CA981265A - 3-amino-1,2,4-benzotriazine-1,4-di-n-oxides and processes for their preparation and use - Google Patents
3-amino-1,2,4-benzotriazine-1,4-di-n-oxides and processes for their preparation and useInfo
- Publication number
- CA981265A CA981265A CA162,047A CA162047A CA981265A CA 981265 A CA981265 A CA 981265A CA 162047 A CA162047 A CA 162047A CA 981265 A CA981265 A CA 981265A
- Authority
- CA
- Canada
- Prior art keywords
- benzotriazine
- oxides
- amino
- processes
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
- C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/168—Steroids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/184—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Fodder In General (AREA)
- Plural Heterocyclic Compounds (AREA)
- Crushing And Grinding (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2204574A DE2204574A1 (de) | 1972-02-01 | 1972-02-01 | Verfahren zur herstellung von 3-aminobenzo-1,2,4-triazin-di-n-oxiden (1,4) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA981265A true CA981265A (en) | 1976-01-06 |
Family
ID=5834640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA162,047A Expired CA981265A (en) | 1972-02-01 | 1973-01-25 | 3-amino-1,2,4-benzotriazine-1,4-di-n-oxides and processes for their preparation and use |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US3868371A (ro) |
| JP (2) | JPS4882017A (ro) |
| AR (1) | AR193463A1 (ro) |
| AT (1) | AT322559B (ro) |
| AU (1) | AU464773B2 (ro) |
| BE (1) | BE794742A (ro) |
| BG (1) | BG22396A3 (ro) |
| CA (1) | CA981265A (ro) |
| CH (1) | CH576458A5 (ro) |
| CS (1) | CS183675B2 (ro) |
| DD (1) | DD103897A5 (ro) |
| DE (1) | DE2204574A1 (ro) |
| DK (1) | DK132408C (ro) |
| ES (1) | ES411154A1 (ro) |
| FR (1) | FR2181701B1 (ro) |
| GB (1) | GB1373324A (ro) |
| GT (1) | GT198062785A (ro) |
| HU (1) | HU165299B (ro) |
| IE (1) | IE37169B1 (ro) |
| IL (1) | IL41426A (ro) |
| LU (1) | LU66931A1 (ro) |
| NL (1) | NL7301245A (ro) |
| NO (1) | NO136096C (ro) |
| PL (1) | PL79604B1 (ro) |
| RO (1) | RO62861A (ro) |
| SE (1) | SE393612B (ro) |
| SU (1) | SU505329A3 (ro) |
| ZA (1) | ZA73702B (ro) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3991189A (en) * | 1972-11-15 | 1976-11-09 | Bayer Aktiengesellschaft | Microbiocidal methods and compositions using substituted 1,2,4-triazine-1,4-di-N-oxide derivatives |
| SE7501624L (ro) * | 1974-03-15 | 1975-09-16 | Ciba Geigy Ag | |
| US4247691A (en) * | 1977-02-22 | 1981-01-27 | Ciba-Geigy Corporation | 1,2,4-Benzotriazine-1,4-di-N-oxides |
| SU997646A1 (ru) * | 1978-11-27 | 1983-02-23 | Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвсср | Кормова добавка |
| US5175287A (en) * | 1986-09-25 | 1992-12-29 | S R I International | Process for preparing 1,2,4-benzotriazine oxides |
| US5624925A (en) * | 1986-09-25 | 1997-04-29 | Sri International | 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents |
| DE68929050T2 (de) | 1989-09-18 | 2000-02-03 | Stanford Res Inst Int | 1,2,4-benzotriazinoxide als funkempfindliche und selektive zytotoxische mittel |
| US5672702A (en) * | 1995-12-04 | 1997-09-30 | Sanofi | Process for preparing 3 amino 1, 2, 4-benzotriazine dioxide |
| JP2005509033A (ja) * | 2001-11-13 | 2005-04-07 | サノフィ−シンテラボ | ３−アミノ−１，２，４−ベンゾトリアジンジオキドを調製する方法 |
| US20090136521A1 (en) * | 2005-10-03 | 2009-05-28 | Genetix Pharmaceuticals , Inc. | Method for Selectively Depleting Hypoxic Cells |
| WO2008033466A2 (en) * | 2006-09-14 | 2008-03-20 | Combinatorx (Singapore) Pre. Ltd. | Compositions and methods for treatment of viral diseases |
