CA3158513A1 - Methods for treating alzheimer's disease - Google Patents
Methods for treating alzheimer's diseaseInfo
- Publication number
- CA3158513A1 CA3158513A1 CA3158513A CA3158513A CA3158513A1 CA 3158513 A1 CA3158513 A1 CA 3158513A1 CA 3158513 A CA3158513 A CA 3158513A CA 3158513 A CA3158513 A CA 3158513A CA 3158513 A1 CA3158513 A1 CA 3158513A1
- Authority
- CA
- Canada
- Prior art keywords
- antibody
- subject
- tau
- amount
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962924633P | 2019-10-22 | 2019-10-22 | |
| US62/924,633 | 2019-10-22 | ||
| PCT/US2020/056676 WO2021081101A1 (en) | 2019-10-22 | 2020-10-21 | Anti-beta-amyloid antibody for treating alzheimer's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3158513A1 true CA3158513A1 (en) | 2021-04-29 |
Family
ID=73344157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3158513A Pending CA3158513A1 (en) | 2019-10-22 | 2020-10-21 | Methods for treating alzheimer's disease |
Country Status (13)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| EP3746476A1 (en) | 2018-01-31 | 2020-12-09 | Alector LLC | Anti-ms4a4a antibodies and methods of use thereof |
| EP3746484A4 (en) | 2018-01-31 | 2021-11-17 | Alector LLC | ANTI-MS4A6A ANTIBODY AND METHOD OF USING THEREOF |
| KR20210124308A (ko) | 2019-01-30 | 2021-10-14 | 트루바인딩 아이엔씨. | 항-gal3 항체 및 이의 용도 |
| MX2022014786A (es) | 2020-05-26 | 2023-01-16 | Truebinding Inc | Metodos para tratar enfermedades inflamatorias mediante el bloqueo de galectina-3. |
| TW202300517A (zh) * | 2021-03-12 | 2023-01-01 | 美商美國禮來大藥廠 | 抗類澱粉β抗體及其用途 |
| TW202300518A (zh) * | 2021-03-12 | 2023-01-01 | 美商美國禮來大藥廠 | 抗N3pGlu類澱粉β抗體及其用途 |
| WO2023081194A2 (en) * | 2021-11-03 | 2023-05-11 | Biogen Ma Inc. | Methods for treating alzheimer's disease |
| KR20240142535A (ko) * | 2022-02-02 | 2024-09-30 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | P-tau181 수준을 사용한 치료 방법 |
| WO2024086796A1 (en) * | 2022-10-20 | 2024-04-25 | Alector Llc | Anti-ms4a4a antibodies with amyloid-beta therapies |
| EP4608432A4 (en) * | 2022-10-25 | 2026-08-12 | Inst For Basic Science Ibs | EXTRACTION METHODS TO ENABLE CEREBRAL-SPINAL FLUID DRAINAGE |
| EP4455161A1 (en) | 2023-04-24 | 2024-10-30 | ONO Pharmaceutical Co., Ltd. | Human-derived anti-collapsin response mediator protein 2 (crmp2) antibodies |
| WO2025059487A2 (en) | 2023-09-15 | 2025-03-20 | Othair Prothena Limited | Cell penetrating agents and uses thereof |
| WO2025117721A1 (en) * | 2023-11-27 | 2025-06-05 | Massachusetts Institute Of Technology | Reconstituted lipoprotein particles to rescue lipid defects in the alzheimer's brain |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE033325T2 (en) | 2007-01-05 | 2017-11-28 | Univ Zuerich | Anti-beta-amyloid binder antibodies and their use |
| US9040045B2 (en) * | 2007-05-14 | 2015-05-26 | Medtronic, Inc. | Methods and device to neutralize soluble toxic agents in the brain |
| JO3076B1 (ar) * | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| US9221900B2 (en) * | 2010-07-30 | 2015-12-29 | Ac Immune S.A. | Methods for identifying safe and functional humanized antibodies |
| EP3275461A1 (en) * | 2011-09-19 | 2018-01-31 | Axon Neuroscience SE | Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease field |
| EP2928494A4 (en) * | 2012-12-07 | 2016-11-02 | Biogen Internat Neuroscience Gmbh | METHOD FOR REDUCING AMYLOIDER PLAQUE OF BRAIN WITH ANTI-ASS ANTIBODIES |
| MA41115A (fr) * | 2014-12-02 | 2017-10-10 | Biogen Int Neuroscience Gmbh | Procédé de traitement de la maladie d'alzheimer |
| MX2018015022A (es) * | 2016-06-07 | 2019-08-14 | Biogen Int Neuroscience Gmbh | Métodos para el tratamiento de la enfermedad de alzheimer. |
-
2020
- 2020-10-21 CN CN202080073830.0A patent/CN114599393A/zh active Pending
- 2020-10-21 US US17/770,997 patent/US20220372123A1/en active Pending
- 2020-10-21 IL IL292363A patent/IL292363A/en unknown
- 2020-10-21 CA CA3158513A patent/CA3158513A1/en active Pending
- 2020-10-21 MX MX2022004678A patent/MX2022004678A/es unknown
- 2020-10-21 BR BR112022007595A patent/BR112022007595A2/pt unknown
- 2020-10-21 JP JP2022523595A patent/JP2022553329A/ja active Pending
- 2020-10-21 KR KR1020227015913A patent/KR20220084095A/ko active Pending
- 2020-10-21 EP EP20804740.7A patent/EP4048695A1/en active Pending
- 2020-10-21 WO PCT/US2020/056676 patent/WO2021081101A1/en not_active Ceased
- 2020-10-21 AU AU2020371612A patent/AU2020371612A1/en active Pending
-
2022
- 2022-04-19 CO CONC2022/0004902A patent/CO2022004902A2/es unknown
- 2022-04-20 JO JOP/2022/0092A patent/JOP20220092A1/ar unknown
-
2025
- 2025-10-27 JP JP2025181171A patent/JP2026012271A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CO2022004902A2 (es) | 2022-07-08 |
| JP2022553329A (ja) | 2022-12-22 |
| EP4048695A1 (en) | 2022-08-31 |
| CN114599393A (zh) | 2022-06-07 |
| BR112022007595A2 (pt) | 2022-08-23 |
| US20220372123A1 (en) | 2022-11-24 |
| AU2020371612A1 (en) | 2022-05-19 |
| IL292363A (en) | 2022-06-01 |
| JOP20220092A1 (ar) | 2023-01-30 |
| KR20220084095A (ko) | 2022-06-21 |
| MX2022004678A (es) | 2022-08-15 |
| WO2021081101A1 (en) | 2021-04-29 |
| JP2026012271A (ja) | 2026-01-23 |
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