CA3065481A1 - Additive manufacturing using recombinant collagen-containing formulation - Google Patents
Additive manufacturing using recombinant collagen-containing formulation Download PDFInfo
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- CA3065481A1 CA3065481A1 CA3065481A CA3065481A CA3065481A1 CA 3065481 A1 CA3065481 A1 CA 3065481A1 CA 3065481 A CA3065481 A CA 3065481A CA 3065481 A CA3065481 A CA 3065481A CA 3065481 A1 CA3065481 A1 CA 3065481A1
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3847—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3852—Cartilage, e.g. meniscus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/386—Ligaments, tendons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
- B29C64/10—Processes of additive manufacturing
- B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y70/00—Materials specially adapted for additive manufacturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y10/00—Processes of additive manufacturing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Vascular Medicine (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Manufacturing & Machinery (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Optics & Photonics (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201762517179P | 2017-06-09 | 2017-06-09 | |
| US62/517,179 | 2017-06-09 | ||
| PCT/IL2018/050627 WO2018225076A1 (en) | 2017-06-09 | 2018-06-08 | Additive manufacturing using recombinant collagen-containing formulation |
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| CA3065481A1 true CA3065481A1 (en) | 2018-12-13 |
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| CA3065481A Pending CA3065481A1 (en) | 2017-06-09 | 2018-06-08 | Additive manufacturing using recombinant collagen-containing formulation |
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| US (2) | US12115276B2 (enExample) |
| EP (1) | EP3634512A4 (enExample) |
| JP (2) | JP7339889B2 (enExample) |
| AU (1) | AU2018282131B2 (enExample) |
| CA (1) | CA3065481A1 (enExample) |
| WO (1) | WO2018225076A1 (enExample) |
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| EP3634512A4 (en) | 2017-06-09 | 2021-04-14 | CollPlant Ltd. | GENERATIVE MANUFACTURING USING A RECOMBINANT COLLAGEN-CONTAINING FORMULATION |
| IL306070A (en) | 2018-05-03 | 2023-11-01 | Collplant Ltd | Dermal fillers and their uses |
| CA3116884C (en) * | 2018-10-18 | 2023-10-17 | Regents Of The University Of Minnesota | Bioink for 3d deposition |
| EP3872182A1 (en) * | 2020-02-28 | 2021-09-01 | Alganelle | Recombinant microalgae able to produce peptides, polypeptides or proteins of collagen, elastin and their derivatives in the chloroplast of microalgae and associated method thereof |
| DK4126088T3 (da) * | 2020-03-22 | 2025-10-20 | Collplant Ltd | Collagenbaserede formuleringer, der kan anvendes som bløde vævsfyldstoffer og/eller implantater |
| CN111375088B (zh) * | 2020-04-29 | 2022-06-14 | 陕西巨子生物技术有限公司 | 双层骨软骨组织修复支架及其制备方法 |
| WO2021250186A1 (en) * | 2020-06-11 | 2021-12-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | 3d bioprinting method for forming a cell specific tissue construct |
| KR102493622B1 (ko) * | 2020-10-16 | 2023-01-31 | 주식회사 파이버엔텍 | 고강도 콜라겐 필라멘트의 제조방법 |
| US20230113487A1 (en) * | 2021-10-07 | 2023-04-13 | Technion Research & Development Foundation Limited | Curable fibrinogen and uses thereof |
| CA3235057A1 (en) * | 2021-10-27 | 2023-05-04 | Roi MASHIACH | Collagen-containing curable formulations |
| US20250026074A1 (en) * | 2021-11-04 | 2025-01-23 | The Trustees Of Princeton University | 3d-printing engineered living materials |
| WO2023096401A1 (ko) * | 2021-11-26 | 2023-06-01 | 주식회사 한국유니온 생명과학 | 아텔로콜라겐 기반 바이오 잉크 조성물 및 이를 이용하여 3차원 구조체를 제조하는 방법 |
| CN114366856B (zh) * | 2021-12-17 | 2022-11-18 | 同济大学 | 一种明胶胶原蛋白复合3d打印生物支架的方法 |
| CN114259604B (zh) * | 2021-12-17 | 2022-12-27 | 上海纳米技术及应用国家工程研究中心有限公司 | 一种3d打印促有序血管化的载药骨修复支架的制备方法及其产品和应用 |
| US20250058021A1 (en) * | 2021-12-22 | 2025-02-20 | The Regents Of The University Of Michigan | Acoustically-responsive bioinks for extrusion-based 3d-bioprinting |
| JP7609096B2 (ja) * | 2022-02-17 | 2025-01-07 | Ｊｆｅエンジニアリング株式会社 | ３次元プリンタおよび造形物の製造方法 |
| CN114470305B (zh) * | 2022-03-09 | 2023-01-03 | 南方科技大学 | 一种止血海绵及其制备方法 |
| PL4249008T3 (pl) * | 2022-03-21 | 2025-02-03 | Typeone Biomaterials S.r.l. | Kompozycja biotuszu oparta na końskim kolagenie typu I, sposób jej wytwarzania oraz jej zastosowania |
