CA943966A - Acyl xylidide local anaesthetics - Google Patents

Acyl xylidide local anaesthetics

Info

Publication number
CA943966A
CA943966A CA130,662A CA130662A CA943966A CA 943966 A CA943966 A CA 943966A CA 130662 A CA130662 A CA 130662A CA 943966 A CA943966 A CA 943966A
Authority
CA
Canada
Prior art keywords
xylidide
acyl
local anaesthetics
anaesthetics
local
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA130,662A
Other languages
English (en)
Inventor
Bertil H. Takman
Herbert J.F. Adams
George H. Kronberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ASTRA PHARMACEUTICAL PRODUCTS
Original Assignee
ASTRA PHARMACEUTICAL PRODUCTS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ASTRA PHARMACEUTICAL PRODUCTS filed Critical ASTRA PHARMACEUTICAL PRODUCTS
Application granted granted Critical
Publication of CA943966A publication Critical patent/CA943966A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/38—Acyl halides
    • C07C53/46—Acyl halides containing halogen outside the carbonyl halide group
    • C07C53/50—Acyl halides containing halogen outside the carbonyl halide group of acids containing three or more carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
CA130,662A 1970-12-22 1971-12-21 Acyl xylidide local anaesthetics Expired CA943966A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10077770A 1970-12-22 1970-12-22
US00164022A US3812147A (en) 1970-12-22 1971-07-19 Acylxylidide local anaesthetics

Publications (1)

Publication Number Publication Date
CA943966A true CA943966A (en) 1974-03-19

Family

ID=26797539

Family Applications (1)

Application Number Title Priority Date Filing Date
CA130,662A Expired CA943966A (en) 1970-12-22 1971-12-21 Acyl xylidide local anaesthetics

Country Status (23)

Country Link
US (1) US3812147A (pl)
JP (1) JPS5644063B1 (pl)
AR (1) AR193840A1 (pl)
AT (1) AT319205B (pl)
AU (1) AU468489B2 (pl)
BE (1) BE776656A (pl)
BR (1) BR7108466D0 (pl)
CA (1) CA943966A (pl)
DD (1) DD99779A5 (pl)
DE (1) DE2162744C3 (pl)
DK (1) DK139814B (pl)
ES (2) ES398210A1 (pl)
FI (1) FI55027C (pl)
FR (1) FR2118985B1 (pl)
GB (1) GB1369259A (pl)
HU (1) HU163373B (pl)
IE (1) IE35909B1 (pl)
IT (1) IT1066334B (pl)
NL (2) NL172149C (pl)
NO (1) NO135934C (pl)
PL (1) PL83097B1 (pl)
SE (1) SE393374B (pl)
SU (1) SU419023A3 (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237068A (en) * 1971-07-28 1980-12-02 Astra Pharmaceutical Products, Inc. Primary aminoacylanilides
US3966934A (en) * 1971-12-08 1976-06-29 Astra Pharmaceutical Products, Inc. Synergistic local anesthetic compositions
US3957996A (en) * 1971-12-08 1976-05-18 Astra Pharmaceutical Products, Inc. Pharmaceutical local anesthetic compositions
US3975443A (en) * 1972-06-06 1976-08-17 Allen & Hanburys Limited 1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine
JPS598269B2 (ja) * 1975-08-22 1984-02-23 萬有製薬株式会社 オメガ − アミノアルカンサンアリ−ルアミドノ セイホウ
EP0062322A1 (en) * 1981-04-03 1982-10-13 The B.F. GOODRICH Company Improved process for synthesis of hindered amine stabilizers for polymeric materials
US4891058A (en) * 1988-07-18 1990-01-02 Ici Americas Inc. 1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use
SE8900685D0 (sv) * 1989-02-28 1989-02-28 Astra Ab New compounds
US5153226A (en) * 1989-08-31 1992-10-06 Warner-Lambert Company Acat inhibitors for treating hypocholesterolemia
JP2010510227A (ja) 2006-11-20 2010-04-02 プレジデント アンド フェロウズ オブ ハーバード カレッジ 痛みおよび痒みの治療方法、組成物およびキット
US20120172429A1 (en) 2009-07-10 2012-07-05 Woolf Clifford J Permanently charged sodium and calcium channel blockers as anti- inflammatory agents
RU2018107695A (ru) 2015-08-03 2019-09-05 Президент Энд Феллоуз Оф Гарвард Колледж Заряженные блокаторы ионных каналов и способы их применения
AU2020237474A1 (en) 2019-03-11 2021-09-30 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
SG11202109720WA (en) 2019-03-11 2021-10-28 Nocion Therapeutics Inc Charged ion channel blockers and methods for use
KR20210145164A (ko) 2019-03-11 2021-12-01 녹시온 테라퓨틱스 인코포레이티드 에스테르 치환된 이온 채널 차단제 및 사용 방법
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
WO2021091586A1 (en) 2019-11-06 2021-05-14 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10842798B1 (en) 2019-11-06 2020-11-24 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
AU2021236130A1 (en) 2020-03-11 2022-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1124837A (en) * 1966-06-03 1968-08-21 Wyeth John & Brother Ltd Substituted anilides

Also Published As

Publication number Publication date
GB1369259A (en) 1974-10-23
BR7108466D0 (pt) 1973-06-14
IE35909L (en) 1972-06-22
PL83097B1 (pl) 1975-12-31
DE2162744A1 (de) 1972-07-06
FR2118985A1 (pl) 1972-08-04
SE393374B (sv) 1977-05-09
AU468489B2 (en) 1976-01-15
AT319205B (de) 1974-12-10
BE776656A (fr) 1972-06-14
AR193840A1 (es) 1973-05-31
ES398210A1 (es) 1975-03-16
NL8204126A (nl) 1983-02-01
FI55027B (fi) 1979-01-31
IT1066334B (it) 1985-03-04
DE2162744B2 (de) 1981-07-02
JPS5644063B1 (pl) 1981-10-16
NL172149C (nl) 1983-07-18
NL172149B (nl) 1983-02-16
IE35909B1 (en) 1976-06-23
DD99779A5 (pl) 1973-08-20
HU163373B (pl) 1973-08-28
DK139814B (da) 1979-04-23
NL7117644A (pl) 1972-06-26
US3812147A (en) 1974-05-21
FI55027C (fi) 1979-05-10
AU3709971A (en) 1973-06-28
DK139814C (pl) 1979-10-01
FR2118985B1 (pl) 1975-12-26
NO135934C (pl) 1977-06-29
DE2162744C3 (de) 1982-04-15
SU419023A3 (ru) 1974-03-05
ES425626A1 (es) 1976-06-16
NO135934B (pl) 1977-03-21

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