CA3159845A1 - Device, system and methods for the oral delivery of therapeutic compounds - Google Patents
Device, system and methods for the oral delivery of therapeutic compounds Download PDFInfo
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- CA3159845A1 CA3159845A1 CA3159845A CA3159845A CA3159845A1 CA 3159845 A1 CA3159845 A1 CA 3159845A1 CA 3159845 A CA3159845 A CA 3159845A CA 3159845 A CA3159845 A CA 3159845A CA 3159845 A1 CA3159845 A1 CA 3159845A1
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- OGBMKVWORPGQRR-UMXFMPSGSA-N teriparatide Chemical compound C([C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CNC=N1 OGBMKVWORPGQRR-UMXFMPSGSA-N 0.000 description 1
- 229960005460 teriparatide Drugs 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
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- 229940088594 vitamin Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/073—Intestinal transmitters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Surgery (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Anesthesiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Optics & Photonics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161571641P | 2011-06-29 | 2011-06-29 | |
| US61/571,641 | 2011-06-29 | ||
| CA2840487A CA2840487C (en) | 2011-06-29 | 2012-06-27 | Device, system and methods for the oral delivery of therapeutic compounds |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2840487A Division CA2840487C (en) | 2011-06-29 | 2012-06-27 | Device, system and methods for the oral delivery of therapeutic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3159845A1 true CA3159845A1 (en) | 2013-01-03 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3159845A Pending CA3159845A1 (en) | 2011-06-29 | 2012-06-27 | Device, system and methods for the oral delivery of therapeutic compounds |
| CA2840487A Active CA2840487C (en) | 2011-06-29 | 2012-06-27 | Device, system and methods for the oral delivery of therapeutic compounds |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2840487A Active CA2840487C (en) | 2011-06-29 | 2012-06-27 | Device, system and methods for the oral delivery of therapeutic compounds |
Country Status (11)
| Country | Link |
|---|---|
| EP (3) | EP3973983A1 (enExample) |
| JP (6) | JP6101261B2 (enExample) |
| CN (1) | CN103987422B (enExample) |
| AU (5) | AU2012275417B9 (enExample) |
| CA (2) | CA3159845A1 (enExample) |
| DK (2) | DK2726141T3 (enExample) |
| ES (2) | ES2898893T3 (enExample) |
| IN (1) | IN2014CN00338A (enExample) |
| PL (2) | PL2726141T3 (enExample) |
| PT (2) | PT2726141T (enExample) |
| WO (1) | WO2013003487A1 (enExample) |
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| EP3466438A1 (en) | 2009-08-03 | 2019-04-10 | Incube Labs, Llc | Swallowable capsule and method for stimulating incretin production within the intestinal tract |
| US8562589B2 (en) | 2009-12-24 | 2013-10-22 | Rani Therapeutics, Llc | Swallowable drug delivery device and method of delivery |
