CA3224701A1 - Process for making diaryl isoxazoline derivative - Google Patents

Process for making diaryl isoxazoline derivative Download PDF

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Publication number
CA3224701A1
CA3224701A1 CA3224701A CA3224701A CA3224701A1 CA 3224701 A1 CA3224701 A1 CA 3224701A1 CA 3224701 A CA3224701 A CA 3224701A CA 3224701 A CA3224701 A CA 3224701A CA 3224701 A1 CA3224701 A1 CA 3224701A1
Authority
CA
Canada
Prior art keywords
formula
compound
alkyl
clause
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3224701A
Other languages
English (en)
French (fr)
Inventor
Jingdan Hu
Guanmin Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elanco US Inc
Original Assignee
Elanco US Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elanco US Inc filed Critical Elanco US Inc
Publication of CA3224701A1 publication Critical patent/CA3224701A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3224701A 2021-08-11 2022-08-10 Process for making diaryl isoxazoline derivative Pending CA3224701A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163231858P 2021-08-11 2021-08-11
US63/231,858 2021-08-11
US202263306240P 2022-02-03 2022-02-03
US63/306,240 2022-02-03
PCT/US2022/039965 WO2023018806A1 (en) 2021-08-11 2022-08-10 Process for making diaryl isoxazoline derivative

Publications (1)

Publication Number Publication Date
CA3224701A1 true CA3224701A1 (en) 2023-02-16

Family

ID=83191860

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3224701A Pending CA3224701A1 (en) 2021-08-11 2022-08-10 Process for making diaryl isoxazoline derivative

Country Status (10)

Country Link
US (1) US20240308993A1 (enExample)
EP (1) EP4384514A1 (enExample)
JP (1) JP2024531064A (enExample)
KR (1) KR20240046112A (enExample)
AU (1) AU2022326468A1 (enExample)
BR (1) BR112023026362A2 (enExample)
CA (1) CA3224701A1 (enExample)
MX (1) MX2023014962A (enExample)
TW (1) TW202312880A (enExample)
WO (1) WO2023018806A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12655138B2 (en) 2020-07-24 2026-06-16 Elanco Us Inc. Process for making an isoxazoline compound and intermediate thereof
NO20240925A1 (en) 2023-09-15 2025-03-17 Evah Atlantic Inc Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish
CN117486869A (zh) * 2023-11-06 2024-02-02 北京康立生医药技术开发有限公司 一种眼科治疗药物新的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5365807B2 (ja) * 2007-11-12 2013-12-11 日産化学工業株式会社 光学活性イソキサゾリン化合物の触媒的不斉合成方法
AR074790A1 (es) 2008-12-19 2011-02-09 Novartis Ag Derivados de isooxazol sustituidos, composiciones farmaceuticas y para el control de parasitos que los comprenden y su uso en metodos para controlar parasitos en y sobre animales de sangre caliente.
US20140206633A1 (en) 2010-02-25 2014-07-24 Syngenta Crop Protection Llc Process for the preparation of isoxazoline derivatives
CA2826067A1 (en) * 2011-02-10 2012-08-16 Novartis Ag Isoxazoline derivatives for controlling invertebrate pests
JP6075563B2 (ja) 2011-11-08 2017-02-08 日産化学工業株式会社 光学活性イソキサゾリン化合物の触媒的不斉合成方法及び光学活性イソキサゾリン化合物
US20140343085A1 (en) 2011-11-29 2014-11-20 Novartis Ag Use of aryl derivatives for controlling ectoparasites
CN104169276A (zh) 2012-02-03 2014-11-26 佐蒂斯有限责任公司 作为抗寄生物剂的手性异噁唑啉氮杂环丁烷衍生物的制备方法
EP2922854B1 (en) 2012-11-21 2022-05-04 Zoetis Services LLC Synthesis of spirocyclic isoxazoline derivatives
WO2014090918A1 (en) 2012-12-13 2014-06-19 Novartis Ag Process for the enantiomeric enrichment of diaryloxazoline derivatives
EP3018129A1 (en) * 2014-11-10 2016-05-11 Novartis Tiergesundheit AG Diaryl isoxazoline compound
MY189534A (en) 2016-04-06 2022-02-16 Merial Inc Process for the preparation of isoxazoline compounds
CN119033777A (zh) * 2016-05-10 2024-11-29 瑞士伊兰科动物保健有限公司 用于控制海虱的二氢异噁唑化合物

Also Published As

Publication number Publication date
TW202312880A (zh) 2023-04-01
JP2024531064A (ja) 2024-08-29
MX2023014962A (es) 2024-02-13
BR112023026362A2 (pt) 2024-03-05
KR20240046112A (ko) 2024-04-08
EP4384514A1 (en) 2024-06-19
WO2023018806A1 (en) 2023-02-16
AU2022326468A1 (en) 2023-11-30
US20240308993A1 (en) 2024-09-19

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