CA3212615A1 - Chimeric antigen receptors targeting claudin-3 and methods for treating cancer - Google Patents

Chimeric antigen receptors targeting claudin-3 and methods for treating cancer Download PDF

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Publication number
CA3212615A1
CA3212615A1 CA3212615A CA3212615A CA3212615A1 CA 3212615 A1 CA3212615 A1 CA 3212615A1 CA 3212615 A CA3212615 A CA 3212615A CA 3212615 A CA3212615 A CA 3212615A CA 3212615 A1 CA3212615 A1 CA 3212615A1
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cell
cells
seq
claudin
cancer
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English (en)
French (fr)
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Thomas SOUTHGATE
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GlaxoSmithKline Intellectual Property Development Ltd
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GlaxoSmithKline Intellectual Property Development Ltd
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    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/00Cellular immunotherapy
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    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31Chimeric antigen receptors [CAR]
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    • A61K40/4214Receptors for cytokines
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    • A61K2239/50Colon
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CA3212615A 2021-03-19 2022-03-17 Chimeric antigen receptors targeting claudin-3 and methods for treating cancer Pending CA3212615A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163163217P 2021-03-19 2021-03-19
US63/163,217 2021-03-19
PCT/IB2022/052443 WO2022195535A1 (en) 2021-03-19 2022-03-17 Chimeric antigen receptors targeting claudin-3 and methods for treating cancer

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Publication Number Publication Date
CA3212615A1 true CA3212615A1 (en) 2022-09-22

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CA3212615A Pending CA3212615A1 (en) 2021-03-19 2022-03-17 Chimeric antigen receptors targeting claudin-3 and methods for treating cancer

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US (1) US20230192842A1 (https=)
EP (1) EP4308605A1 (https=)
JP (1) JP2024513713A (https=)
KR (1) KR20230160307A (https=)
CN (2) CN118638226A (https=)
AR (1) AR125136A1 (https=)
BR (1) BR112023018987A2 (https=)
CA (1) CA3212615A1 (https=)
TW (1) TW202304960A (https=)
WO (1) WO2022195535A1 (https=)

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Publication number Priority date Publication date Assignee Title
KR20240176948A (ko) * 2023-06-15 2024-12-26 에이비온 주식회사 소세포폐암 진단 및 치료를 위한 타겟으로서 클라우딘-3의 용도

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Publication number Priority date Publication date Assignee Title
JPS57106673A (en) 1980-12-24 1982-07-02 Chugai Pharmaceut Co Ltd Dibenzo(b,f)(1,4)oxazepin derivative
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5283173A (en) 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
US5994136A (en) 1997-12-12 1999-11-30 Cell Genesys, Inc. Method and means for producing high titer, safe, recombinant lentivirus vectors
US20050089932A1 (en) 2001-04-26 2005-04-28 Avidia Research Institute Novel proteins with targeted binding
US20050053973A1 (en) 2001-04-26 2005-03-10 Avidia Research Institute Novel proteins with targeted binding
WO2002088346A2 (en) 2001-05-01 2002-11-07 National Research Council Of Canada A system for inducible expression in eukaryotic cells
US20050164301A1 (en) 2003-10-24 2005-07-28 Avidia Research Institute LDL receptor class A and EGF domain monomers and multimers
CA2672581A1 (en) * 2006-12-14 2008-06-19 Forerunner Pharma Research Co., Ltd. Anti-claudin 3 monoclonal antibody and treatment and diagnosis of cancer using the same
JP7098521B2 (ja) 2015-11-24 2022-07-11 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド レトロウイルス産生のための安定な細胞株
EP3380605A1 (en) 2015-11-24 2018-10-03 GlaxoSmithKline Intellectual Property Development Limited Transient transfection method for retroviral production
KR102340989B1 (ko) * 2018-03-28 2021-12-20 에이비온 주식회사 클라우딘 3의 ecl-2에 특이적으로 결합하는 항체, 이의 단편 및 이들의 용도
KR20210037581A (ko) * 2019-09-26 2021-04-06 (재)록원바이오융합연구재단 항-클라우딘-3 키메라 항원 수용체

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WO2022195535A1 (en) 2022-09-22
JP2024513713A (ja) 2024-03-27
AR125136A1 (es) 2023-06-14
US20230192842A1 (en) 2023-06-22
KR20230160307A (ko) 2023-11-23
CN117377691A (zh) 2024-01-09
EP4308605A1 (en) 2024-01-24
CN118638226A (zh) 2024-09-13
TW202304960A (zh) 2023-02-01
BR112023018987A2 (pt) 2023-12-05

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