| US8846040B2 (en) | 2010-12-23 | 2014-09-30 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8969293B2 (en) | 2010-12-23 | 2015-03-03 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8980822B2 (en) | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8764733B2 (en) | 2010-12-23 | 2014-07-01 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US9284367B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8809271B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising liraglutide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9149617B2 (en) | 2010-12-23 | 2015-10-06 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US9861683B2 (en) | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9629799B2 (en) | 2010-12-23 | 2017-04-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9283179B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10639272B2 (en) | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402807B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| ES2898893T3 (es) * | 2011-06-29 | 2022-03-09 | Rani Therapeutics Llc | Dispositivo para la administración por vía oral de compuestos terapéuticos |
| CA3240667A1 (en) * | 2013-03-15 | 2014-10-02 | Rani Therapeutics, Llc | Device for oral delivery of therapeutic compounds |
| CN104605900B (zh) * | 2013-11-04 | 2017-04-12 | 上海交通大学医学院附属第九人民医院 | 一种可同时提供生物附加效应的皮肤扩张器 |
| CN113368233A (zh) | 2014-05-15 | 2021-09-10 | 拉尼医疗有限公司 | 包含多肽和/或蛋白质的固体块的药物组合物和该固体块的制备方法 |
| US11548940B2 (en) | 2014-05-15 | 2023-01-10 | Rani Therapeutics, Llc | Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10227403B2 (en) | 2014-05-15 | 2019-03-12 | Incube Labs, Llc | Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins |
| US10689460B2 (en) | 2014-05-15 | 2020-06-23 | Incube Labs, Llc | PCSK9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| CN104287685B (zh) * | 2014-10-08 | 2016-03-02 | 南京航空航天大学 | 弹性杆导向式胶囊内镜机器人驻停及位姿调整装置与方法 |
| AU2016261599B2 (en) * | 2015-05-08 | 2021-08-26 | Rani Therapeutics, Llc | Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| DK3347050T3 (da) * | 2015-09-08 | 2025-04-14 | Rani Therapeutics Llc | PCSK9-antistofpræparater til afgivelse i et lumen i mave-tarmkanalen ved hjælp af en indtagelig enhed til afgivelse af lægemiddel |
| US10190894B2 (en) * | 2015-12-26 | 2019-01-29 | Intel Corporation | Technologies for controlling degradation of sensing circuits |
| CN105476593B (zh) * | 2015-12-30 | 2019-02-05 | 中科院合肥技术创新工程院 | 一种用于检查食管疾病的胶囊内窥镜 |
| US10220003B2 (en) * | 2016-03-09 | 2019-03-05 | Incube Labs, Llc | Methods and articles for delivering viable cells into solid tissue |
| JP7295811B2 (ja) * | 2017-05-17 | 2023-06-21 | マサチューセッツ インスティテュート オブ テクノロジー | 自己作動物品 |
| JP7423530B2 (ja) * | 2017-12-18 | 2024-01-29 | バイオグライル アンパーツゼルスカブ | 活性薬剤物質の経口送達 |
| US20200323426A1 (en) * | 2018-01-03 | 2020-10-15 | Mi Fitpill Medical Ltd. | In-vivo insertable devices having fail-safe evacuation |
| US10675248B2 (en) | 2018-08-14 | 2020-06-09 | Alma Therapeutics Ltd. | Expandable pill |
| KR102047610B1 (ko) * | 2018-12-18 | 2019-11-22 | 이민우 | 다수의 소형 주사기 또는 주사부를 갖는 마이크로 니들 장치 |
| IL285899B2 (en) | 2019-03-14 | 2025-01-01 | Esocap Ag | Pharmaceutical dosage form for application to mucous membranes and methods for its production |
| CA3156044A1 (en) * | 2019-10-01 | 2021-04-08 | Rani Therapeutics, Llc | Self-sizing device for delivering a formulation to a lumen wall |
| CN115300774B (zh) * | 2022-08-27 | 2024-01-30 | 深圳市资福医疗技术有限公司 | 一种药剂递送装置、释药方法及应用其的释药胶囊 |
| US20250120580A1 (en) * | 2023-10-12 | 2025-04-17 | Boston Scientific Scimed, Inc. | Devices, systems, and related methods for delivering agents to body lumens |
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| JPS60129057A (ja) * | 1983-12-14 | 1985-07-10 | 住友化学工業株式会社 | 針状固形製剤投与針 |
| DK42093D0 (da) * | 1993-04-07 | 1993-04-07 | Bukh Meditec | Administrationsmetode |
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| US7946979B2 (en) | 2002-12-26 | 2011-05-24 | Given Imaging, Ltd. | Immobilizable in vivo sensing device |
