IN2014CN00338A - - Google Patents
Info
- Publication number
- IN2014CN00338A IN2014CN00338A IN338CHN2014A IN2014CN00338A IN 2014CN00338 A IN2014CN00338 A IN 2014CN00338A IN 338CHN2014 A IN338CHN2014 A IN 338CHN2014A IN 2014CN00338 A IN2014CN00338 A IN 2014CN00338A
- Authority
- IN
- India
- Prior art keywords
- capsule
- intestinal wall
- lumen
- tract
- drugs
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/073—Intestinal transmitters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Embodiments of the invention provide swallowable devices preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule advanced from the capsule into the intestinal wall and degrade within the wall to release the drug to produce a therapeutic effect. The preparation can be coupled to a delivery mechanism having one or more balloons or other expandable devices which are expandable responsive to a condition in the small intestine or other GI lumen to advance the preparation out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed tolerated and/or degraded within the GI tract.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161571641P | 2011-06-29 | 2011-06-29 | |
PCT/US2012/044441 WO2013003487A1 (en) | 2011-06-29 | 2012-06-27 | Device, system and methods for the oral delivery of therapeutic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014CN00338A true IN2014CN00338A (en) | 2015-04-03 |
Family
ID=47424526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN338CHN2014 IN2014CN00338A (en) | 2011-06-29 | 2012-06-27 |
Country Status (11)
Country | Link |
---|---|
EP (3) | EP3653223B1 (en) |
JP (6) | JP6101261B2 (en) |
CN (1) | CN103987422B (en) |
AU (5) | AU2012275417B9 (en) |
CA (2) | CA3159845A1 (en) |
DK (2) | DK2726141T3 (en) |
ES (2) | ES2898893T3 (en) |
IN (1) | IN2014CN00338A (en) |
PL (2) | PL2726141T3 (en) |
PT (2) | PT2726141T (en) |
WO (1) | WO2013003487A1 (en) |
Families Citing this family (39)
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CN102770151B (en) | 2009-08-03 | 2018-07-31 | 因卡伯实验室有限责任公司 | For stimulating what incretin in enteron aisle generated to swallow formula capsule and method |
US8721620B2 (en) | 2009-12-24 | 2014-05-13 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
US8764733B2 (en) | 2010-12-23 | 2014-07-01 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9284367B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9861683B2 (en) | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8846040B2 (en) | 2010-12-23 | 2014-09-30 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8969293B2 (en) | 2010-12-23 | 2015-03-03 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US10639272B2 (en) | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
US9629799B2 (en) | 2010-12-23 | 2017-04-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9149617B2 (en) | 2010-12-23 | 2015-10-06 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8980822B2 (en) | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9283179B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9402807B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8809271B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising liraglutide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
JP6101261B2 (en) * | 2011-06-29 | 2017-03-22 | ラニ セラピューティクス, エルエルシー | Devices, systems, and methods for oral delivery of therapeutic compounds |
CA3104670A1 (en) * | 2013-03-15 | 2014-10-02 | Rani Therapeutics, Llc | Device for oral delivery of therapeutic compounds |
CN104605900B (en) * | 2013-11-04 | 2017-04-12 | 上海交通大学医学院附属第九人民医院 | Skin expander capable of simultaneously providing biological additive effect |
US10689460B2 (en) | 2014-05-15 | 2020-06-23 | Incube Labs, Llc | PCSK9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US11548940B2 (en) | 2014-05-15 | 2023-01-10 | Rani Therapeutics, Llc | Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
CN104287685B (en) * | 2014-10-08 | 2016-03-02 | 南京航空航天大学 | Parked and the pose adjusting device of elastic rod guide type capsule endoscope robot and method |
EP3288543A4 (en) | 2015-05-01 | 2018-11-14 | Incube Labs, LLC | Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins |
WO2016183040A1 (en) * | 2015-05-08 | 2016-11-17 | Mir Imran | Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
AU2016320867B2 (en) * | 2015-09-08 | 2023-03-30 | Rani Therapeutics, Llc | PCSK9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US10190894B2 (en) * | 2015-12-26 | 2019-01-29 | Intel Corporation | Technologies for controlling degradation of sensing circuits |
CN105476593B (en) * | 2015-12-30 | 2019-02-05 | 中科院合肥技术创新工程院 | It is a kind of for checking the capsule endoscope of esophagel disease |
US10220003B2 (en) * | 2016-03-09 | 2019-03-05 | Incube Labs, Llc | Methods and articles for delivering viable cells into solid tissue |
WO2018213588A1 (en) * | 2017-05-17 | 2018-11-22 | Massachusetts Institute Of Technology | Tissue anchoring articles |
WO2019121686A1 (en) * | 2017-12-18 | 2019-06-27 | Egalet Ltd. | Oral delivery of active drug substances |
CN111526789A (en) * | 2018-01-03 | 2020-08-11 | Mi菲特皮尔医疗有限责任公司 | Body-insertable apparatus with fail-safe expulsion |
