CA3166852A1 - Engineered polypeptides derived from variable domain of adenovirus penton base - Google Patents
Engineered polypeptides derived from variable domain of adenovirus penton base Download PDFInfo
- Publication number
- CA3166852A1 CA3166852A1 CA3166852A CA3166852A CA3166852A1 CA 3166852 A1 CA3166852 A1 CA 3166852A1 CA 3166852 A CA3166852 A CA 3166852A CA 3166852 A CA3166852 A CA 3166852A CA 3166852 A1 CA3166852 A1 CA 3166852A1
- Authority
- CA
- Canada
- Prior art keywords
- amino acid
- fragment
- polypeptide
- sequence
- terminal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10323—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10333—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20155742.8 | 2020-02-05 | ||
| EP20155742 | 2020-02-05 | ||
| EP20155982.0 | 2020-02-06 | ||
| EP20155982 | 2020-02-06 | ||
| PCT/EP2021/052884 WO2021156489A1 (en) | 2020-02-05 | 2021-02-05 | Engineered polypeptides derived from variable domain of adenovirus penton base |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3166852A1 true CA3166852A1 (en) | 2021-08-12 |
Family
ID=74561908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3166852A Pending CA3166852A1 (en) | 2020-02-05 | 2021-02-05 | Engineered polypeptides derived from variable domain of adenovirus penton base |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230101439A1 (enExample) |
| EP (1) | EP4100421A1 (enExample) |
| JP (1) | JP2023513512A (enExample) |
| CN (1) | CN115427431A (enExample) |
| AU (1) | AU2021216124A1 (enExample) |
| BR (1) | BR112022015461A2 (enExample) |
| CA (1) | CA3166852A1 (enExample) |
| MX (1) | MX2022009574A (enExample) |
| WO (1) | WO2021156489A1 (enExample) |
| ZA (1) | ZA202209759B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024042100A1 (en) | 2022-08-22 | 2024-02-29 | Imophoron Limited | Adenovirus penton-based virus-like particles |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080004228A1 (en) | 2004-03-09 | 2008-01-03 | Imre Berger | New Expression Tools for Multiprotein Applications |
| HUE039908T2 (hu) * | 2009-02-02 | 2019-02-28 | Glaxosmithkline Biologicals Sa | Majom adenovírusból származó nukleinsav- és aminosav-szekvenciák, azt tartalmazó vektorok és alkalmazásuk |
| WO2010100278A2 (en) | 2009-03-06 | 2010-09-10 | Europäisches Laboratorium für Molekularbiologie (EMBL) | Nucleic acids for cloning and expressing multiprotein complexes |
| PL222497B1 (pl) * | 2009-06-26 | 2016-08-31 | Inst Biochemii I Biofizyki Pan | Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania, kompozycja farmaceutyczna oraz zastosowanie wektorowej cząsteczki wirusopodobnej |
| RS64059B1 (sr) * | 2016-03-31 | 2023-04-28 | The European Molecular Biology Laboratory | Protein adenoviralnog omotača izveden iz vehikuluma za isporuku |
| GB201620968D0 (en) * | 2016-12-09 | 2017-01-25 | Glaxosmithkline Biologicals Sa | Adenovirus polynucleotides and polypeptides |
| EP3655539A1 (en) * | 2017-07-21 | 2020-05-27 | GlaxoSmithKline Biologicals S.A. | Chikungunya virus antigen constructs |
| EP3830250A1 (en) * | 2018-07-31 | 2021-06-09 | Imophoron Limited | Multimerizing polypeptides derived from jelly roll fold domain of adenovirus penton base |
-
2021
- 2021-02-05 WO PCT/EP2021/052884 patent/WO2021156489A1/en not_active Ceased
- 2021-02-05 AU AU2021216124A patent/AU2021216124A1/en not_active Abandoned
- 2021-02-05 MX MX2022009574A patent/MX2022009574A/es unknown
- 2021-02-05 BR BR112022015461A patent/BR112022015461A2/pt not_active IP Right Cessation
- 2021-02-05 CN CN202180024156.1A patent/CN115427431A/zh active Pending
- 2021-02-05 EP EP21703917.1A patent/EP4100421A1/en not_active Withdrawn
- 2021-02-05 US US17/797,941 patent/US20230101439A1/en not_active Abandoned
- 2021-02-05 CA CA3166852A patent/CA3166852A1/en active Pending
- 2021-02-05 JP JP2022547688A patent/JP2023513512A/ja active Pending
-
2022
- 2022-08-31 ZA ZA2022/09759A patent/ZA202209759B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021216124A1 (en) | 2022-09-29 |
| MX2022009574A (es) | 2022-11-16 |
| JP2023513512A (ja) | 2023-03-31 |
| WO2021156489A1 (en) | 2021-08-12 |
| CN115427431A (zh) | 2022-12-02 |
| ZA202209759B (en) | 2023-07-26 |
| BR112022015461A2 (pt) | 2022-10-11 |
| EP4100421A1 (en) | 2022-12-14 |
| US20230101439A1 (en) | 2023-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20220803 |
|
| P13 | Application amended |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-P146 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: BSL VERIFIED - NO DEFECTS Effective date: 20240830 |
|
| W00 | Other event occurred |
Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT Effective date: 20250826 |
|
| U13 | Renewal or maintenance fee not paid |
Free format text: ST27 STATUS EVENT CODE: N-2-6-U10-U13-U300 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: DEEMED ABANDONED - FAILURE TO RESPOND TO MAINTENANCE FEE NOTICE Effective date: 20251027 |
|
| W00 | Other event occurred |
Free format text: ST27 STATUS EVENT CODE: N-6-6-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT Effective date: 20260102 |
|
| W00 | Other event occurred |
Free format text: ST27 STATUS EVENT CODE: N-6-6-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT Effective date: 20260319 |