CA3119909A1 - A method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension - Google Patents
A method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension Download PDFInfo
- Publication number
- CA3119909A1 CA3119909A1 CA3119909A CA3119909A CA3119909A1 CA 3119909 A1 CA3119909 A1 CA 3119909A1 CA 3119909 A CA3119909 A CA 3119909A CA 3119909 A CA3119909 A CA 3119909A CA 3119909 A1 CA3119909 A1 CA 3119909A1
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- CA
- Canada
- Prior art keywords
- compound
- pharmaceutically acceptable
- diazaspiro
- pyrimidin
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862768575P | 2018-11-16 | 2018-11-16 | |
| US62/768,575 | 2018-11-16 | ||
| PCT/IB2019/001224 WO2020099926A1 (en) | 2018-11-16 | 2019-11-15 | A method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3119909A1 true CA3119909A1 (en) | 2020-05-22 |
Family
ID=69182543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3119909A Pending CA3119909A1 (en) | 2018-11-16 | 2019-11-15 | A method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11413287B2 (OSRAM) |
| EP (1) | EP3880203A1 (OSRAM) |
| JP (2) | JP2022507533A (OSRAM) |
| KR (1) | KR20210105343A (OSRAM) |
| CN (1) | CN113242736A (OSRAM) |
| AU (1) | AU2019382168A1 (OSRAM) |
| CA (1) | CA3119909A1 (OSRAM) |
| WO (1) | WO2020099926A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210105343A (ko) | 2018-11-16 | 2021-08-26 | 알타반트 사이언시스 게엠베하 | 폐동맥 고혈압 및 관련 폐동맥 고혈압의 치료 방법 |
| US20200188399A1 (en) * | 2018-12-17 | 2020-06-18 | Altavant Sciences Gmbh | Method for treating interstitial lung disease |
| WO2020157577A1 (en) * | 2019-01-30 | 2020-08-06 | Altavant Sciences Gmbh | A dosage regime and method for treating pulmonary arterial hypertension with rodatristat ethyl |
| JP2022525202A (ja) * | 2019-03-15 | 2022-05-11 | アルタバント・サイエンシズ・ゲーエムベーハー | 肺動脈性肺高血圧症および各種疾患に伴う肺動脈性肺高血圧症の治療法と１日あたりの投薬量 |
| WO2023062595A1 (en) | 2021-10-14 | 2023-04-20 | Altavant Sciences Gmbh | Treatment of subjects having pulmonary arterial hypertension with rodatristat ethyl |
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| KR20100046189A (ko) | 2007-07-11 | 2010-05-06 | 렉시컨 파마슈티컬스 인코퍼레이티드 | 폐고혈압 및 관련 질환 및 장애의 치료를 위한 방법 및 조성물 |
| TW201245183A (en) * | 2010-11-05 | 2012-11-16 | Lexicon Pharmaceuticals Inc | Solid forms of (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoic acid |
| UA119247C2 (uk) * | 2013-09-06 | 2019-05-27 | РОЙВЕНТ САЙЕНСИЗ ҐмбГ | Спіроциклічні сполуки як інгібітори триптофангідроксилази |
| US9399741B2 (en) | 2013-10-09 | 2016-07-26 | Uop Llc | Methods and apparatuses for desulfurizing hydrocarbon streams |
| KR20210102887A (ko) * | 2018-11-14 | 2021-08-20 | 알타반트 사이언시스 게엠베하 | 말초 세로토닌과 관련된 질병 또는 장애를 치료하기 위한 트립토판 하이드록실라제 1 (tph1)의 결정질 스피로사이클릭 화합물 억제제 |
| KR20210105343A (ko) | 2018-11-16 | 2021-08-26 | 알타반트 사이언시스 게엠베하 | 폐동맥 고혈압 및 관련 폐동맥 고혈압의 치료 방법 |
| US20200188399A1 (en) * | 2018-12-17 | 2020-06-18 | Altavant Sciences Gmbh | Method for treating interstitial lung disease |
| US20200188398A1 (en) * | 2018-12-17 | 2020-06-18 | Altavant Sciences Gmbh | Method for treating sarcoidosis-associated pulmonary hypertension |
| WO2020157577A1 (en) | 2019-01-30 | 2020-08-06 | Altavant Sciences Gmbh | A dosage regime and method for treating pulmonary arterial hypertension with rodatristat ethyl |
| JP2022525202A (ja) | 2019-03-15 | 2022-05-11 | アルタバント・サイエンシズ・ゲーエムベーハー | 肺動脈性肺高血圧症および各種疾患に伴う肺動脈性肺高血圧症の治療法と１日あたりの投薬量 |
| CN115379825A (zh) | 2020-01-31 | 2022-11-22 | 阿尔塔万特科学公司 | 用rodatristat治疗肺动脉高压的剂量和方法 |
| US11937070B2 (en) | 2021-07-01 | 2024-03-19 | Tencent America LLC | Layered description of space of interest |
| WO2023079486A1 (en) | 2021-11-03 | 2023-05-11 | Altavant Sciences Gmbh | Treatment of pulmonary arterial hypertension with rodatristat and ambrisentan |
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| US11911382B2 (en) | 2024-02-27 |
| CN113242736A (zh) | 2021-08-10 |
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| JP2024019691A (ja) | 2024-02-09 |
| KR20210105343A (ko) | 2021-08-26 |
| US20230000866A1 (en) | 2023-01-05 |
| JP2022507533A (ja) | 2022-01-18 |
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