US10675248B2 (en) | 2018-08-14 | 2020-06-09 | Alma Therapeutics Ltd. | Expandable pill |
KR102047610B1 (en) * | 2018-12-18 | 2019-11-22 | 이민우 | Micro Needle Device with Multi Mini-Injection Part |
US20220151939A1 (en) * | 2019-03-14 | 2022-05-19 | Esocap Ag | Pharmaceutical dosage form for application to mucous membranes and methods for producing same |
CN114650864A (en) * | 2019-10-01 | 2022-06-21 | 拉尼医疗有限公司 | Self-sizing device for delivery of formulations to lumen walls |
CN115300774B (en) * | 2022-08-27 | 2024-01-30 | 深圳市资福医疗技术有限公司 | Medicament delivery device, medicament release method and medicament release capsule using same |
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JPS60129057A (en) * | 1983-12-14 | 1985-07-10 | 住友化学工業株式会社 | Needle like solid drug administering needle |
DK42093D0 (en) * | 1993-04-07 | 1993-04-07 | Bukh Meditec | METHOD OF ADMINISTRATION |
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JP2006512130A (en) * | 2002-12-26 | 2006-04-13 | ギブン・イメージング・リミテツド | Immobilizable in vivo sensing device |
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KR20050098277A (en) * | 2003-01-29 | 2005-10-11 | 이-필 파마 리미티드 | Active drug delivery in the gastrointestinal tract |
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DE102004026615A1 (en) * | 2004-06-01 | 2005-12-29 | Siemens Ag | Apparatus and method for releasing a therapeutic agent delivered to the interior of a patient's body |
EP1827387A2 (en) * | 2004-12-14 | 2007-09-05 | E-Pill Pharma Ltd. | Prolonged transit time of permeability-enhancing drug eluting pill |
CN101107038A (en) | 2005-01-18 | 2008-01-16 | 皇家飞利浦电子股份有限公司 | Electronically controlled capsule |
US7785291B2 (en) * | 2005-03-01 | 2010-08-31 | Tulip Medical Ltd. | Bioerodible self-deployable intragastric implants |
DE102005032369A1 (en) | 2005-07-08 | 2007-01-11 | Siemens Ag | endoscopy capsule |
JP4402648B2 (en) * | 2005-12-16 | 2010-01-20 | オリンパス株式会社 | Intra-subject introduction device |
JP5220001B2 (en) * | 2006-05-18 | 2013-06-26 | チューリップ メディカル リミテッド | Biodegradable self-expanding intragastric and non-gastric implants |
US20070288033A1 (en) * | 2006-06-09 | 2007-12-13 | Allergan, Inc. | Intragastric balloon retrieval mechanisms |
WO2010045477A2 (en) * | 2008-10-16 | 2010-04-22 | Obalon Therapeutics, Inc. | Intragastric volume-occupying device and method for fabricating same |
WO2010093834A2 (en) * | 2009-02-12 | 2010-08-19 | Incube Labs, Llc | Skin penetrating device and method for subcutaneous solid drug delivery |
JP2010273936A (en) * | 2009-05-29 | 2010-12-09 | Tti Ellebeau Inc | Balloon catheter |
US8721620B2 (en) * | 2009-12-24 | 2014-05-13 | Rani Therapeutics, Llc | Swallowable drug delivery device and methods of drug delivery |
PL3461478T3 (en) | 2009-12-24 | 2020-09-21 | Rani Therapeutics, Llc | Swallowable drug delivery device |
JP6101261B2 (en) * | 2011-06-29 | 2017-03-22 | ラニ セラピューティクス, エルエルシー | Devices, systems, and methods for oral delivery of therapeutic compounds |
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2012
- 2012-06-27 JP JP2014518971A patent/JP6101261B2/en active Active
- 2012-06-27 ES ES19203957T patent/ES2898893T3/en active Active
- 2012-06-27 CA CA3159845A patent/CA3159845A1/en active Pending
- 2012-06-27 DK DK12804668.7T patent/DK2726141T3/en active
- 2012-06-27 DK DK19203957.6T patent/DK3653223T3/en active
- 2012-06-27 PT PT128046687T patent/PT2726141T/en unknown
- 2012-06-27 AU AU2012275417A patent/AU2012275417B9/en active Active
- 2012-06-27 CA CA2840487A patent/CA2840487C/en active Active
- 2012-06-27 PL PL12804668T patent/PL2726141T3/en unknown
- 2012-06-27 ES ES12804668T patent/ES2765029T3/en active Active
- 2012-06-27 CN CN201280041936.8A patent/CN103987422B/en active Active
- 2012-06-27 EP EP19203957.6A patent/EP3653223B1/en active Active
- 2012-06-27 PT PT192039576T patent/PT3653223T/en unknown
- 2012-06-27 EP EP12804668.7A patent/EP2726141B1/en active Active
- 2012-06-27 WO PCT/US2012/044441 patent/WO2013003487A1/en active Application Filing
- 2012-06-27 IN IN338CHN2014 patent/IN2014CN00338A/en unknown
- 2012-06-27 EP EP21192893.2A patent/EP3973983A1/en active Pending
- 2012-06-27 PL PL19203957T patent/PL3653223T3/en unknown
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2017
- 2017-02-24 JP JP2017033704A patent/JP2017113601A/en not_active Withdrawn
- 2017-07-20 AU AU2017206226A patent/AU2017206226B2/en active Active
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2018
- 2018-10-24 JP JP2018199734A patent/JP6742383B2/en active Active
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2020
- 2020-01-21 AU AU2020200413A patent/AU2020200413B2/en active Active
- 2020-07-28 JP JP2020127039A patent/JP7016387B2/en active Active
- 2020-12-31 AU AU2020294353A patent/AU2020294353B2/en active Active
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2022
- 2022-01-25 JP JP2022009746A patent/JP2022044726A/en active Pending
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2023
- 2023-04-06 AU AU2023202150A patent/AU2023202150A1/en active Pending
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2024
- 2024-04-04 JP JP2024060590A patent/JP2024074923A/en active Pending
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