CA3163319A1 - Pan-cancer platinum response predictor - Google Patents
Pan-cancer platinum response predictorInfo
- Publication number
- CA3163319A1 CA3163319A1 CA3163319A CA3163319A CA3163319A1 CA 3163319 A1 CA3163319 A1 CA 3163319A1 CA 3163319 A CA3163319 A CA 3163319A CA 3163319 A CA3163319 A CA 3163319A CA 3163319 A1 CA3163319 A1 CA 3163319A1
- Authority
- CA
- Canada
- Prior art keywords
- cancer
- data
- machine learning
- treatment
- biomarkers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N20/00—Machine learning
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N3/00—Computing arrangements based on biological models
- G06N3/02—Neural networks
- G06N3/08—Learning methods
- G06N3/084—Backpropagation, e.g. using gradient descent
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/40—Population genetics; Linkage disequilibrium
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Data Mining & Analysis (AREA)
- Primary Health Care (AREA)
- Epidemiology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Databases & Information Systems (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Software Systems (AREA)
- Biotechnology (AREA)
- Computing Systems (AREA)
- Artificial Intelligence (AREA)
- Evolutionary Computation (AREA)
- General Physics & Mathematics (AREA)
- Mathematical Physics (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Ecology (AREA)
- Physiology (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2019/064078 WO2020113237A1 (en) | 2018-11-30 | 2019-12-02 | Next-generation molecular profiling |
| USPCT/US2019/064078 | 2019-12-02 | ||
| US202062965601P | 2020-01-24 | 2020-01-24 | |
| US62/965,601 | 2020-01-24 | ||
| US202063005105P | 2020-04-03 | 2020-04-03 | |
| US63/005,105 | 2020-04-03 | ||
| US202063012740P | 2020-04-20 | 2020-04-20 | |
| US63/012,740 | 2020-04-20 | ||
| PCT/US2020/035990 WO2021112918A1 (en) | 2019-12-02 | 2020-06-03 | Pan-cancer platinum response predictor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3163319A1 true CA3163319A1 (en) | 2021-06-10 |
Family
ID=76222159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3163319A Pending CA3163319A1 (en) | 2019-12-02 | 2020-06-03 | Pan-cancer platinum response predictor |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11842805B2 (https=) |
| EP (1) | EP4069865A4 (https=) |
| JP (2) | JP7624992B2 (https=) |
| KR (2) | KR20260043144A (https=) |
| AU (1) | AU2020397802A1 (https=) |
| CA (1) | CA3163319A1 (https=) |
| IL (1) | IL293489A (https=) |
| MX (1) | MX2022006589A (https=) |
| WO (1) | WO2021112918A1 (https=) |
Families Citing this family (33)
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| GB2536650A (en) | 2015-03-24 | 2016-09-28 | Augmedics Ltd | Method and system for combining video-based and optic-based augmented reality in a near eye display |
| US12521201B2 (en) | 2017-12-07 | 2026-01-13 | Augmedics Ltd. | Spinous process clamp |
| US12458411B2 (en) | 2017-12-07 | 2025-11-04 | Augmedics Ltd. | Spinous process clamp |
| US11980507B2 (en) | 2018-05-02 | 2024-05-14 | Augmedics Ltd. | Registration of a fiducial marker for an augmented reality system |
| US11766296B2 (en) | 2018-11-26 | 2023-09-26 | Augmedics Ltd. | Tracking system for image-guided surgery |
