CA3105328A1 - Method for producing diarylpyridine derivatives - Google Patents

Method for producing diarylpyridine derivatives Download PDF

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Publication number
CA3105328A1
CA3105328A1 CA3105328A CA3105328A CA3105328A1 CA 3105328 A1 CA3105328 A1 CA 3105328A1 CA 3105328 A CA3105328 A CA 3105328A CA 3105328 A CA3105328 A CA 3105328A CA 3105328 A1 CA3105328 A1 CA 3105328A1
Authority
CA
Canada
Prior art keywords
formula
added
contents
compound represented
stirred
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3105328A
Other languages
English (en)
French (fr)
Inventor
Yuichi Aki
Fumihiko Toriyama
Natsuki Sakurai
Ai Kameda
Tomokazu OGURA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of CA3105328A1 publication Critical patent/CA3105328A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44—Palladium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA3105328A 2018-07-04 2019-07-03 Method for producing diarylpyridine derivatives Pending CA3105328A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018-127197 2018-07-04
JP2018127197 2018-07-04
PCT/JP2019/026395 WO2020009132A1 (ja) 2018-07-04 2019-07-03 ジアリールピリジン誘導体の製造方法

Publications (1)

Publication Number Publication Date
CA3105328A1 true CA3105328A1 (en) 2020-01-09

Family

ID=69059540

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3105328A Pending CA3105328A1 (en) 2018-07-04 2019-07-03 Method for producing diarylpyridine derivatives

Country Status (10)

Country Link
US (1) US11999724B2 (cg-RX-API-DMAC7.html)
EP (1) EP3819296B1 (cg-RX-API-DMAC7.html)
JP (2) JP7337058B2 (cg-RX-API-DMAC7.html)
CN (1) CN112368271A (cg-RX-API-DMAC7.html)
AU (1) AU2019299152A1 (cg-RX-API-DMAC7.html)
CA (1) CA3105328A1 (cg-RX-API-DMAC7.html)
ES (1) ES2925365T3 (cg-RX-API-DMAC7.html)
IL (1) IL279070B2 (cg-RX-API-DMAC7.html)
TW (1) TWI840378B (cg-RX-API-DMAC7.html)
WO (1) WO2020009132A1 (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2023090337A1 (cg-RX-API-DMAC7.html) 2021-11-19 2023-05-25

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201404505PA (en) * 2012-01-31 2014-10-30 Daiichi Sankyo Co Ltd Pyridone derivative
TWI723572B (zh) * 2014-07-07 2021-04-01 日商第一三共股份有限公司 具有四氫吡喃基甲基之吡啶酮衍生物及其用途
TWI796326B (zh) 2017-03-24 2023-03-21 日商第一三共股份有限公司 含有axl抑制劑與egfr酪胺酸激酶抑制藥的醫藥品及其用途

Also Published As

Publication number Publication date
TW202005962A (zh) 2020-02-01
US20210188823A1 (en) 2021-06-24
JP2023159297A (ja) 2023-10-31
ES2925365T3 (es) 2022-10-17
IL279070B2 (en) 2024-05-01
JPWO2020009132A1 (ja) 2021-07-08
CN112368271A (zh) 2021-02-12
WO2020009132A1 (ja) 2020-01-09
EP3819296B1 (en) 2022-06-29
AU2019299152A1 (en) 2021-03-04
US11999724B2 (en) 2024-06-04
AU2019299152A2 (en) 2021-03-11
IL279070A (en) 2021-01-31
TWI840378B (zh) 2024-05-01
IL279070B1 (en) 2024-01-01
EP3819296A4 (en) 2021-06-09
EP3819296A1 (en) 2021-05-12
JP7337058B2 (ja) 2023-09-01

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20220923

B12 Application deemed to be withdrawn, abandoned or lapsed

Free format text: ST27 STATUS EVENT CODE: N-2-6-B10-B12-B303 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: DEEMED ABANDONED - FAILURE TO RESPOND TO AN EXAMINER'S REQUISITION

Effective date: 20240807