CA3124806C - Chromatographic media for storage and delivery of therapeutic biologics and small molecules - Google Patents
Chromatographic media for storage and delivery of therapeutic biologics and small molecules Download PDFInfo
- Publication number
- CA3124806C CA3124806C CA3124806A CA3124806A CA3124806C CA 3124806 C CA3124806 C CA 3124806C CA 3124806 A CA3124806 A CA 3124806A CA 3124806 A CA3124806 A CA 3124806A CA 3124806 C CA3124806 C CA 3124806C
- Authority
- CA
- Canada
- Prior art keywords
- composite material
- certain embodiments
- dried
- stabilizing agent
- relates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261588312P | 2012-01-19 | 2012-01-19 | |
| US61/588,312 | 2012-01-19 | ||
| CA2861932A CA2861932C (en) | 2012-01-19 | 2013-01-18 | Chromatographic media for storage and delivery of therapeutic biologics and small molecules |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2861932A Division CA2861932C (en) | 2012-01-19 | 2013-01-18 | Chromatographic media for storage and delivery of therapeutic biologics and small molecules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA3124806A1 CA3124806A1 (en) | 2013-07-27 |
| CA3124806C true CA3124806C (en) | 2023-09-26 |
Family
ID=48797397
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3124806A Active CA3124806C (en) | 2012-01-19 | 2013-01-18 | Chromatographic media for storage and delivery of therapeutic biologics and small molecules |
| CA2861932A Active CA2861932C (en) | 2012-01-19 | 2013-01-18 | Chromatographic media for storage and delivery of therapeutic biologics and small molecules |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2861932A Active CA2861932C (en) | 2012-01-19 | 2013-01-18 | Chromatographic media for storage and delivery of therapeutic biologics and small molecules |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20130189322A1 (enExample) |
| EP (1) | EP2804634B1 (enExample) |
| JP (2) | JP6552822B2 (enExample) |
| KR (1) | KR102113296B1 (enExample) |
| AU (1) | AU2013209620B2 (enExample) |
| CA (2) | CA3124806C (enExample) |
| DK (1) | DK2804634T3 (enExample) |
| ES (1) | ES2750211T3 (enExample) |
| IN (1) | IN2014DN06817A (enExample) |
| WO (1) | WO2013109825A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY178616A (en) | 2012-09-17 | 2020-10-19 | Grace W R & Co | Chromatography media and devices |
| US9738683B2 (en) | 2013-07-25 | 2017-08-22 | Bio-Rad Laboratories, Inc. | Enhanced functionality and delivery of a protein from a porous substrate |
| FR3012978A1 (fr) * | 2013-11-12 | 2015-05-15 | Biocarecell | Filtre biocompatible et procede de fabrication d'un filtre biocompatible. |
| JP6853670B2 (ja) | 2014-01-16 | 2021-04-07 | ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ | 親和性クロマトグラフィー媒体及びクロマトグラフィーデバイス |
| JP6914189B2 (ja) | 2014-05-02 | 2021-08-04 | ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ | 官能化担体材料並びに官能化担体材料を作製及び使用する方法 |
| IS3008B (is) * | 2014-05-14 | 2018-12-15 | Calor ehf | Stöðgandi lausnir fyrir prótín og peptíð |
| CN107921407B (zh) | 2015-06-05 | 2022-07-05 | 格雷斯公司 | 生物处理吸附澄清剂及其制备和使用方法 |
| CA3097058A1 (en) * | 2018-04-16 | 2019-10-24 | Merck Patent Gmbh | Additives for protein formulations to improve thermal stability |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5059654A (en) * | 1983-02-14 | 1991-10-22 | Cuno Inc. | Affinity matrices of modified polysaccharide supports |
| JPH0779694B2 (ja) * | 1985-07-09 | 1995-08-30 | カドラント バイオリソ−シズ リミテツド | 蛋白質および同類品の保護 |
| CA2073511A1 (en) * | 1990-11-14 | 1992-05-29 | Matthew R. Callstrom | Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins |
| US5159049A (en) * | 1991-04-22 | 1992-10-27 | Allen Robert C | Method for stabilizing polyacrylamide gels |
