CA3107463A1 - Antibody directed against s. aureus clumping factor a (clfa) - Google Patents
Antibody directed against s. aureus clumping factor a (clfa) Download PDFInfo
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- CA3107463A1 CA3107463A1 CA3107463A CA3107463A CA3107463A1 CA 3107463 A1 CA3107463 A1 CA 3107463A1 CA 3107463 A CA3107463 A CA 3107463A CA 3107463 A CA3107463 A CA 3107463A CA 3107463 A1 CA3107463 A1 CA 3107463A1
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Classifications
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- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K—PEPTIDES
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
- Chemical & Material Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
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| US201862702762P | 2018-07-24 | 2018-07-24 | |
| US62/702,762 | 2018-07-24 | ||
| PCT/US2019/043254 WO2020023644A2 (en) | 2018-07-24 | 2019-07-24 | Antibody directed against s. aureus clumping factor a (clfa) |
Publications (1)
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| CA3107463A1 true CA3107463A1 (en) | 2020-01-30 |
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| CA3107463A Pending CA3107463A1 (en) | 2018-07-24 | 2019-07-24 | Antibody directed against s. aureus clumping factor a (clfa) |
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| DK2917360T3 (da) * | 2012-11-06 | 2020-03-30 | Medimmune Llc | Antistoffer mod S. aureus-overflade-determinanter |
| DE102018115012A1 (de) | 2018-06-21 | 2019-12-24 | Carl Zeiss Microscopy Gmbh | Teilchenstrahlsystem |
| CA3107463A1 (en) * | 2018-07-24 | 2020-01-30 | Medimmune, Llc | Antibody directed against s. aureus clumping factor a (clfa) |
| JP7459075B2 (ja) | 2018-10-09 | 2024-04-01 | メディミューン，エルエルシー | スタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）ロイコトキシンに対して向けられた抗体 |
| CN113164602A (zh) | 2018-10-09 | 2021-07-23 | 免疫医疗有限责任公司 | 抗金黄色葡萄球菌抗体的组合 |
| TWI743626B (zh) | 2019-01-24 | 2021-10-21 | 德商卡爾蔡司多重掃描電子顯微鏡有限公司 | 包含多束粒子顯微鏡的系統、對3d樣本逐層成像之方法及電腦程式產品 |
| DE102019008249B3 (de) | 2019-11-27 | 2020-11-19 | Carl Zeiss Multisem Gmbh | Teilchenstrahl-System mit einer Multistrahl-Ablenkeinrichtung und einem Strahlfänger, Verfahren zum Betreiben des Teilchenstrahl-Systems und zugehöriges Computerprogrammprodukt |
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| CN101466406B (zh) | 2006-06-12 | 2012-06-27 | 葛兰素史密斯克蓝生物品公司 | α-毒素在治疗和预防葡萄球菌感染上的用途 |
| JP5675109B2 (ja) | 2007-02-20 | 2015-02-25 | アナプティスバイオ インコーポレイティッド | ライブラリーの生成方法及びその使用 |
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| CN101951948B (zh) | 2007-08-31 | 2015-12-09 | 芝加哥大学 | 与针对葡萄球菌性肺部疾病和病症进行免疫相关的方法和组合物 |
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| CN102695724B (zh) | 2009-05-18 | 2016-08-24 | 维尔茨堡尤利乌斯·马克西米利安大学 | 指向金黄葡萄球菌表位isaa或isab的抗体或其片段 |
| BR112012029521A2 (pt) | 2010-05-05 | 2018-03-06 | New York University | leucocidinas do staphylococcus aureus, composições terapêuticas, e aplicações das mesmas. |
| MX375113B (es) | 2011-02-08 | 2025-03-04 | Medimmune Llc | Anticuerpos que se unen específicamente a la toxina alfa de staphylococcus aureus y métodos de uso. |
| WO2012177658A2 (en) | 2011-06-19 | 2012-12-27 | New York Univeristy | Methods of treating and preventing staphylococcus aureus infections and associated conditions |
| JP6186427B2 (ja) | 2012-03-19 | 2017-08-23 | テクニファー−インダストリア テクニカ ファーマシューティカ，エス．エー． | 抗菌性ファージのカクテルを含む組成物及び細菌感染症を処置するためのその使用 |
