CA3065323A1 - Low-alcohol and sterilizable antimicrobial compositions and use thereof - Google Patents
Low-alcohol and sterilizable antimicrobial compositions and use thereof Download PDFInfo
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- CA3065323A1 CA3065323A1 CA3065323A CA3065323A CA3065323A1 CA 3065323 A1 CA3065323 A1 CA 3065323A1 CA 3065323 A CA3065323 A CA 3065323A CA 3065323 A CA3065323 A CA 3065323A CA 3065323 A1 CA3065323 A1 CA 3065323A1
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- composition
- alcohol
- paraben
- optionally
- acid
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- 239000000203 mixture Substances 0.000 title claims abstract description 282
- 230000000845 anti-microbial effect Effects 0.000 title claims abstract description 46
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 100
- 239000004599 antimicrobial Substances 0.000 claims abstract description 15
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 113
- FJKROLUGYXJWQN-UHFFFAOYSA-N 4-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 51
- 238000000034 method Methods 0.000 claims description 33
- 150000007524 organic acids Chemical class 0.000 claims description 28
- 230000005855 radiation Effects 0.000 claims description 28
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims description 26
- 230000001954 sterilising effect Effects 0.000 claims description 25
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 20
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 20
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 19
- 239000002562 thickening agent Substances 0.000 claims description 16
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 14
- 239000003086 colorant Substances 0.000 claims description 13
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- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 claims description 12
- 239000003974 emollient agent Substances 0.000 claims description 11
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 claims description 11
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims description 11
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 claims description 10
- 239000004744 fabric Substances 0.000 claims description 9
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- 239000004480 active ingredient Substances 0.000 claims description 6
- 150000001875 compounds Chemical class 0.000 claims description 6
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 6
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 claims description 5
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- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 3
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 2
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- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 claims 1
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- 241000222122 Candida albicans Species 0.000 claims 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 claims 1
- 229940095731 candida albicans Drugs 0.000 claims 1
- 229960003260 chlorhexidine Drugs 0.000 claims 1
- 229920006037 cross link polymer Polymers 0.000 claims 1
- 239000000645 desinfectant Substances 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
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- 230000000699 topical effect Effects 0.000 abstract description 9
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- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 24
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- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 12
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 12
- 238000009472 formulation Methods 0.000 description 12
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 10
- 150000001860 citric acid derivatives Chemical class 0.000 description 10
- 239000003349 gelling agent Substances 0.000 description 10
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 9
- 150000001298 alcohols Chemical class 0.000 description 9
- 125000000217 alkyl group Chemical group 0.000 description 9
- 230000004888 barrier function Effects 0.000 description 9
- 230000003115 biocidal effect Effects 0.000 description 9