| US20050058701A1 (en) * | 2003-01-29 | 2005-03-17 | Yossi Gross | Active drug delivery in the gastrointestinal tract |
| JP2006517827A (ja) * | 2003-01-29 | 2006-08-03 | イー−ピル・ファーマ・リミテッド | 胃腸管内における活性薬物の送達 |
| US20050038415A1 (en) * | 2003-08-06 | 2005-02-17 | Rohr William L. | Method and apparatus for the treatment of obesity |
| JP4526253B2 (ja) * | 2003-10-01 | 2010-08-18 | オリンパス株式会社 | 体内観察装置 |
| DE102004026615A1 (de) * | 2004-06-01 | 2005-12-29 | Siemens Ag | Vorrichtung und Verfahren zur Freisetzung eines in das Körperinnere eines Patienten geführten therapeutischen Mittels |
| EP1827388A2 (en) * | 2004-12-14 | 2007-09-05 | E-Pill Pharma Ltd. | Local delivery of drugs or substances using electronic permeability increase |
| CN101107038A (zh) * | 2005-01-18 | 2008-01-16 | 皇家飞利浦电子股份有限公司 | 电控胶囊 |
| US7785291B2 (en) | 2005-03-01 | 2010-08-31 | Tulip Medical Ltd. | Bioerodible self-deployable intragastric implants |
| DE102005032369A1 (de) | 2005-07-08 | 2007-01-11 | Siemens Ag | Endoskopiekapsel |
| JP4402648B2 (ja) | 2005-12-16 | 2010-01-20 | オリンパス株式会社 | 被検体内導入装置 |
| JP5220001B2 (ja) * | 2006-05-18 | 2013-06-26 | チューリップ メディカル リミテッド | 生体内分解性の自己展開式の胃内インプラントおよび胃以外のインプラント |
| US20070288033A1 (en) * | 2006-06-09 | 2007-12-13 | Allergan, Inc. | Intragastric balloon retrieval mechanisms |
| US8162969B2 (en) * | 2008-10-16 | 2012-04-24 | Obalon Therapeutics, Inc. | Intragastric device |
| WO2010093834A2 (en) * | 2009-02-12 | 2010-08-19 | Incube Labs, Llc | Skin penetrating device and method for subcutaneous solid drug delivery |
| JP2010273936A (ja) * | 2009-05-29 | 2010-12-09 | Tti Ellebeau Inc | バルーンカテーテル |
| CA2785168C (en) | 2009-12-24 | 2018-04-17 | Incube Labs, Llc | Swallowable drug delivery device and methods of drug delivery |
| US8562589B2 (en) * | 2009-12-24 | 2013-10-22 | Rani Therapeutics, Llc | Swallowable drug delivery device and method of delivery |
| ES2898893T3 (es) * | 2011-06-29 | 2022-03-09 | Rani Therapeutics Llc | Dispositivo para la administración por vía oral de compuestos terapéuticos |
-
2012
- 2012-06-27 ES ES19203957T patent/ES2898893T3/es active Active
- 2012-06-27 WO PCT/US2012/044441 patent/WO2013003487A1/en not_active Ceased
- 2012-06-27 JP JP2014518971A patent/JP6101261B2/ja active Active
- 2012-06-27 CA CA3159845A patent/CA3159845A1/en active Pending
- 2012-06-27 EP EP21192893.2A patent/EP3973983A1/en active Pending
- 2012-06-27 PL PL12804668T patent/PL2726141T3/pl unknown
- 2012-06-27 CA CA2840487A patent/CA2840487C/en active Active
- 2012-06-27 IN IN338CHN2014 patent/IN2014CN00338A/en unknown
- 2012-06-27 PT PT128046687T patent/PT2726141T/pt unknown
- 2012-06-27 ES ES12804668T patent/ES2765029T3/es active Active
- 2012-06-27 PL PL19203957T patent/PL3653223T3/pl unknown
- 2012-06-27 DK DK12804668.7T patent/DK2726141T3/da active
- 2012-06-27 CN CN201280041936.8A patent/CN103987422B/zh active Active
- 2012-06-27 DK DK19203957.6T patent/DK3653223T3/da active
- 2012-06-27 EP EP19203957.6A patent/EP3653223B1/en active Active
- 2012-06-27 AU AU2012275417A patent/AU2012275417B9/en active Active
- 2012-06-27 EP EP12804668.7A patent/EP2726141B1/en active Active
- 2012-06-27 PT PT192039576T patent/PT3653223T/pt unknown
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2017
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2018
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2020
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2022
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2024
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