| US11922314B1 (en) * | 2018-11-30 | 2024-03-05 | Ansys, Inc. | Systems and methods for building dynamic reduced order physical models |
| JP7462632B2 (ja) | 2018-11-30 | 2024-04-05 | カリス エムピーアイ インコーポレイテッド | 次世代分子プロファイリング |
| US11980506B2 (en) | 2019-07-29 | 2024-05-14 | Augmedics Ltd. | Fiducial marker |
| US12178666B2 (en) | 2019-07-29 | 2024-12-31 | Augmedics Ltd. | Fiducial marker |
| US11382712B2 (en) | 2019-12-22 | 2022-07-12 | Augmedics Ltd. | Mirroring in image guided surgery |
| CN115917668A (zh) * | 2020-06-12 | 2023-04-04 | 霍夫曼-拉罗奇有限公司 | 用于促进个体多发性硬化症受试者的协同治疗的大数据处理 |
| US11389252B2 (en) | 2020-06-15 | 2022-07-19 | Augmedics Ltd. | Rotating marker for image guided surgery |
| US12239385B2 (en) | 2020-09-09 | 2025-03-04 | Augmedics Ltd. | Universal tool adapter |
| US12502163B2 (en) | 2020-09-09 | 2025-12-23 | Augmedics Ltd. | Universal tool adapter for image-guided surgery |
| US12271832B2 (en) * | 2021-02-12 | 2025-04-08 | Tempus Ai, Inc. | Artificial intelligence engine for directed hypothesis generation and ranking |
| JP2022124165A (ja) * | 2021-02-15 | 2022-08-25 | キオクシア株式会社 | メモリシステム |
| US11896445B2 (en) | 2021-07-07 | 2024-02-13 | Augmedics Ltd. | Iliac pin and adapter |
| US12150821B2 (en) | 2021-07-29 | 2024-11-26 | Augmedics Ltd. | Rotating marker and adapter for image-guided surgery |
| CA3227993A1 (en) * | 2021-08-11 | 2023-02-16 | OncoHost Ltd. | Predicting patient response |
| EP4387552A4 (en) | 2021-08-18 | 2025-04-30 | Augmedics Ltd. | AUGMENTED REALITY SURGICAL SYSTEM USING DEPTH SENSING |
| US20240387047A1 (en) * | 2021-09-15 | 2024-11-21 | Oxford Cancer Analytics (Oxcan) | A method and system detecting a health abnormality in a liquid biopsy sample |
| CA3233981A1 (en) * | 2021-10-13 | 2023-04-20 | John Michael NICOLUDIS | High-throughput prediction of variant effects from conformational dynamics |
| WO2023085932A1 (en) * | 2021-11-10 | 2023-05-19 | Omnigen B.V. | Prediction of response following folfirinox treatment in cancer patients |
| EP4511809A4 (en) | 2022-04-21 | 2026-03-11 | Augmedics Ltd | Systems and methods for medical image visualization |
| EP4587881A1 (en) | 2022-09-13 | 2025-07-23 | Augmedics Ltd. | Augmented reality eyewear for image-guided medical intervention |
| CN115631849B (zh) * | 2022-10-19 | 2023-04-28 | 哈尔滨工业大学 | 基于深度神经网络的乳腺癌预后指示系统、存储介质及设备 |
| US12266005B2 (en) * | 2022-11-30 | 2025-04-01 | Maplebear Inc. | Identifying candidate replacement items with a source similarity score |
| JP2025049280A (ja) * | 2023-09-21 | 2025-04-03 | ソフトバンクグループ株式会社 | システム |
| JP2025056785A (ja) * | 2023-09-26 | 2025-04-08 | ソフトバンクグループ株式会社 | システム |
| JP2025157946A (ja) * | 2024-04-03 | 2025-10-16 | 株式会社日立製作所 | 治療効果予測システムおよび方法 |
| WO2025255578A1 (en) | 2024-06-07 | 2025-12-11 | Caris Mpi, Inc. | Dual-modality models for digital pathology |
| US20260023671A1 (en) * | 2024-07-17 | 2026-01-22 | International Business Machines Corporation | Log anomaly detection based on golden signal templates |
| US12586686B1 (en) * | 2025-02-11 | 2026-03-24 | PointHealth AI, INC. | Treatment recommendations using genomic data and reinforcement learning |
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