CA3095795A1 - Optimized engineered nucleases having specificity for the human t cell receptor alpha constant region gene - Google Patents

Optimized engineered nucleases having specificity for the human t cell receptor alpha constant region gene Download PDF

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Publication number
CA3095795A1
CA3095795A1 CA3095795A CA3095795A CA3095795A1 CA 3095795 A1 CA3095795 A1 CA 3095795A1 CA 3095795 A CA3095795 A CA 3095795A CA 3095795 A CA3095795 A CA 3095795A CA 3095795 A1 CA3095795 A1 CA 3095795A1
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cell
genetically
seq
sequence
cells
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French (fr)
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James Jefferson Smith
Janel LAPE
Hui Li
Jochen GENSCHEL
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Precision Biosciences Inc
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Precision Biosciences Inc
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    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N5/0634—Cells from the blood or the immune system
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
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CA3095795A 2018-04-12 2019-04-11 Optimized engineered nucleases having specificity for the human t cell receptor alpha constant region gene Pending CA3095795A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862656809P 2018-04-12 2018-04-12
US62/656,809 2018-04-12
PCT/US2019/027019 WO2019200122A1 (en) 2018-04-12 2019-04-11 Optimized engineered nucleases having specificity for the human t cell receptor alpha constant region gene

Publications (1)

Publication Number Publication Date
CA3095795A1 true CA3095795A1 (en) 2019-10-17

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CA3095795A Pending CA3095795A1 (en) 2018-04-12 2019-04-11 Optimized engineered nucleases having specificity for the human t cell receptor alpha constant region gene

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US (3) US11786554B2 (enExample)
EP (2) EP4275697A3 (enExample)
JP (3) JP7304888B2 (enExample)
KR (2) KR102617818B1 (enExample)
CN (2) CN120249250A (enExample)
AU (3) AU2019252527B2 (enExample)
CA (1) CA3095795A1 (enExample)
ES (1) ES2955408T3 (enExample)
IL (4) IL277883B2 (enExample)
MX (2) MX2020010795A (enExample)
WO (1) WO2019200122A1 (enExample)

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EP3774871C0 (en) 2023-06-28
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