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 8
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 8
- QMKYBPDZANOJGF-UHFFFAOYSA-N benzene-1,3,5-tricarboxylic acid Chemical compound OC(=O)C1=CC(C(O)=O)=CC(C(O)=O)=C1 QMKYBPDZANOJGF-UHFFFAOYSA-N 0.000 description 8
- 230000008859 change Effects 0.000 description 8
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 8
- 229960004063 propylene glycol Drugs 0.000 description 8
- 229940083542 sodium Drugs 0.000 description 8
- KQTIIICEAUMSDG-UHFFFAOYSA-N tricarballylic acid Chemical compound OC(=O)CC(C(O)=O)CC(O)=O KQTIIICEAUMSDG-UHFFFAOYSA-N 0.000 description 8
- ARCGXLSVLAOJQL-UHFFFAOYSA-N trimellitic acid Chemical compound OC(=O)C1=CC=C(C(O)=O)C(C(O)=O)=C1 ARCGXLSVLAOJQL-UHFFFAOYSA-N 0.000 description 8
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- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
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- CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 description 6
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- 239000004135 Bone phosphate Substances 0.000 description 4
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
- A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Oncology (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201762514635P | 2017-06-02 | 2017-06-02 | |
| US62/514,635 | 2017-06-02 | ||
| PCT/US2018/035720 WO2018223080A1 (en) | 2017-06-02 | 2018-06-01 | Low-alcohol and sterilizable antimicrobial compositions and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3065323A1 true CA3065323A1 (en) | 2018-12-06 |
Family
ID=62749185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3065323A Pending CA3065323A1 (en) | 2017-06-02 | 2018-06-01 | Low-alcohol and sterilizable antimicrobial compositions and use thereof |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210069143A1 (enExample) |
| EP (1) | EP3629734A1 (enExample) |
| JP (1) | JP7275051B2 (enExample) |
| KR (1) | KR20200032046A (enExample) |
| CN (1) | CN111050552A (enExample) |
| AU (1) | AU2018275134B2 (enExample) |
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| CA (1) | CA3065323A1 (enExample) |
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| MX (1) | MX2019014449A (enExample) |
| RU (1) | RU2019144371A (enExample) |
| WO (1) | WO2018223080A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9861102B2 (en) | 2016-05-26 | 2018-01-09 | Markesbery Blue Pearl LLC | Methods for disinfection |
| US11425911B2 (en) | 2017-05-25 | 2022-08-30 | Markesbery Blue Pearl LLC | Method for disinfection of items and spaces |
| EP4114177A4 (en) * | 2020-03-05 | 2024-12-18 | Markesbery Blue Pearl LLC | COMPOSITIONS AND SYSTEMS FOR DISINFECTION |
| EP4043004B1 (de) | 2021-01-29 | 2025-08-20 | Dr. Schumacher GmbH | Hygienegel mit hautpflegendem effekt und antimikrobieller wirksamkeit |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US1715251A (en) * | 1924-12-24 | 1929-05-28 | Sabalitschka Theodor | Disinfecting |
| GB917885A (en) * | 1961-06-20 | 1963-02-06 | Youngs Rubber Corp | Saturated pad for cleansing and deodorizing |
| BE841452A (fr) * | 1976-05-05 | 1976-09-01 | Systeme pour vaporiser la surface des paillassons avec un produit desinfectant | |
| GB8500108D0 (en) * | 1985-01-03 | 1985-02-13 | Unilever Plc | Disinfectant compositions |
| JPH02215706A (ja) * | 1989-02-16 | 1990-08-28 | Nippon Kanko Shikiso Kenkyusho:Kk | 抗微生物用組成物および化粧料 |
| IE63315B1 (en) * | 1989-04-24 | 1995-04-05 | Becton Dickinson Co | Radiation sterilizable antimicrobial ointment and process to manufacture |
| JPH05178702A (ja) * | 1991-12-27 | 1993-07-20 | Cosmo Sogo Kenkyusho:Kk | 防菌防カビ剤 |
| RU2001610C1 (ru) * | 1992-04-20 | 1993-10-30 | Kochetova Nelli P | Крем дл кожи лица |
| RU2014822C1 (ru) * | 1992-08-12 | 1994-06-30 | Парфюмерно-косметическое акционерное общество "Сувенир" | Крем для кожи лица |
| US6284739B1 (en) * | 1994-03-03 | 2001-09-04 | Max Grogl | Antileishmanial composition for topical application |
| JP2540777B2 (ja) * | 1994-03-15 | 1996-10-09 | 巌 菱田 | 液状消毒剤 |
| JPH09328404A (ja) * | 1996-06-07 | 1997-12-22 | Iwao Hishida | 殺菌、抗菌および不活化剤 |
| US6582711B1 (en) * | 1997-01-09 | 2003-06-24 | 3M Innovative Properties Company | Hydroalcoholic compositions thickened using polymers |
