CA3055289A1 - Anti-tigit antigen-binding proteins and methods of use thereof - Google Patents
Anti-tigit antigen-binding proteins and methods of use thereof Download PDFInfo
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- CA3055289A1 CA3055289A1 CA3055289A CA3055289A CA3055289A1 CA 3055289 A1 CA3055289 A1 CA 3055289A1 CA 3055289 A CA3055289 A CA 3055289A CA 3055289 A CA3055289 A CA 3055289A CA 3055289 A1 CA3055289 A1 CA 3055289A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762479042P | 2017-03-30 | 2017-03-30 | |
| US62/479,042 | 2017-03-30 | ||
| PCT/US2018/025460 WO2018183889A1 (en) | 2017-03-30 | 2018-03-30 | Anti-tigit antigen-binding proteins and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3055289A1 true CA3055289A1 (en) | 2018-10-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3055289A Pending CA3055289A1 (en) | 2017-03-30 | 2018-03-30 | Anti-tigit antigen-binding proteins and methods of use thereof |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US11453720B2 (Direct) |
| EP (1) | EP3601340A1 (Direct) |
| JP (1) | JP7335164B2 (Direct) |
| KR (1) | KR20190134605A (Direct) |
| CN (1) | CN110546163B (Direct) |
| AU (1) | AU2018243665A1 (Direct) |
| BR (1) | BR112019018378A2 (Direct) |
| CA (1) | CA3055289A1 (Direct) |
| CO (1) | CO2019009612A2 (Direct) |
| IL (1) | IL269074B2 (Direct) |
| JO (1) | JOP20190203A1 (Direct) |
| MX (1) | MX2019010440A (Direct) |
| PH (1) | PH12019502025A1 (Direct) |
| SG (1) | SG11201908092RA (Direct) |
| WO (1) | WO2018183889A1 (Direct) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11590224B2 (en) | 2015-10-01 | 2023-02-28 | Potenza Therapeutics, Inc. | Anti-TIGIT antigen-binding proteins and methods of uses thereof |
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| TW202402800A (zh) | 2017-05-01 | 2024-01-16 | 美商艾吉納斯公司 | 抗ｔｉｇｉｔ抗體類和使用彼等之方法 |
| SG11202101429YA (en) | 2018-08-23 | 2021-03-30 | Seagen Inc | Anti-tigit antibodies |
| GB201820006D0 (en) | 2018-12-07 | 2019-01-23 | Lifearc | Humanised anti-IL17BR antibody |
| MX2022015881A (es) | 2020-06-18 | 2023-01-24 | Genentech Inc | Tratamiento con anticuerpos anti-tigit y antagonistas de union al eje de pd-1. |
| WO2021262597A2 (en) | 2020-06-22 | 2021-12-30 | Ngm Biopharmaceuticals, Inc. | Lair-1-binding agents and methods of use thereof |
| TW202216778A (zh) | 2020-07-15 | 2022-05-01 | 美商安進公司 | Ｔｉｇｉｔ及ｃｄ１１２ｒ阻斷 |
| AR125753A1 (es) | 2021-05-04 | 2023-08-09 | Agenus Inc | Anticuerpos anti-tigit, anticuerpos anti-cd96 y métodos de uso de estos |
| EP4341287A4 (en) * | 2021-05-18 | 2024-12-04 | Suzhou Kanova Biopharmaceutical Co., Ltd. | ANTI-TIGIT ANTIBODIES AND THEIR USE |
| CN115466327B (zh) * | 2021-06-10 | 2025-07-08 | 北京天广实生物技术股份有限公司 | 结合tigit的抗体及其用途 |
| WO2023010094A2 (en) | 2021-07-28 | 2023-02-02 | Genentech, Inc. | Methods and compositions for treating cancer |
| WO2023056403A1 (en) | 2021-09-30 | 2023-04-06 | Genentech, Inc. | Methods for treatment of hematologic cancers using anti-tigit antibodies, anti-cd38 antibodies, and pd-1 axis binding antagonists |
| CN119856056A (zh) | 2022-06-07 | 2025-04-18 | 基因泰克公司 | 用于确定包括抗pd-l1拮抗剂和抗tight拮抗剂抗体的肺癌治疗的疗效的方法 |
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2017
- 2017-06-16 JO JOP/2019/0203A patent/JOP20190203A1/ar unknown
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2018
- 2018-03-30 SG SG11201908092R patent/SG11201908092RA/en unknown
- 2018-03-30 BR BR112019018378A patent/BR112019018378A2/pt not_active Application Discontinuation
- 2018-03-30 EP EP18718377.7A patent/EP3601340A1/en active Pending
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- 2018-03-30 JP JP2019548287A patent/JP7335164B2/ja active Active
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11590224B2 (en) | 2015-10-01 | 2023-02-28 | Potenza Therapeutics, Inc. | Anti-TIGIT antigen-binding proteins and methods of uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CO2019009612A2 (es) | 2020-01-17 |
| JP2020512973A (ja) | 2020-04-30 |
| RU2019127786A (ru) | 2021-04-30 |
| KR20190134605A (ko) | 2019-12-04 |
| IL269074B1 (en) | 2024-08-01 |
| RU2019127786A3 (Direct) | 2021-07-22 |
| US11453720B2 (en) | 2022-09-27 |
| SG11201908092RA (en) | 2019-10-30 |
| JOP20190203A1 (ar) | 2019-09-03 |
| CN110546163B (zh) | 2024-03-29 |
| JP7335164B2 (ja) | 2023-08-29 |
| IL269074B2 (en) | 2024-12-01 |
| WO2018183889A1 (en) | 2018-10-04 |
| AU2018243665A1 (en) | 2019-09-26 |
| EP3601340A1 (en) | 2020-02-05 |
| US20200095324A1 (en) | 2020-03-26 |
| IL269074A (en) | 2019-11-28 |
| PH12019502025A1 (en) | 2020-06-01 |
| MX2019010440A (es) | 2020-02-07 |
| CN110546163A (zh) | 2019-12-06 |
| BR112019018378A2 (pt) | 2020-04-07 |
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