CA3146423A1 - Posologie amelioree du baloxavir marboxil pour patients pediatriques - Google Patents
Posologie amelioree du baloxavir marboxil pour patients pediatriques Download PDFInfo
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- CA3146423A1 CA3146423A1 CA3146423A CA3146423A CA3146423A1 CA 3146423 A1 CA3146423 A1 CA 3146423A1 CA 3146423 A CA3146423 A CA 3146423A CA 3146423 A CA3146423 A CA 3146423A CA 3146423 A1 CA3146423 A1 CA 3146423A1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention concerne un procédé de traitement d'une infection par le virus de la grippe, ledit procédé comprenant l'administration d'une quantité efficace d'un composé à un patient présentant une infection par le virus de la grippe, le composé ayant l'une des formules (I) et (II) ou étant un sel pharmaceutiquement acceptable de celles-ci, et la posologie suivante étant utilisée : (i) chez un patient qui est âgé de moins de 1 an : (a) si le patient est âgé de moins de 4 semaines, alors la quantité efficace est de 0,8 à 1,2 mg/kg de poids corporel, de préférence environ 1 mg/kg de poids corporel ; (b) si le patient est âgé de 4 semaines ou plus mais de moins de 3 mois, alors la quantité efficace est de 0,8 à 1,2 mg/kg de poids corporel, de préférence d'environ 1 mg/kg de poids corporel ; (c) si le patient est âgé de 3 mois ou plus mais de moins de 12 mois, alors la quantité efficace est de 1,8 à 2,2 mg/kg de poids corporel, de préférence d'environ 2 mg/kg de poids corporel ; (ii) chez un patient qui est âgé de 1 an ou plus mais de moins de 12 ans : (a) si le patient a un poids corporel inférieur à 20 kg, alors la quantité efficace est de 1,8 à 2,2 mg/kg de poids corporel, de préférence environ 2 mg/kg de poids corporel ; ou (b) si le patient a un poids corporel de 20 kg ou plus, alors la quantité efficace est de 35 à 45 mg, de préférence environ 40 mg.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2019/071699 WO2021028024A1 (fr) | 2019-08-13 | 2019-08-13 | Posologie améliorée du baloxavir marboxil pour patients pédiatriques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3146423A1 true CA3146423A1 (fr) | 2021-02-18 |
Family
ID=67734629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3146423A Pending CA3146423A1 (fr) | 2019-08-13 | 2019-08-13 | Posologie amelioree du baloxavir marboxil pour patients pediatriques |
Country Status (4)
| Country | Link |
|---|---|
| KR (1) | KR20220045199A (fr) |
| AU (1) | AU2019461218A1 (fr) |
| CA (1) | CA3146423A1 (fr) |
| WO (1) | WO2021028024A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3714889A1 (fr) | 2019-03-29 | 2020-09-30 | F. Hoffmann-La Roche AG | Composé et procédé pour la prévention de la transmission du virus de la grippe |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4219508B1 (fr) | 2015-04-28 | 2024-06-05 | Shionogi & Co., Ltd | Dérivé de pyridone polycyclique substitué et promédicament de celui-ci |
| CN110494141A (zh) * | 2016-08-10 | 2019-11-22 | 盐野义制药株式会社 | 含有被取代的多环性吡啶酮衍生物及其前药的药物组合物 |
-
2019
- 2019-08-13 AU AU2019461218A patent/AU2019461218A1/en active Pending
- 2019-08-13 KR KR1020227007735A patent/KR20220045199A/ko unknown
- 2019-08-13 WO PCT/EP2019/071699 patent/WO2021028024A1/fr active Application Filing
- 2019-08-13 CA CA3146423A patent/CA3146423A1/fr active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019461218A1 (en) | 2022-02-03 |
| WO2021028024A1 (fr) | 2021-02-18 |
| KR20220045199A (ko) | 2022-04-12 |
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