| JP4418976B2 (ja) * | 1998-02-24 | 2010-02-24 | 株式会社マンダム | 防腐殺菌剤及び化粧料組成物 |
| JP2002003375A (ja) | 2000-06-27 | 2002-01-09 | Shiseido Co Ltd | 抗菌性成分 |
| AU2002342726A1 (en) * | 2002-09-05 | 2004-03-29 | Menno Chemie-Vertrieb Gmbh | Means for inactivating pathogenic agents on surfaces, instruments and in contaminated fluids |
| US20070027119A1 (en) * | 2005-07-29 | 2007-02-01 | Ahmed Fahim U | Antibacterial composition and method of use |
| EP2200582B1 (fr) * | 2007-09-12 | 2013-03-20 | Galderma Research & Development | Utilisation d'excipients en tant que conservateurs et composition pharmaceutique les comprenant |
| KR100854017B1 (ko) * | 2007-12-12 | 2008-08-26 | (주)이노페이스 | 편리성이 향상된 피부 마스크 방법 |
| CN102123585A (zh) * | 2008-07-10 | 2011-07-13 | 西姆莱斯有限公司 | 包含苄醇衍生物和其他抗微生物活性化合物的组合物 |
| RU2408380C1 (ru) * | 2009-06-29 | 2011-01-10 | Пшеничников Виталий Георгиевич | Лекарственная композиция для лечения болезней суставов (варианты) |
| CN101637470B (zh) * | 2009-09-07 | 2011-06-15 | 四川省医学科学院(四川省人民医院) | 一种防治痤疮的外用药物组合物及其应用 |
| JP2011073970A (ja) | 2009-09-29 | 2011-04-14 | Sunstar Inc | 口腔用又は咽喉用組成物 |
| CN101884610B (zh) * | 2010-06-28 | 2012-07-04 | 孙淑萍 | 一种美白淡斑滋润嫩肤面膜及其制备方法 |
| JP2012024537A (ja) | 2010-07-26 | 2012-02-09 | Touki Corp | 高分子ポリマー系消臭剤組成物 |
| KR101256883B1 (ko) * | 2010-08-16 | 2013-04-22 | 청운대학교산학협력단 | 아산지역 온천수를 이용한 피부개선 화장품 조성물 |
| JP5710189B2 (ja) | 2010-09-16 | 2015-04-30 | 株式会社 資生堂 | 皮膚外用ローション剤 |
| KR101381903B1 (ko) | 2011-03-10 | 2014-04-10 | 주식회사 엘지생활건강 | 3-부톡시-1,2-프로판다이올을 함유하는 항균 또는 보존용 조성물 |
| CN102204931A (zh) * | 2011-05-26 | 2011-10-05 | 浙江工业大学 | 一种含有复方抑菌剂的氨碘肽滴眼液 |
| CN103997886B (zh) * | 2011-05-27 | 2017-07-18 | 祖雷克斯农业医药有限公司 | 处理哺乳动物乳头的方法及相关组合物 |
| CN102366361A (zh) * | 2011-10-24 | 2012-03-07 | 汕头市江源化工有限公司 | 一种美白护肤防晒水 |
| CN102885716A (zh) * | 2012-09-21 | 2013-01-23 | 苏州厦都贸易有限公司 | 一种多功能免水洗手液 |
| DK2986333T3 (da) | 2013-04-19 | 2020-09-07 | Zurex Pharma Inc | Medicinsk hudapplikatorapparat |
| KR101463943B1 (ko) * | 2013-11-18 | 2014-12-04 | 주식회사 에네스티 | 수안보 온천수와 식물 추출물 및 누에 추출물을 이용한 피부개선 화장료 조성물 |
| KR101439206B1 (ko) * | 2013-11-18 | 2014-09-12 | 주식회사 에네스티 | 수안보 온천수를 이용한 피부개선 화장료 조성물 |
| GB2535666B (en) * | 2014-04-30 | 2017-03-29 | Matoke Holdings Ltd | Antimicrobial compositions |
| CN104042495A (zh) * | 2014-05-31 | 2014-09-17 | 青岛博泓海洋生物技术有限公司 | 一种含芦荟成份润肤化妆水 |
| CN104042491A (zh) * | 2014-05-31 | 2014-09-17 | 青岛博泓海洋生物技术有限公司 | 一种润肤化妆水 |
| CN104436261A (zh) * | 2014-11-19 | 2015-03-25 | 铜陵麟安生物科技有限公司 | 一种冰箱用湿巾 |
| CN104434652A (zh) * | 2014-11-19 | 2015-03-25 | 铜陵麟安生物科技有限公司 | 一种消毒湿巾 |
| CN104997694A (zh) * | 2015-07-27 | 2015-10-28 | 吴冬梅 | 草莓生物面膜 |
| CN106474350A (zh) * | 2015-08-28 | 2017-03-08 | 吉林大学 | 一种植物抗菌素复方喷剂及其制备方法 |
| CN106035390A (zh) * | 2016-06-15 | 2016-10-26 | 寻航 | 一种放射科室用消毒剂 |
| CN106075500B (zh) * | 2016-06-23 | 2019-07-05 | 刘敏 | 一种用于b超室器械的杀菌剂及其制备方法 |
| CN106265416A (zh) * | 2016-08-09 | 2017-01-04 | 郑州景鸿畜牧科技有限公司 | 中草药护发啫喱水 |
-
2018
- 2018-06-01 US US16/618,779 patent/US20210069143A1/en not_active Abandoned
- 2018-06-01 WO PCT/US2018/035720 patent/WO2018223080A1/en not_active Ceased
- 2018-06-01 BR BR112019025452-8A patent/BR112019025452A2/pt not_active Application Discontinuation
- 2018-06-01 JP JP2019565797A patent/JP7275051B2/ja active Active
- 2018-06-01 AU AU2018275134A patent/AU2018275134B2/en not_active Expired - Fee Related
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- 2018-06-01 EP EP18734358.7A patent/EP3629734A1/en not_active Withdrawn
- 2018-06-01 CA CA3065323A patent/CA3065323A1/en active Pending
Also Published As
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| JP7275051B2 (ja) | 2023-05-17 |
| BR112019025452A2 (pt) | 2020-06-23 |
| EP3629734A1 (en) | 2020-04-08 |
| JP2020522482A (ja) | 2020-07-30 |
| CN111050552A (zh) | 2020-04-21 |
| MX2019014449A (es) | 2020-07-28 |
| IL270898B (en) | 2022-12-01 |
| IL270898B2 (en) | 2023-04-01 |
| IL270898A (en) | 2020-01-30 |
| KR20200032046A (ko) | 2020-03-25 |
| AU2018275134A1 (en) | 2020-01-16 |
| AU2018275134B2 (en) | 2024-05-23 |
| RU2019144371A (ru) | 2021-07-13 |
| WO2018223080A1 (en) | 2018-12-06 |
| US20210069143A1 (en) | 2021-03-11 |
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