CA3075482A1 - Methods and compositions for treating chronic lung diseases - Google Patents

Methods and compositions for treating chronic lung diseases Download PDF

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Publication number
CA3075482A1
CA3075482A1 CA3075482A CA3075482A CA3075482A1 CA 3075482 A1 CA3075482 A1 CA 3075482A1 CA 3075482 A CA3075482 A CA 3075482A CA 3075482 A CA3075482 A CA 3075482A CA 3075482 A1 CA3075482 A1 CA 3075482A1
Authority
CA
Canada
Prior art keywords
igf
months
weeks
analog
agonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3075482A
Other languages
English (en)
French (fr)
Inventor
Norman Barton
Alexandra MANGILI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oak Hill Bio Ltd
Original Assignee
Shire Human Genetics Therapies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Human Genetics Therapies Inc filed Critical Shire Human Genetics Therapies Inc
Publication of CA3075482A1 publication Critical patent/CA3075482A1/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1754Insulin-like growth factor binding proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CA3075482A 2017-09-11 2018-09-11 Methods and compositions for treating chronic lung diseases Pending CA3075482A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762557113P 2017-09-11 2017-09-11
US62/557,113 2017-09-11
PCT/US2018/050427 WO2019051474A1 (en) 2017-09-11 2018-09-11 METHODS AND COMPOSITIONS FOR TREATING CHRONIC PULMONARY DISEASES

Publications (1)

Publication Number Publication Date
CA3075482A1 true CA3075482A1 (en) 2019-03-14

Family

ID=63794620

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3075482A Pending CA3075482A1 (en) 2017-09-11 2018-09-11 Methods and compositions for treating chronic lung diseases

Country Status (21)

Country Link
US (3) US20190151411A1 (enExample)
EP (2) EP4663184A3 (enExample)
JP (3) JP7819893B2 (enExample)
KR (1) KR20200097679A (enExample)
CN (1) CN111432881A (enExample)
AU (2) AU2018328827B2 (enExample)
BR (1) BR112020004760A2 (enExample)
CA (1) CA3075482A1 (enExample)
CL (1) CL2020000597A1 (enExample)
CO (1) CO2020004244A2 (enExample)
EA (1) EA202090705A1 (enExample)
EC (1) ECSP20055797A (enExample)
IL (1) IL273174B2 (enExample)
MX (1) MX421623B (enExample)
MY (1) MY204825A (enExample)
PE (1) PE20201166A1 (enExample)
PH (1) PH12020500489A1 (enExample)
SG (1) SG11202002088TA (enExample)
UA (1) UA128690C2 (enExample)
WO (1) WO2019051474A1 (enExample)
ZA (1) ZA202001568B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3005966T3 (en) * 2020-10-19 2025-03-17 Oak Hill Bio Ltd Compositions suitable for use in neonates
IL316413A (en) * 2022-05-04 2024-12-01 Oak Hill Bio Ltd Combination therapy for preterm infants
WO2023242440A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
AU627423B2 (en) 1987-04-06 1992-08-27 Celtrix Pharmaceuticals, Inc. Human somatomedin carrier protein subunits and process for producing them
DK131988A (da) 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
US5258287A (en) 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
DE3854842T2 (de) 1988-04-12 1996-06-13 Amgen Boulder Inc Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktors
GB8826451D0 (en) 1988-11-11 1988-12-14 Sandoz Ltd Improvements in/relating to organic compounds
IL92816A0 (en) 1988-12-22 1990-09-17 Biogrowth Inc Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides
AU4238493A (en) 1992-05-08 1993-12-13 Thomas Jefferson University IGF-1 analogs
US5563046A (en) 1993-08-02 1996-10-08 Celtrix Pharmaceuticals, Inc. Fusion polypeptides and proteins
US5789547A (en) 1995-06-07 1998-08-04 Celtrix Pharmaceuticals, Inc. Method of producing insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
AU2002239560B2 (en) * 2000-11-28 2006-03-02 Premacure Ab Determination of risk and treatment of complications of prematurity
US8518877B2 (en) * 2007-04-18 2013-08-27 Premacure Ab Method and product for treatment and/or prevention of complications of prematurity

Also Published As

Publication number Publication date
WO2019051474A1 (en) 2019-03-14
EP4663184A3 (en) 2026-03-18
EA202090705A1 (ru) 2020-06-11
IL273174A (en) 2020-04-30
PH12020500489A1 (en) 2021-02-22
EP4663184A2 (en) 2025-12-17
US20220088132A1 (en) 2022-03-24
MY204825A (en) 2024-09-18
UA128690C2 (uk) 2024-10-02
ZA202001568B (en) 2023-09-27
US20190151411A1 (en) 2019-05-23
AU2018328827B2 (en) 2024-07-25
KR20200097679A (ko) 2020-08-19
MX2020002744A (es) 2020-10-01
EP3681602B1 (en) 2026-04-15
AU2018328827A1 (en) 2020-04-02
SG11202002088TA (en) 2020-04-29
BR112020004760A2 (pt) 2020-09-15
CN111432881A (zh) 2020-07-17
CO2020004244A2 (es) 2020-05-29
JP2025114869A (ja) 2025-08-05
AU2024227601A1 (en) 2024-11-14
IL273174B2 (en) 2024-12-01
IL273174B1 (en) 2024-08-01
AU2024227601B2 (en) 2026-04-23
MX421623B (es) 2025-03-14
JP2023145646A (ja) 2023-10-11
PE20201166A1 (es) 2020-10-28
EP3681602A1 (en) 2020-07-22
US20240415927A1 (en) 2024-12-19
JP7819893B2 (ja) 2026-02-25
CL2020000597A1 (es) 2020-12-04
JP2020533344A (ja) 2020-11-19
ECSP20055797A (es) 2020-10-30

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