CA3128232A1 - Enhanced nitrate compositions and methods of use - Google Patents

Enhanced nitrate compositions and methods of use Download PDF

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Publication number
CA3128232A1
CA3128232A1 CA3128232A CA3128232A CA3128232A1 CA 3128232 A1 CA3128232 A1 CA 3128232A1 CA 3128232 A CA3128232 A CA 3128232A CA 3128232 A CA3128232 A CA 3128232A CA 3128232 A1 CA3128232 A1 CA 3128232A1
Authority
CA
Canada
Prior art keywords
elemental
nitrate anion
composition
nitrate
source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3128232A
Other languages
English (en)
French (fr)
Inventor
Alexandros Nikolaidis
Ronald Kramer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermolife International LLC
Original Assignee
Thermolife International LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thermolife International LLC filed Critical Thermolife International LLC
Publication of CA3128232A1 publication Critical patent/CA3128232A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
CA3128232A 2019-02-01 2020-01-31 Enhanced nitrate compositions and methods of use Pending CA3128232A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962800361P 2019-02-01 2019-02-01
US62/800,361 2019-02-01
US201962866540P 2019-06-25 2019-06-25
US62/866,540 2019-06-25
US16/779,349 2020-01-31
US16/779,349 US20200222449A1 (en) 2019-02-01 2020-01-31 Enhanced Nitrate Compositions and Methods of Use
PCT/US2020/016274 WO2020160509A1 (en) 2019-02-01 2020-01-31 Enhanced nitrate compositions and methods of use

Publications (1)

Publication Number Publication Date
CA3128232A1 true CA3128232A1 (en) 2020-08-06

Family

ID=71517286

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3128232A Pending CA3128232A1 (en) 2019-02-01 2020-01-31 Enhanced nitrate compositions and methods of use

Country Status (12)

Country Link
US (5) US20200222449A1 (enExample)
EP (1) EP3917543B1 (enExample)
JP (1) JP7534310B2 (enExample)
KR (1) KR102789451B1 (enExample)
CN (1) CN113498345A (enExample)
AU (2) AU2020215729B2 (enExample)
BR (1) BR112021015110A2 (enExample)
CA (1) CA3128232A1 (enExample)
EA (1) EA202192132A1 (enExample)
IL (1) IL285247A (enExample)
MX (1) MX428917B (enExample)
WO (1) WO2020160509A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8466187B2 (en) 2007-09-18 2013-06-18 Thermolife International, Llc Amino acid compositions
US12612370B2 (en) 2011-03-02 2026-04-28 Thermolife International, Llc Amino acid compositions
US11865139B2 (en) 2020-11-12 2024-01-09 Thermolife International, Llc Method of treating migraines and headaches
JP2024541338A (ja) * 2020-11-12 2024-11-08 サーモライフ インターナショナル， エルエルシー 血中酸素飽和度を増大させる方法
EP4291206A4 (en) * 2021-02-11 2025-01-08 Thermolife International, LLC A method of administering nitric oxide gas
IL305762A (en) * 2021-03-11 2023-11-01 Thermolife Int Llc Compositions including nitrate, metal element and amino acid, and methods of use
US20230057399A1 (en) * 2021-08-16 2023-02-23 Thermolife International, Llc Iron supplement compositions and methods of use thereof
US20240226140A1 (en) * 2023-01-09 2024-07-11 Azulent, Llc Nitric oxide and molecular hydrogen generating compositions

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU476799B2 (en) * 1974-02-04 1976-08-05 Carlton And United Breweries Limited Preparation of a water soluble isomerised hop extract
US6703056B2 (en) * 2000-09-29 2004-03-09 The Procter + Gamble Co. Beverage compositions comprising arabinogalactan and defined minerals
US7208170B2 (en) * 2002-09-20 2007-04-24 Petersson Lennart G Powder teat dip germicide, fungicide and skin conditioner
AU2003289208A1 (en) * 2002-12-06 2004-06-30 Kyowa Hakko Kogyo Co., Ltd. Beverage containing amino acid and method of diminishing bitterness of amino acid
CA2678093C (en) * 2007-02-26 2017-10-24 Jon Lundberg Performance enhancing composition and use thereof
US7777074B2 (en) 2007-09-18 2010-08-17 Thermolife International, Llc Amino acid compounds
US10646508B1 (en) * 2007-09-18 2020-05-12 Thermolife International, Llc Method of safely administering nitrate dietary supplements and compositions
WO2009147229A1 (en) * 2008-06-06 2009-12-10 Phytolab Gmbh & Co. Kg Synergistic enhancement of cellular ergogenic nutrient uptake, like creatine or carnitine, with tarragon
US8303995B1 (en) * 2008-06-13 2012-11-06 Board Of Regents, The University Of Texas System Nitrite formulations and their use as nitric oxide prodrugs
ES2538652T3 (es) * 2009-06-16 2015-06-23 Dusan Miljkovic Composiciones y procedimientos para producir un potencial negativo de oxidación-reducción estable en materiales consumibles
JP2014513527A (ja) * 2011-04-21 2014-06-05 ネステク ソシエテ アノニム パフォーマンス向上のための栄養組成物並びにその作製及び使用方法
JP6016610B2 (ja) * 2012-12-20 2016-10-26 江崎グリコ株式会社 筋肉増量用サプリメント
AU2015334553B2 (en) * 2014-10-22 2020-03-05 Innoveco Australia Pty. Ltd. Process for metal extraction with sorption leaching in wet solids
ES2651717B1 (es) * 2016-07-26 2018-11-16 Lara OLLER DUQUE Solución acuosa cristaloide isotónica
US10624921B2 (en) * 2016-11-15 2020-04-21 Berkeley Nox Limited Dietary supplements
US11541020B2 (en) * 2019-04-16 2023-01-03 Thermolife International, Llc Hexylamine salts and methods of using hexylamine

Also Published As

Publication number Publication date
IL285247A (en) 2021-09-30
EP3917543A4 (en) 2022-10-12
JP7534310B2 (ja) 2024-08-14
KR20210119499A (ko) 2021-10-05
AU2023203649B2 (en) 2024-11-14
BR112021015110A2 (pt) 2022-01-11
EP3917543A1 (en) 2021-12-08
EA202192132A1 (ru) 2021-10-19
US20240122969A1 (en) 2024-04-18
JP2022523513A (ja) 2022-04-25
WO2020160509A1 (en) 2020-08-06
US20240122966A1 (en) 2024-04-18
US20240122968A1 (en) 2024-04-18
KR102789451B1 (ko) 2025-03-31
MX2021009287A (es) 2021-11-12
AU2023203649A1 (en) 2023-07-06
EP3917543B1 (en) 2026-07-01
US20240122967A1 (en) 2024-04-18
MX428917B (es) 2025-11-13
AU2020215729A1 (en) 2021-09-02
AU2020215729B2 (en) 2023-03-30
US20200222449A1 (en) 2020-07-16
CN113498345A (zh) 2021-10-12

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