795A (en) * 1996-05-15 1999-10-19 Bayer Corporation Biaryl acetylenes as inhibitors of matrix metalloproteases
IT1288123B1 (it) * 1996-09-04 1998-09-10 Nicox Sa Uso di nitroderivati per l'incontinenza urinaria
EP1366765A1 (fr) * 1996-12-17 2003-12-03 Warner-Lambert Company Llc Utilisation d'inhibiteurs de métalloproteinase matricielle dans le traitement de maladies neurologiques et la cicatrisation des blessures
JP2001507342A (ja) * 1996-12-17 2001-06-05 ワーナー−ランバート・コンパニー 神経疾患の治療および創傷治癒を促進するためのマトリックスメタロプロテイナーゼ阻害剤の使用
US5756545A (en) * 1997-04-21 1998-05-26 Warner-Lambert Company Biphenysulfonamide matrix metal alloproteinase inhibitors
IT1308633B1 (it) 1999-03-02 2002-01-09 Nicox Sa Nitrossiderivati.
IT1318674B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Faramaci per l'incontinenza.
IT1318673B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Farmaci per le disfunzioni sessuali.
FR2832925B1 (fr) * 2001-12-03 2006-07-14 Lipha Utilisation de derives de l'acide 4-oxobutanoique dans le traitement de l'inflammation
ITMI20020773A1 (it) * 2002-04-11 2003-10-13 Nicox Sa Farmaci per il trattamento dell'artrite
WO2004074547A2 (fr) * 2003-02-19 2004-09-02 Intellectual Concepts, Llc Fractions d'acide carboxylique renfermant un alkyle inferieur utilisees comme stabilisateurs et conservateurs organoleptiques pour aliments et boissons et permettant d'empecher la corrosion par oxydation des metaux
JP4995080B2 (ja) * 2004-05-14 2012-08-08 エミスフェアー・テクノロジーズ・インク 活性薬剤を送達するためのアリールケトン化合物および組成物
WO2010118435A2 (fr) 2009-04-10 2010-10-14 Tufts Medical Center, Inc. Activation de par-1 par la métalloprotéinase-1 (mmp-1)

Also Published As

Publication number Publication date
MY7500135A (en) 1975-12-31
IL37637A (en) 1974-06-30
DE2147111C3 (de) 1980-01-31
ZA714252B (en) 1972-03-29
FR2107848B1 (fr) 1975-08-01
FR2107848A1 (fr) 1972-05-12
NL7110996A (fr) 1972-03-23
BE772804A (fr) 1972-03-20
NL175788C (nl) 1985-01-02
ES395257A0 (es) 1975-01-01
IL37637A0 (en) 1971-11-29
ES9000032A1 (es) 1975-01-01
DE2147111A1 (de) 1972-03-23
DE2147111B2 (de) 1979-05-10
US3784701A (en) 1974-01-08
NL175788B (nl) 1984-08-01
GB1320076A (en) 1973-06-13

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