| EP4286397A1 (en) | 2022-06-01 | 2023-12-06 | ETH Zurich | Hydrogel-forming proteins |
| WO2023235832A1 (en) * | 2022-06-02 | 2023-12-07 | The Brigham And Women's Hospital, Inc. | Molecularly cleavable bioink formulation |
| EP4547691A1 (en) | 2022-07-01 | 2025-05-07 | Evonik Operations GmbH | Photocrosslinkable recombinant bacterial collagen-like proteins |
| KR20250046260A (ko) * | 2022-08-02 | 2025-04-02 | 가부시키가이샤 유니바이오 | 콜라겐 산생 방법 |
| CN115634317B (zh) * | 2022-10-20 | 2023-09-08 | 上海市第六人民医院 | 一种用于神经损伤修复的胶原纤维复合膜 |
| JP2024066199A (ja) * | 2022-11-01 | 2024-05-15 | Ｔｏｐｐａｎホールディングス株式会社 | 生体組織モデル及びその製造方法 |
| CN120882736A (zh) | 2023-03-16 | 2025-10-31 | 赢创运营有限公司 | 官能化的重组细菌胶原样蛋白 |
| KR20250158067A (ko) | 2023-03-16 | 2025-11-05 | 에보닉 오퍼레이션스 게엠베하 | 티올화된 재조합 박테리아 콜라겐-유사 단백질 |
| DE102023120769A1 (de) * | 2023-08-04 | 2025-02-06 | Cellbricks Gmbh | Verfahren zur herstellung einer tinte für den 3d-druck unter verwendung eines polypeptids auf basis von menschlichem kollagen mit reduziertem hydroxyprolin-anteil |
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| WO2006035442A2 (en) | 2004-09-29 | 2006-04-06 | Collplant Ltd. | Collagen producing plants and methods of generating and using same |
| EP2220246B1 (en) | 2007-10-26 | 2015-05-20 | Collplant Ltd. | Methods of processing recombinant procollagen |
| WO2011064773A1 (en) | 2009-11-24 | 2011-06-03 | Collplant Ltd. | Method of generating collagen fibers |
| EP2605805B1 (en) | 2010-08-20 | 2019-01-09 | Case Western Reserve University | Continuous digital light processing additive manufacturing of implants |
| WO2013093921A1 (en) | 2011-12-20 | 2013-06-27 | Collplant Ltd. | Collagen coated synthetic polymer fibers |
| US9574455B2 (en) | 2012-07-16 | 2017-02-21 | United Technologies Corporation | Blade outer air seal with cooling features |
| WO2014147622A1 (en) | 2013-03-21 | 2014-09-25 | Collplant Ltd. | Compositions comprising collagen and prp for tissue regeneration |
| EP3043835B1 (en) * | 2013-09-09 | 2020-08-12 | UAB Ferentis | Transparent hydrogel and method of making the same from functionalized natural polymers |
| EP3057624B1 (en) | 2013-10-14 | 2018-01-31 | UAB Ferentis | Regenerative prostheses as alternatives to donor corneas for transplantation |
| US10150884B2 (en) * | 2014-08-14 | 2018-12-11 | The Secant Group, Llc | Composition, methods and devices useful for manufacturing of implantable articles |
| WO2016154070A1 (en) | 2015-03-20 | 2016-09-29 | William Marsh Rice University | Hypothermic 3d bioprinting of living tissues supported by perfusable vasculature |
| US10442182B2 (en) | 2015-11-24 | 2019-10-15 | The Texas A&M University System | In vivo live 3D printing of regenerative bone healing scaffolds for rapid fracture healing |
| US20200061239A1 (en) | 2016-09-21 | 2020-02-27 | Orthopaedic Innovation Centre Inc. | Antimicrobial articles produced by additive manufacturing |
| EP3526007A4 (en) * | 2016-10-12 | 2020-05-27 | Advanced Biomatrix, Inc. | THREE-DIMENSIONAL (3-D) PRINTING INKS MANUFACTURED FROM NATURAL EXTRACELLULAR MATRIX MOLECULES |
| US10716876B2 (en) | 2017-01-12 | 2020-07-21 | Collplant Ltd. | Method of generating collagen fibers |
| US11660196B2 (en) * | 2017-04-21 | 2023-05-30 | Warsaw Orthopedic, Inc. | 3-D printing of bone grafts |
| EP3634512A4 (en) | 2017-06-09 | 2021-04-14 | CollPlant Ltd. | GENERATIVE MANUFACTURING USING A RECOMBINANT COLLAGEN-CONTAINING FORMULATION |
| US10597289B1 (en) | 2017-07-17 | 2020-03-24 | Adam Woolley | 3D printer, resin, and interconnect |
| CN118203703A (zh) | 2018-08-02 | 2024-06-18 | 朗格生物技术公共公益股份有限公司 | 用于生产接收细胞的支架的材料和方法 |
| EP4653192A2 (en) | 2019-04-26 | 2025-11-26 | William Marsh Rice University | Multivascular networks and functional intravascular topologies within biocompatible hydrogels |
| US20210229364A1 (en) | 2020-01-14 | 2021-07-29 | The Regents Of The University Of Colorado, A Body Corporate | Stereolithography with micron scale control of properties |
| US20230391000A1 (en) | 2020-10-29 | 2023-12-07 | Hewlett-Packard Development Company, L.P. | Three-dimensional printing |
| CA3235057A1 (en) | 2021-10-27 | 2023-05-04 | Roi MASHIACH | Collagen-containing curable formulations |
| CN114958079B (zh) | 2022-06-13 | 2023-02-14 | 浙江大学 | 一种高强度水凝胶作为打印墨水在光固化3d打印上的应用 |
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| WO2018225076A1 (en) | 2018-12-13 |
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| US20200179562A1 (en) | 2020-06-11 |
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