JP6552822B2 - 治療用生物薬剤及び小分子の貯蔵及び送達のためのクロマトグラフィー媒体 - Google Patents

治療用生物薬剤及び小分子の貯蔵及び送達のためのクロマトグラフィー媒体 Download PDF

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JP6552822B2
JP6552822B2 JP2014553432A JP2014553432A JP6552822B2 JP 6552822 B2 JP6552822 B2 JP 6552822B2 JP 2014553432 A JP2014553432 A JP 2014553432A JP 2014553432 A JP2014553432 A JP 2014553432A JP 6552822 B2 JP6552822 B2 JP 6552822B2
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certain embodiments
composite material
relates
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composite materials
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JP2015504092A (ja
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チッコスキー，ジョン，エー．
ハニーマン，チャールズ，エイチ．
マクグラフリン，モリー，エス．
ラゲブ，アムロ
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ナトリックス セパレイションズ インコーポレーテッド
ナトリックス セパレイションズ インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2014553432A 2012-01-19 2013-01-18 治療用生物薬剤及び小分子の貯蔵及び送達のためのクロマトグラフィー媒体 Active JP6552822B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261588312P 2012-01-19 2012-01-19
US61/588,312 2012-01-19
PCT/US2013/022057 WO2013109825A1 (en) 2012-01-19 2013-01-18 Chromatographic media for storage and delivery of therapeutic biologics and small molecules

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018175774A Division JP2019011341A (ja) 2012-01-19 2018-09-20 治療用生物薬剤及び小分子の貯蔵及び送達のためのクロマトグラフィー媒体

Publications (2)

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JP2015504092A JP2015504092A (ja) 2015-02-05
JP6552822B2 true JP6552822B2 (ja) 2019-07-31

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JP2014553432A Active JP6552822B2 (ja) 2012-01-19 2013-01-18 治療用生物薬剤及び小分子の貯蔵及び送達のためのクロマトグラフィー媒体
JP2018175774A Pending JP2019011341A (ja) 2012-01-19 2018-09-20 治療用生物薬剤及び小分子の貯蔵及び送達のためのクロマトグラフィー媒体

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JP2018175774A Pending JP2019011341A (ja) 2012-01-19 2018-09-20 治療用生物薬剤及び小分子の貯蔵及び送達のためのクロマトグラフィー媒体

Country Status (10)

Country Link
US (2) US20130189322A1 (enExample)
EP (1) EP2804634B1 (enExample)
JP (2) JP6552822B2 (enExample)
KR (1) KR102113296B1 (enExample)
AU (1) AU2013209620B2 (enExample)
CA (2) CA2861932C (enExample)
DK (1) DK2804634T3 (enExample)
ES (1) ES2750211T3 (enExample)
IN (1) IN2014DN06817A (enExample)
WO (1) WO2013109825A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104968403A (zh) 2012-09-17 2015-10-07 格雷斯公司 色谱介质和装置
US9738683B2 (en) 2013-07-25 2017-08-22 Bio-Rad Laboratories, Inc. Enhanced functionality and delivery of a protein from a porous substrate
FR3012978A1 (fr) * 2013-11-12 2015-05-15 Biocarecell Filtre biocompatible et procede de fabrication d'un filtre biocompatible.
US11229896B2 (en) 2014-01-16 2022-01-25 W.R. Grace & Co.—Conn. Affinity chromatography media and chromatography devices
ES2929099T3 (es) 2014-05-02 2022-11-24 Grace W R & Co Material de soporte funcionalizado y métodos de fabricación y uso de material de soporte funcionalizado
IS3008B (is) * 2014-05-14 2018-12-15 Calor ehf Stöðgandi lausnir fyrir prótín og peptíð
PL3302784T3 (pl) 2015-06-05 2022-01-17 W.R. Grace & Co.-Conn. Adsorbentowe środki klarujące do bioprzetwarzania oraz sposoby ich wytwarzania i stosowania
CN112165951B (zh) * 2018-04-16 2024-12-13 默克专利股份有限公司 用于改善热稳定性的蛋白质制剂添加剂

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059654A (en) * 1983-02-14 1991-10-22 Cuno Inc. Affinity matrices of modified polysaccharide supports
US4891319A (en) * 1985-07-09 1990-01-02 Quadrant Bioresources Limited Protection of proteins and the like
WO1992008790A1 (en) * 1990-11-14 1992-05-29 Cargill, Incorporated Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
US5159049A (en) * 1991-04-22 1992-10-27 Allen Robert C Method for stabilizing polyacrylamide gels
US5583162A (en) * 1994-06-06 1996-12-10 Biopore Corporation Polymeric microbeads and method of preparation
US6284282B1 (en) * 1998-04-29 2001-09-04 Genentech, Inc. Method of spray freeze drying proteins for pharmaceutical administration
SE9904475D0 (sv) * 1999-12-08 1999-12-08 Artursson Nucleic acid delivery system
US6896894B2 (en) * 2001-10-30 2005-05-24 Battelle Memorial Institute Proteins stabilized with polysaccharide gums
AU2003217367B2 (en) * 2002-02-08 2005-09-08 Alkermes Controlled Therapeutics, Inc. Polymer-based compositions for sustained release
US6666281B2 (en) * 2002-03-19 2003-12-23 Deere & Company Bearing guard for a ground-working implement
US20040137004A1 (en) * 2002-03-19 2004-07-15 Glenn Gregory M Patch for transcutaneous immunization
AU2004212641B2 (en) 2003-02-19 2009-08-06 Merck Millipore Ltd. Composite materials comprising supported porous gels
US7785769B2 (en) * 2003-07-25 2010-08-31 The United States of America as reprsented by the Secretary of the Navy Immobilization of oligonucleotides and proteins in sugar-containing hydrogels
CA2558859C (en) 2004-04-08 2014-02-04 Mcmaster University Membrane stacks
CA2567720A1 (en) * 2004-05-24 2005-12-08 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form
EP1773485B1 (en) * 2004-06-07 2015-09-16 Natrix Separations Inc. Stable composite material comprising supported porous gels

Also Published As

Publication number Publication date
EP2804634B1 (en) 2019-08-28
JP2015504092A (ja) 2015-02-05
KR20140117529A (ko) 2014-10-07
CA2861932C (en) 2021-09-14
CA3124806C (en) 2023-09-26
CA2861932A1 (en) 2013-07-27
US20200069602A1 (en) 2020-03-05
JP2019011341A (ja) 2019-01-24
WO2013109825A1 (en) 2013-07-25
DK2804634T3 (da) 2019-11-04
EP2804634A1 (en) 2014-11-26
US20130189322A1 (en) 2013-07-25
IN2014DN06817A (enExample) 2015-05-22
ES2750211T3 (es) 2020-03-25
KR102113296B1 (ko) 2020-06-02
EP2804634A4 (en) 2015-07-22
AU2013209620B2 (en) 2017-06-15
CA3124806A1 (en) 2013-07-27
AU2013209620A1 (en) 2014-08-28

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