CA947277A - 6.alpha.-FLUORO-16.alpha.,18-DIMETHYL-.DELTA.1,4-PREGNADIENE-3-20-DIONES - Google Patents

6.alpha.-FLUORO-16.alpha.,18-DIMETHYL-.DELTA.1,4-PREGNADIENE-3-20-DIONES

Info

Publication number
CA947277A
CA947277A CA131423A CA131423A CA947277A CA 947277 A CA947277 A CA 947277A CA 131423 A CA131423 A CA 131423A CA 131423 A CA131423 A CA 131423A CA 947277 A CA947277 A CA 947277A
Authority
CA
Canada
Prior art keywords
alpha
pregnadiene
diones
fluoro
delta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA131423A
Other languages
English (en)
Other versions
CA131423S (en
Inventor
Karl Petzoldt
Rudolf Wiechert
Ulrich Kerb
Klaus Kieslich
Karl H. Kolb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA947277A publication Critical patent/CA947277A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
CA131423A 1970-12-30 1971-12-30 6.alpha.-FLUORO-16.alpha.,18-DIMETHYL-.DELTA.1,4-PREGNADIENE-3-20-DIONES Expired CA947277A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2064859A DE2064859C3 (de) 1970-12-30 1970-12-30 Neue 6 a -Fluor-16 a , 18dimethyl-l,4-pregnadien-3,20-dion Derivate, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CA947277A true CA947277A (en) 1974-05-14

Family

ID=5792810

Family Applications (1)

Application Number Title Priority Date Filing Date
CA131423A Expired CA947277A (en) 1970-12-30 1971-12-30 6.alpha.-FLUORO-16.alpha.,18-DIMETHYL-.DELTA.1,4-PREGNADIENE-3-20-DIONES

Country Status (20)

Country Link
US (1) US3787454A (de)
AT (1) AT312823B (de)
AU (1) AU464245B2 (de)
BE (1) BE777549A (de)
CA (1) CA947277A (de)
CH (1) CH571539A5 (de)
CS (1) CS166792B2 (de)
DE (1) DE2064859C3 (de)
DK (1) DK127420B (de)
EG (1) EG10342A (de)
FI (1) FI49160C (de)
FR (1) FR2120112B1 (de)
GB (1) GB1378168A (de)
HU (1) HU163052B (de)
IE (1) IE35896B1 (de)
IL (1) IL38473A (de)
NL (1) NL7118166A (de)
SE (1) SE377804B (de)
SU (2) SU468409A3 (de)
ZA (1) ZA717774B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1036870B (it) * 1975-02-13 1979-10-30 Acraf Derivati steroidei dell acido bendazolico
CH633562A5 (de) * 1976-12-10 1982-12-15 Schering Ag Verfahren zur herstellung neuer kortikoide.
US4740372A (en) * 1986-09-17 1988-04-26 Ljubomir Boncic Composition for treating psoriasis vulgaris and a method for its preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1643036B2 (de) * 1967-08-16 1976-04-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue 11 beta-halogensteroide, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung
US3529000A (en) * 1968-01-29 1970-09-15 American Home Prod C-21 hydroxylation products of steroids

Also Published As

Publication number Publication date
BE777549A (fr) 1972-06-30
IE35896L (en) 1972-06-30
SE377804B (de) 1975-07-28
SU504493A4 (ru) 1976-02-25
FR2120112B1 (de) 1975-04-18
DE2064859B2 (de) 1979-09-13
HU163052B (de) 1973-05-28
FI49160C (fi) 1975-04-10
CS166792B2 (de) 1976-03-29
NL7118166A (de) 1972-07-04
ZA717774B (en) 1972-08-30
CH571539A5 (de) 1976-01-15
AT312823B (de) 1974-01-25
GB1378168A (en) 1974-12-27
IL38473A (en) 1975-08-31
DE2064859A1 (de) 1972-07-20
US3787454A (en) 1974-01-22
DE2064859C3 (de) 1980-05-22
FR2120112A1 (de) 1972-08-11
IL38473A0 (en) 1972-02-29
IE35896B1 (en) 1976-06-23
AU464245B2 (en) 1975-08-04
FI49160B (de) 1974-12-31
SU468409A3 (ru) 1975-04-25
DK127420B (da) 1973-11-05
AU3608271A (en) 1973-05-31
PL74486B1 (de) 1974-10-30
EG10342A (en) 1976-05-31

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