CA3115296A1 - Automatic calibration and automatic maintenance of raman spectroscopic models for real-time predictions - Google Patents

Automatic calibration and automatic maintenance of raman spectroscopic models for real-time predictions Download PDF

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Publication number
CA3115296A1
CA3115296A1 CA3115296A CA3115296A CA3115296A1 CA 3115296 A1 CA3115296 A1 CA 3115296A1 CA 3115296 A CA3115296 A CA 3115296A CA 3115296 A CA3115296 A CA 3115296A CA 3115296 A1 CA3115296 A1 CA 3115296A1
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biopharmaceutical
analytical measurement
query point
biopharmaceutical process
observation
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English (en)
French (fr)
Inventor
Aditya TULSYAN
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Amgen Inc
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Amgen Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=70331744&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA3115296(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of CA3115296A1 publication Critical patent/CA3115296A1/en
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00—Machine learning
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N5/00—Computing arrangements using knowledge-based models
    • G06N5/04—Inference or reasoning models
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N2021/8411—Application to online plant, process monitoring
    • G01N2021/8416—Application to online plant, process monitoring and process controlling, not otherwise provided for
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/127—Calibration; base line adjustment; drift compensation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Software Systems (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Data Mining & Analysis (AREA)
  • Medical Informatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Artificial Intelligence (AREA)
  • Evolutionary Computation (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Computing Systems (AREA)
  • Mathematical Physics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Evolutionary Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Computational Linguistics (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
CA3115296A 2018-10-23 2019-10-23 Automatic calibration and automatic maintenance of raman spectroscopic models for real-time predictions Pending CA3115296A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862749359P 2018-10-23 2018-10-23
US62/749,359 2018-10-23
US201962833044P 2019-04-12 2019-04-12
US62/833,044 2019-04-12
US201962864565P 2019-06-21 2019-06-21
US62/864,565 2019-06-21
PCT/US2019/057513 WO2020086635A1 (en) 2018-10-23 2019-10-23 Automatic calibration and automatic maintenance of raman spectroscopic models for real-time predictions

Publications (1)

Publication Number Publication Date
CA3115296A1 true CA3115296A1 (en) 2020-04-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA3115296A Pending CA3115296A1 (en) 2018-10-23 2019-10-23 Automatic calibration and automatic maintenance of raman spectroscopic models for real-time predictions

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US (1) US20220128474A1 (enExample)
EP (1) EP3870957B1 (enExample)
JP (1) JP7601760B2 (enExample)
KR (1) KR20210078531A (enExample)
CN (1) CN112912716B (enExample)
AU (2) AU2019365102A1 (enExample)
CA (1) CA3115296A1 (enExample)
CL (1) CL2021001024A1 (enExample)
DK (1) DK3870957T3 (enExample)
ES (1) ES3041713T3 (enExample)
FI (1) FI3870957T3 (enExample)
HU (1) HUE072452T2 (enExample)
IL (1) IL281977B2 (enExample)
LT (1) LT3870957T (enExample)
MX (1) MX2021004510A (enExample)
PL (1) PL3870957T3 (enExample)
PT (1) PT3870957T (enExample)
SG (1) SG11202103232WA (enExample)
SI (1) SI3870957T1 (enExample)
TW (1) TWI844570B (enExample)
WO (1) WO2020086635A1 (enExample)

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Also Published As

Publication number Publication date
AU2019365102A1 (en) 2021-04-29
BR112021007611A2 (pt) 2021-07-27
ES3041713T3 (en) 2025-11-13
MX2021004510A (es) 2021-06-08
LT3870957T (lt) 2025-10-10
CN112912716B (zh) 2025-04-11
WO2020086635A1 (en) 2020-04-30
FI3870957T3 (fi) 2025-09-30
IL281977B1 (en) 2024-11-01
DK3870957T3 (da) 2025-09-29
JP2022512775A (ja) 2022-02-07
CN112912716A (zh) 2021-06-04
US20220128474A1 (en) 2022-04-28
TW202033949A (zh) 2020-09-16
PT3870957T (pt) 2025-09-01
CL2021001024A1 (es) 2021-09-24
KR20210078531A (ko) 2021-06-28
SG11202103232WA (en) 2021-05-28
EP3870957A1 (en) 2021-09-01
IL281977B2 (en) 2025-03-01
EP3870957B1 (en) 2025-07-16
JP7601760B2 (ja) 2024-12-17
AU2025205401A1 (en) 2025-07-31
IL281977A (en) 2021-05-31
HUE072452T2 (hu) 2025-11-28
TWI844570B (zh) 2024-06-11
PL3870957T3 (pl) 2025-11-17
SI3870957T1 (sl) 2025-10-30

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