| CN112316135A (zh) | 2012-11-06 | 2021-02-05 | 米迪缪尼有限公司 | 治疗金黄色葡萄球菌相关疾病的方法 |
| DK2917360T3 (da) | 2012-11-06 | 2020-03-30 | Medimmune Llc | Antistoffer mod S. aureus-overflade-determinanter |
| BR112016008275A2 (pt) | 2013-10-17 | 2017-10-03 | Arsanis Biosciences Gmbh | Anticorpo com reatividade cruzada ao staphylococcus aureus, preparações farmacêuticas ou para diagnóstico compreendendo o anticorpo, anticorpo para uso médico e para diagnóstico, um ácido nucleico isolado que codifica o anticorpo, plasmideo ou cassete de expressao, e célula hospedeira compreendendo tal plasmideo ou cassete de expressao, método para produzir o anticorpo usando tal célula hospedeira, método para produzir variantes de anticorpos, um cristal formado por um monômero da hla ou lukd com dito anticorpo, um paratopo isolado do anticorpo, o epítopo isolado e uma molécula de ligação ligando especificamente ao dito epítopo, um método de triagem para identificar um ligante que se liga ao dito epítopo, um imunógeno compreendendo dito epítopo, e dito imunógeno usado para induzir uma resposta imune protetora |
| US9644023B2 (en) | 2013-12-09 | 2017-05-09 | New York University | Compositions and methods for phagocyte delivery of anti-staphylococcal agents |
| BR112016014163A2 (pt) | 2013-12-19 | 2018-01-09 | Arsanis Biosciences Gmbh | anticorpos direcionados contra a toxina lukgh (lukab) de staphylococcus aureus e as sequências de anticorpos, seu uso no tratamento ou no diagnóstico de infecção por s. aureus, as preparações farmacêuticas e para diagnóstico, os ácidos nucleicos que codificam os anticorpos, o paratopo isolado dos anticorpos e o epítopo conformacional isolado |
| ES2869459T3 (es) | 2014-05-16 | 2021-10-25 | Medimmune Llc | Moléculas con unión a receptor de fc de neonato alterada que tiene propiedades terapéuticas y de diagnóstico potenciadas |
| TWI719938B (zh) | 2014-06-19 | 2021-03-01 | 美商麥迪紐有限責任公司 | 多重細菌感染之治療 |
| KR20170136637A (ko) | 2015-04-17 | 2017-12-11 | 알사니스 바이오사이언시스 게엠베하 | 항-스타필로코커스 아우레우스 항체 배합 제제 |
| US20190077851A1 (en) | 2015-10-30 | 2019-03-14 | Bruno Francois | Methods of using anti-alpha toxin antibody |
| CA3107463A1 (en) | 2018-07-24 | 2020-01-30 | Medimmune, Llc | Antibody directed against s. aureus clumping factor a (clfa) |
| JP7459075B2 (ja) | 2018-10-09 | 2024-04-01 | メディミューン，エルエルシー | スタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）ロイコトキシンに対して向けられた抗体 |
| CN113164602A (zh) | 2018-10-09 | 2021-07-23 | 免疫医疗有限责任公司 | 抗金黄色葡萄球菌抗体的组合 |
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- 2019-07-24 WO PCT/US2019/043254 patent/WO2020023644A2/en not_active Ceased
- 2019-07-24 AU AU2019309366A patent/AU2019309366B2/en active Active
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| CN112672788A (zh) | 2021-04-16 |
| CN112672788B (zh) | 2024-09-17 |
| US11970527B2 (en) | 2024-04-30 |
| TW202019956A (zh) | 2020-06-01 |
| US20220073595A1 (en) | 2022-03-10 |
| WO2020023644A3 (en) | 2020-03-19 |
| AU2019309366A1 (en) | 2021-02-18 |
| US11155606B2 (en) | 2021-10-26 |
| BR112021001214A2 (pt) | 2021-04-27 |
| CN119176871A (zh) | 2024-12-24 |
| US20200048330A1 (en) | 2020-02-13 |
| US20240352098A1 (en) | 2024-10-24 |
| WO2020023644A2 (en) | 2020-01-30 |
| JP2024105229A (ja) | 2024-08-06 |
| JP7525471B2 (ja) | 2024-07-30 |
| JP2021530244A (ja) | 2021-11-11 |
| MX2021000889A (es) | 2021-04-28 |
| EP3840838A2 (en) | 2021-06-30 |
| AU2019309366B2 (en) | 2025-06-05 |
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