| US20090076011A1 (en) * | 2007-09-19 | 2009-03-19 | Protia, Llc | Deuterium-enriched tirapazamine |
| CN104105692B (zh) | 2011-12-07 | 2016-06-29 | 思研（Sri）国际顾问与咨询公司 | 作为结核分枝杆菌靶向药物的苯并三嗪氧化物 |
| CN102603783B (zh) * | 2012-03-16 | 2014-09-03 | 张俏男 | 一种靶向抗恶性肿瘤的药物及其制备方法 |
| EP4201403A1 (en) | 2021-12-21 | 2023-06-28 | Som Innovation Biotech, S.L. | Compounds tirapazamine and quazinone for use in the treatment of gm2 gangliosidoses |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1007331A (en) * | 1960-12-01 | 1965-10-13 | Fisons Pest Control Ltd | Quinazolin-3-oxides and benzo-1,2,3-triazine-3-oxides |
-
0
- BE BE794742D patent/BE794742A/xx unknown
-
1972
- 1972-02-01 DE DE2204574A patent/DE2204574A1/de active Pending
-
1973
- 1973-01-17 RO RO7300073521A patent/RO62861A/ro unknown
- 1973-01-24 US US326389A patent/US3868371A/en not_active Expired - Lifetime
- 1973-01-25 CA CA162,047A patent/CA981265A/en not_active Expired
- 1973-01-27 BG BG22548A patent/BG22396A3/xx unknown
- 1973-01-29 JP JP48011241A patent/JPS4882017A/ja active Pending
- 1973-01-29 JP JP48011240A patent/JPS4881881A/ja active Pending
- 1973-01-29 NL NL7301245A patent/NL7301245A/xx not_active Application Discontinuation
- 1973-01-30 CH CH129073A patent/CH576458A5/xx not_active IP Right Cessation
- 1973-01-30 IL IL41426A patent/IL41426A/en unknown
- 1973-01-30 LU LU66931A patent/LU66931A1/xx unknown
- 1973-01-30 AT AT80573A patent/AT322559B/de not_active IP Right Cessation
- 1973-01-31 AU AU51620/73A patent/AU464773B2/en not_active Expired
- 1973-01-31 GB GB485373A patent/GB1373324A/en not_active Expired
- 1973-01-31 ES ES411154A patent/ES411154A1/es not_active Expired
- 1973-01-31 NO NO400/73A patent/NO136096C/no unknown
- 1973-01-31 DD DD168604A patent/DD103897A5/xx unknown
- 1973-01-31 CS CS7300000749A patent/CS183675B2/cs unknown
- 1973-01-31 PL PL1973160492A patent/PL79604B1/pl unknown
- 1973-01-31 SE SE7301341A patent/SE393612B/xx unknown
- 1973-01-31 ZA ZA730702A patent/ZA73702B/xx unknown
- 1973-01-31 IE IE155/73A patent/IE37169B1/xx unknown
- 1973-01-31 DK DK53373*#A patent/DK132408C/da active
- 1973-02-01 FR FR7303557A patent/FR2181701B1/fr not_active Expired
- 1973-02-01 AR AR246389A patent/AR193463A1/es active
- 1973-02-01 SU SU1979322A patent/SU505329A3/ru active
- 1973-02-01 HU HUBA2859A patent/HU165299B/hu unknown
-
1980
- 1980-03-28 GT GT198062785A patent/GT198062785A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE37169B1 (en) | 1977-05-25 |
| HU165299B (ro) | 1974-08-28 |
| FR2181701B1 (ro) | 1976-10-22 |
| BG22396A3 (ro) | 1977-02-20 |
| FR2181701A1 (ro) | 1973-12-07 |
| SU505329A3 (ru) | 1976-02-28 |
| AT322559B (de) | 1975-05-26 |
| IL41426A (en) | 1976-06-30 |
| JPS4881881A (ro) | 1973-11-01 |
| NO136096C (no) | 1977-07-20 |
| DK132408B (da) | 1975-12-01 |
| CS183675B2 (en) | 1978-07-31 |
| GB1373324A (en) | 1974-11-13 |
| RO62861A (fr) | 1977-11-15 |
| AR193463A1 (es) | 1973-04-23 |
| GT198062785A (es) | 1981-09-19 |
| SU447888A3 (ru) | 1974-10-25 |
| ZA73702B (en) | 1973-10-31 |
| NO136096B (ro) | 1977-04-12 |
| AU464773B2 (en) | 1975-09-04 |
| PL79604B1 (ro) | 1975-06-30 |
| ES411154A1 (es) | 1976-03-16 |
| IE37169L (en) | 1973-08-01 |
| LU66931A1 (ro) | 1973-04-02 |
| DE2204574A1 (de) | 1973-08-09 |
| DK132408C (da) | 1976-05-03 |
| NL7301245A (ro) | 1973-08-03 |
| CH576458A5 (ro) | 1976-06-15 |
| DD103897A5 (ro) | 1974-02-12 |
| AU5162073A (en) | 1974-08-01 |
| BE794742A (fr) | 1973-07-30 |
| US3868371A (en) | 1975-02-25 |
| JPS4882017A (ro) | 1973-11-02 |
| SE393612B (sv) | 1977-05-16 |
| IL41426A0 (en) | 1973-03-30 |
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