| US5583162A (en) * | 1994-06-06 | 1996-12-10 | Biopore Corporation | Polymeric microbeads and method of preparation |
| US6284282B1 (en) * | 1998-04-29 | 2001-09-04 | Genentech, Inc. | Method of spray freeze drying proteins for pharmaceutical administration |
| SE9904475D0 (sv) * | 1999-12-08 | 1999-12-08 | Artursson | Nucleic acid delivery system |
| US6896894B2 (en) * | 2001-10-30 | 2005-05-24 | Battelle Memorial Institute | Proteins stabilized with polysaccharide gums |
| NZ535008A (en) * | 2002-02-08 | 2005-09-30 | Alkermes Inc | Polymer-based compositions for sustained release |
| US20040137004A1 (en) * | 2002-03-19 | 2004-07-15 | Glenn Gregory M | Patch for transcutaneous immunization |
| US6666281B2 (en) | 2002-03-19 | 2003-12-23 | Deere & Company | Bearing guard for a ground-working implement |
| EP2143482A1 (en) * | 2003-02-19 | 2010-01-13 | Natrix Separations Inc. | Composite materials comprising supported porous gels |
| US7785769B2 (en) * | 2003-07-25 | 2010-08-31 | The United States of America as reprsented by the Secretary of the Navy | Immobilization of oligonucleotides and proteins in sugar-containing hydrogels |
| EP1758671B9 (en) | 2004-04-08 | 2014-02-19 | Natrix Separations Inc. | Membrane stacks |
| EP2168975A3 (en) * | 2004-05-24 | 2012-01-11 | Genvault Corporation | Method of stably storing biomolecules in recoverable form |
| JP4806401B2 (ja) * | 2004-06-07 | 2011-11-02 | ナトリックス セパレイションズ インコーポレーテッド | 支持型多孔質ゲルを含む安定な複合材料 |
-
2013
- 2013-01-18 WO PCT/US2013/022057 patent/WO2013109825A1/en not_active Ceased
- 2013-01-18 CA CA3124806A patent/CA3124806C/en active Active
- 2013-01-18 JP JP2014553432A patent/JP6552822B2/ja active Active
- 2013-01-18 ES ES13739077T patent/ES2750211T3/es active Active
- 2013-01-18 EP EP13739077.9A patent/EP2804634B1/en active Active
- 2013-01-18 US US13/744,583 patent/US20130189322A1/en not_active Abandoned
- 2013-01-18 DK DK13739077T patent/DK2804634T3/da active
- 2013-01-18 AU AU2013209620A patent/AU2013209620B2/en active Active
- 2013-01-18 KR KR1020147022518A patent/KR102113296B1/ko active Active
- 2013-01-18 CA CA2861932A patent/CA2861932C/en active Active
- 2013-01-18 IN IN6817DEN2014 patent/IN2014DN06817A/en unknown
-
2018
- 2018-09-20 JP JP2018175774A patent/JP2019011341A/ja active Pending
-
2019
- 2019-09-04 US US16/560,370 patent/US20200069602A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014DN06817A (enExample) | 2015-05-22 |
| DK2804634T3 (da) | 2019-11-04 |
| JP2019011341A (ja) | 2019-01-24 |
| WO2013109825A1 (en) | 2013-07-25 |
| US20130189322A1 (en) | 2013-07-25 |
| AU2013209620B2 (en) | 2017-06-15 |
| JP2015504092A (ja) | 2015-02-05 |
| US20200069602A1 (en) | 2020-03-05 |
| EP2804634A1 (en) | 2014-11-26 |
| CA3124806A1 (en) | 2013-07-27 |
| KR20140117529A (ko) | 2014-10-07 |
| AU2013209620A1 (en) | 2014-08-28 |
| KR102113296B1 (ko) | 2020-06-02 |
| ES2750211T3 (es) | 2020-03-25 |
| EP2804634B1 (en) | 2019-08-28 |
| EP2804634A4 (en) | 2015-07-22 |
| JP6552822B2 (ja) | 2019-07-31 |
| CA2861932A1 (en) | 2013-07-27 |
| CA2861932C (en) | 2021-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20210909 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 12TH ANNIV.) - STANDARD Year of fee payment: 12 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20241207 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20241207 |
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| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 13TH ANNIV.) - STANDARD Year of fee payment: 13 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20251218 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20251218 |